Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma

por Flynt, Erin, Bisht, Kamlesh, Sridharan, Vinidhra, Ortiz, María, Towfic, Fadi, Thakurta, Anjan
Publicado 2020

Developing next generation immunomodulatory drugs and their combinations in multiple myeloma

por Thakurta, Anjan, Pierceall, William E., Amatangelo, Michael D., Flynt, Erin, Agarwal, Amit
Publicado 2021

Multiple Myeloma Patient Tumors With High Levels of Cereblon Exon-10 Deletion Splice Variant Upregulate Clinically Targetable Pro-Inflammatory Cytokine Pathways

por Karagoz, Kubra, Stokes, Matthew, Ortiz-Estévez, María, Towfic, Fadi, Flynt, Erin, Gooding, Sarah, Pierceall, William, Thakurta, Anjan
Publicado 2022

Integrative multi-omics identifies high risk multiple myeloma subgroup associated with significant DNA loss and dysregulated DNA repair and cell cycle pathways

por Ortiz-Estévez, María, Towfic, Fadi, Flynt, Erin, Stong, Nicholas, Jang, In Sock, Wang, Kai, Trotter, Matthew W. B., Thakurta, Anjan
Publicado 2021

Differential RNA splicing as a potentially important driver mechanism in multiple myeloma

por Bauer, Michael A., Ashby, Cody, Wardell, Christopher, Boyle, Eileen M., Ortiz, Maria, Flynt, Erin, Thakurta, Anjan, Morgan, Gareth, Walker, Brian A.
Publicado 2020

The location of the t(4;14) translocation breakpoint within the NSD2 gene identifies a subset of patients with high-risk NDMM

por Stong, Nicholas, Ortiz-Estévez, María, Towfic, Fadi, Samur, Mehmet, Agarwal, Amit, Corre, Jill, Flynt, Erin, Munshi, Nikhil, Avet-Loiseau, Hervé, Thakurta, Anjan
Publicado 2023

Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma

por Ansari-Pour, Naser, Samur, Mehmet, Flynt, Erin, Gooding, Sarah, Towfic, Fadi, Stong, Nicholas, Estevez, Maria Ortiz, Mavrommatis, Konstantinos, Walker, Brian, Morgan, Gareth, Munshi, Nikhil, Avet-Loiseau, Herve, Thakurta, Anjan
Publicado 2023

Loss of COP9 signalosome genes at 2q37 is associated with IMiD resistance in multiple myeloma

por Gooding, Sarah, Ansari-Pour, Naser, Kazeroun, Mohammad, Karagoz, Kubra, Polonskaia, Ann, Salazar, Mirian, Fitzsimons, Evie, Sirinukunwattana, Korsuk, Chavda, Selina, Ortiz Estevez, Maria, Towfic, Fadi, Flynt, Erin, Pierceall, William, Royston, Daniel, Yong, Kwee, Ramasamy, Karthik, Vyas, Paresh, Thakurta, Anjan
Publicado 2022

Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma

por Sudha, Parvathi, Ahsan, Aarif, Ashby, Cody, Kausar, Tasneem, Khera, Akhil, Kazeroun, Mohammad H., Hsu, Chih-Chao, Wang, Lin, Fitzsimons, Evelyn, Salminen, Outi, Blaney, Patrick, Czader, Magdalena, Williams, Jonathan, Abu Zaid, Mohammad I., Ansari-Pour, Naser, Yong, Kwee L., van Rhee, Frits, Pierceall, William E., Morgan, Gareth J., Flynt, Erin, Gooding, Sarah, Abonour, Rafat, Ramasamy, Karthik, Thakurta, Anjan, Walker, Brian A.
Publicado 2022

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

por Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith, Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Phillipe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth
Publicado 2018

Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease

por Mason, Mike J., Schinke, Carolina, Eng, Christine L. P., Towfic, Fadi, Gruber, Fred, Dervan, Andrew, White, Brian S., Pratapa, Aditya, Guan, Yuanfang, Chen, Hongjie, Cui, Yi, Li, Bailiang, Yu, Thomas, Chaibub Neto, Elias, Mavrommatis, Konstantinos, Ortiz, Maria, Lyzogubov, Valeriy, Bisht, Kamlesh, Dai, Hongyue Y., Schmitz, Frank, Flynt, Erin, Dan Rozelle, Danziger, Samuel A., Ratushny, Alexander, Dalton, William S., Goldschmidt, Hartmut, Avet-Loiseau, Herve, Samur, Mehmet, Hayete, Boris, Sonneveld, Pieter, Shain, Kenneth H., Munshi, Nikhil, Auclair, Daniel, Hose, Dirk, Morgan, Gareth, Trotter, Matthew, Bassett, Douglas, Goke, Jonathan, Walker, Brian A., Thakurta, Anjan, Guinney, Justin
Publicado 2020