Expanded Potential of the Polyamine Analogue SBP-101 (Diethyl Dihydroxyhomospermine) as a Modulator of Polyamine Metabolism and Cancer Therapeutic

por Holbert, Cassandra E., Foley, Jackson R., Murray Stewart, Tracy, Casero, Robert A.
Publicado 2022

Polyamine Homeostasis in Snyder-Robinson Syndrome

por Murray-Stewart, Tracy, Dunworth, Matthew, Foley, Jackson R., Schwartz, Charles E., Casero, Robert A.
Publicado 2018

Polyamine-Based Nanostructures Share Polyamine Transport Mechanisms with Native Polyamines and Their Analogues: Significance for Polyamine-Targeted Therapy

por Holbert, Cassandra E., Foley, Jackson R., Yu, Ao, Murray Stewart, Tracy, Phanstiel, Otto, Oupicky, David, Casero, Robert A.
Publicado 2022

Reduction of Spermine Synthase Suppresses Tau Accumulation Through Autophagy Modulation in Tauopathy

por Tao, Xianzun, Liu, Jiaqi, Diaz-Perez, Zoraida, Foley, Jackson R, Stewart, Tracy Murray, Casero, Robert A, Zhai, R. Grace
Publicado 2023

Histone deacetylase-10 liberates spermidine to support polyamine homeostasis and tumor cell growth

por Stewart, Tracy Murray, Foley, Jackson R., Holbert, Cassandra E., Klinke, Glynis, Poschet, Gernot, Steimbach, Raphael R., Miller, Aubry K., Casero, Robert A.
Publicado 2022

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome

por Stewart, Tracy Murray, Foley, Jackson R, Holbert, Cassandra E, Khomutov, Maxim, Rastkari, Noushin, Tao, Xianzun, Khomutov, Alex R, Zhai, R Grace, Casero, Robert A
Publicado 2023

Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells

por Tao, Xianzun, Zhu, Yi, Diaz-Perez, Zoraida, Yu, Seok-Ho, Foley, Jackson R., Stewart, Tracy Murray, Casero, Robert A., Steet, Richard, Zhai, R. Grace
Publicado 2022

Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis

por Padgett, Leah R., Shinkle, Mollie R., Rosario, Spencer, Stewart, Tracy Murray, Foley, Jackson R., Casero, Robert A., Park, Myung Hee, Chung, Wendy K., Mastracci, Teresa L.
Publicado 2023

Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents

por Sil, Diptesh, Panja, Sudipta, Jogdeo, Chinmay M., Kumar, Raj, Yu, Ao, Holbert, Cassandra E., Ding, Ling, Foley, Jackson R., Stewart, Tracy Murray, Casero, Robert A., Oupický, David
Publicado 2022

Impaired polyamine metabolism causes behavioral and neuroanatomical defects in a novel mouse model of Snyder-Robinson Syndrome

por Akinyele, Oluwaseun, Munir, Anushe, Johnson, Marie A., Perez, Megan S., Gao, Yuan, Foley, Jackson R., Wu, Yijen, Murray-Stewart, Tracy, Casero, Robert A., Bayir, Hulya, Kemaladewi, Dwi U.
Publicado 2023