The Current State of Naïve Human Pluripotency

por Dodsworth, Benjamin T., Flynn, Rowan, Cowley, Sally A.
Publicado 2015

Rates of homology directed repair of CRISPR-Cas9 induced double strand breaks are lower in naïve compared to primed human pluripotent stem cells

por Dodsworth, Benjamin T., Hatje, Klas, Meyer, Claas Aiko, Flynn, Rowan, Cowley, Sally A.
Publicado 2020

Correction of the ΔF508 Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Zinc-Finger Nuclease Homology-Directed Repair

por Lee, Ciaran M., Flynn, Rowan, Hollywood, Jennifer A., Scallan, Martina F., Harrison, Patrick T.
Publicado 2012

CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells

por Flynn, Rowan, Grundmann, Alexander, Renz, Peter, Hänseler, Walther, James, William S., Cowley, Sally A., Moore, Michael D.
Publicado 2015

Construction of a novel expression cassette for increasing transgene expression in vivo in endothelial cells of large blood vessels

por Dronadula, Nagadhara, Du, Liang, Flynn, Rowan, Buckler, Joshua, Kho, Jordan, Jiang, Zhilong, Tanaka, Shinji, Dichek, David A.
Publicado 2010

LRRK2 Is Recruited to Phagosomes and Co-recruits RAB8 and RAB10 in Human Pluripotent Stem Cell-Derived Macrophages

por Lee, Heyne, Flynn, Rowan, Sharma, Ishta, Haberman, Emma, Carling, Phillippa J., Nicholls, Francesca J., Stegmann, Monika, Vowles, Jane, Haenseler, Walther, Wade-Martins, Richard, James, William S., Cowley, Sally A.
Publicado 2020

Application of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons

por Überbacher, Christa, Obergasteiger, Julia, Volta, Mattia, Venezia, Serena, Müller, Stefan, Pesce, Isabella, Pizzi, Sara, Lamonaca, Giulia, Picard, Anne, Cattelan, Giada, Malpeli, Giorgio, Zoli, Michele, Beccano-Kelly, Dayne, Flynn, Rowan, Wade-Martins, Richard, Pramstaller, Peter P., Hicks, Andrew A., Cowley, Sally A., Corti, Corrado
Publicado 2019

LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

por Härtlova, Anetta, Herbst, Susanne, Peltier, Julien, Rodgers, Angela, Bilkei‐Gorzo, Orsolya, Fearns, Antony, Dill, Brian D, Lee, Heyne, Flynn, Rowan, Cowley, Sally A, Davies, Paul, Lewis, Patrick A, Ganley, Ian G, Martinez, Jennifer, Alessi, Dario R, Reith, Alastair D, Trost, Matthias, Gutierrez, Maximiliano G
Publicado 2018