Intramembrane cleaving proteases (I-CLiPs) as guardians of shuttling proteins

por Fluhrer, Regina
Publicado 2014

Signaling Functions of Intramembrane Aspartyl-Proteases

por Papadopoulou, Alkmini A., Fluhrer, Regina
Publicado 2020

Physiological functions of SPP/SPPL intramembrane proteases

por Mentrup, Torben, Cabrera-Cabrera, Florencia, Fluhrer, Regina, Schröder, Bernd
Publicado 2020

Non-canonical Shedding of TNFα by SPPL2a Is Determined by the Conformational Flexibility of Its Transmembrane Helix

por Spitz, Charlotte, Schlosser, Christine, Guschtschin-Schmidt, Nadja, Stelzer, Walter, Menig, Simon, Götz, Alexander, Haug-Kröper, Martina, Scharnagl, Christina, Langosch, Dieter, Muhle-Goll, Claudia, Fluhrer, Regina
Publicado 2020

The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain

por Schneppenheim, Janna, Dressel, Ralf, Hüttl, Susann, Lüllmann-Rauch, Renate, Engelke, Michael, Dittmann, Kai, Wienands, Jürgen, Eskelinen, Eeva-Liisa, Hermans-Borgmeyer, Irm, Fluhrer, Regina, Saftig, Paul, Schröder, Bernd
Publicado 2013

Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage

por Papadopoulou, Alkmini A., Stelzer, Walter, Silber, Mara, Schlosser, Christine, Spitz, Charlotte, Haug-Kröper, Martina, Straub, Tobias, Müller, Stephan A., Lichtenthaler, Stefan F., Muhle-Goll, Claudia, Langosch, Dieter, Fluhrer, Regina
Publicado 2022

Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis

por Mentrup, Torben, Theodorou, Kosta, Cabrera-Cabrera, Florencia, Helbig, Andreas O., Happ, Kathrin, Gijbels, Marion, Gradtke, Ann-Christine, Rabe, Björn, Fukumori, Akio, Steiner, Harald, Tholey, Andreas, Fluhrer, Regina, Donners, Marjo, Schröder, Bernd
Publicado 2019

Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis

por Mentrup, Torben, Stumpff-Niggemann, Anna Yamina, Leinung, Nadja, Schlosser, Christine, Schubert, Katja, Wehner, Rebekka, Tunger, Antje, Schatz, Valentin, Neubert, Patrick, Gradtke, Ann-Christine, Wolf, Janina, Rose-John, Stefan, Saftig, Paul, Dalpke, Alexander, Jantsch, Jonathan, Schmitz, Marc, Fluhrer, Regina, Jacobsen, Ilse D., Schröder, Bernd
Publicado 2022

Antigen glycosylation regulates efficacy of CAR T cells targeting CD19

por Heard, Amanda, Landmann, Jack H., Hansen, Ava R., Papadopolou, Alkmini, Hsu, Yu-Sung, Selli, Mehmet Emrah, Warrington, John M., Lattin, John, Chang, Jufang, Ha, Helen, Haug-Kroeper, Martina, Doray, Balraj, Gill, Saar, Ruella, Marco, Hayer, Katharina E., Weitzman, Matthew D., Green, Abby M., Fluhrer, Regina, Singh, Nathan
Publicado 2022