Analyses of HIV proteases variants at the threshold of viability reveals relationships between processing efficiency and fitness

por Schneider-Nachum, Gily, Flynn, Julia, Mavor, David, Schiffer, Celia A, Bolon, Daniel N A
Publicado 2021

Comprehensive fitness maps of Hsp90 show widespread environmental dependence

por Flynn, Julia M, Rossouw, Ammeret, Cote-Hammarlof, Pamela, Fragata, Inês, Mavor, David, Hollins, Carl, Bank, Claudia, Bolon, Daniel NA
Publicado 2020

The Adaptive Potential of the Middle Domain of Yeast Hsp90

por Cote-Hammarlof, Pamela A, Fragata, Inês, Flynn, Julia, Mavor, David, Zeldovich, Konstantin B, Bank, Claudia, Bolon, Daniel N A
Publicado 2020

Comprehensive fitness landscape of SARS-CoV-2 M(pro) reveals insights into viral resistance mechanisms

por Flynn, Julia M, Samant, Neha, Schneider-Nachum, Gily, Barkan, David T, Yilmaz, Nese Kurt, Schiffer, Celia A, Moquin, Stephanie A, Dovala, Dustin, Bolon, Daniel NA
Publicado 2022

Community-based management of a five-arm randomised clinical trial in COVID-19 outpatients in South Africa: challenges and opportunities

por Chandiwana, Nomathemba, Kruger, Chelsea, Richardson, Naomi, Nxumalo, Sibongiseni, Mashilo, Nkoleleng, Dineka, Yengiwe, Mudau, Ntanganedzeni, Johnstone, Hilary, Kim, Wookyung, Ju, Chung, Arbe-Barnes, Sarah, Marrast, Anne Claire, Flynn, Julia, Venter, Willem D. Francois
Publicado 2023

Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance

por Shaqra, Ala M., Zvornicanin, Sarah N., Huang, Qiu Yu J., Lockbaum, Gordon J., Knapp, Mark, Tandeske, Laura, Bakan, David T., Flynn, Julia, Bolon, Daniel N. A., Moquin, Stephanie, Dovala, Dustin, Kurt Yilmaz, Nese, Schiffer, Celia A.
Publicado 2022

Safety, Tolerability, and Parasite Clearance Kinetics in Controlled Human Malaria Infection after Direct Venous Inoculation of Plasmodium falciparum Sporozoites: A Model for Evalua...

por Chughlay, M. Farouk, Chalon, Stephan, El Gaaloul, Myriam, Gobeau, Nathalie, Möhrle, Jörg J., Berghmans, Pieter-Jan, Van Leuven, Katrin, Marx, Michael W., Rosanas-Urgell, Anna, Flynn, Julia, Escoffier, Emilie, Izquierdo-Juncàs, Daniel, Jansen, Bastiaan, Mitov, Venelin, Kümmel, Anne, Van Geertruyden, Jean-Pierre, Barnes, Karen I.
Publicado 2022