Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells

por Arora, Sanjeevani, Heyza, Joshua, Zhang, Hao, Kalman-Maltese, Vivian, Tillison, Kristin, Floyd, Ashley M., Chalfin, Elaine M., Bepler, Gerold, Patrick, Steve M.
Publicado 2016

Targeting the DNA Repair Endonuclease ERCC1-XPF with Green Tea Polyphenol Epigallocatechin-3-Gallate (EGCG) and Its Prodrug to Enhance Cisplatin Efficacy in Human Cancer Cells

por Heyza, Joshua R., Arora, Sanjeevani, Zhang, Hao, Conner, Kayla L., Lei, Wen, Floyd, Ashley M., Deshmukh, Rahul R., Sarver, Jeffrey, Trabbic, Christopher J., Erhardt, Paul, Chan, Tak-Hang, Dou, Q. Ping, Patrick, Steve M.
Publicado 2018

APOBEC3 enzymes mediate efficacy of cisplatin and are epistatic with base excision repair and mismatch repair in platinum response

por Conner, Kayla L, Shaik, Asra N, Marshall, Katie A, Floyd, Ashley M, Ekinci, Elmira, Lindquist, Jacob, Sawant, Akshada, Lei, Wen, Adolph, Madison B, Chelico, Linda, Siriwardena, Sachini U, Bhagwat, Ashok, Kim, Seongho, Cote, Michele L, Patrick, Steve M
Publicado 2020