Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication

por Khan, Shahzada, Woodruff, Erik M., Trapecar, Martin, Fontaine, Krystal A., Ezaki, Ashley, Borbet, Timothy C., Ott, Melanie, Sanjabi, Shomyseh
Publicado 2016

Neutralizing and non-neutralizing monoclonal antibodies against dengue virus E protein derived from a naturally infected patient

por Schieffelin, John S, Costin, Joshua M, Nicholson, Cindo O, Orgeron, Nicole M, Fontaine, Krystal A, Isern, Sharon, Michael, Scott F, Robinson, James E
Publicado 2010

Low expression of RNA sensors impacts Zika virus infection in the lower female reproductive tract

por Khan, Shahzada, Lew, Irene, Wu, Frank, Fritts, Linda, Fontaine, Krystal A., Tomar, Sakshi, Trapecar, Martin, Shehata, Hesham M., Ott, Melanie, Miller, Christopher J., Sanjabi, Shomyseh
Publicado 2019

The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein

por Fontaine, Krystal A., Leon, Kristoffer E., Khalid, Mir M., Tomar, Sakshi, Jimenez-Morales, David, Dunlap, Mariah, Kaye, Julia A., Shah, Priya S., Finkbeiner, Steve, Krogan, Nevan J., Ott, Melanie
Publicado 2018

Structural Optimization and De Novo Design of Dengue Virus Entry Inhibitory Peptides

por Costin, Joshua M., Jenwitheesuk, Ekachai, Lok, Shee-Mei, Hunsperger, Elizabeth, Conrads, Kelly A., Fontaine, Krystal A., Rees, Craig R., Rossmann, Michael G., Isern, Sharon, Samudrala, Ram, Michael, Scott F.
Publicado 2010

Release of Dengue Virus Genome Induced by a Peptide Inhibitor

por Lok, Shee-Mei, Costin, Joshua M., Hrobowski, Yancey M., Hoffmann, Andrew R., Rowe, Dawne K., Kukkaro, Petra, Holdaway, Heather, Chipman, Paul, Fontaine, Krystal A., Holbrook, Michael R., Garry, Robert F., Kostyuchenko, Victor, Wimley, William C., Isern, Sharon, Rossmann, Michael G., Michael, Scott F.
Publicado 2012

Nuclear accumulation of host transcripts during Zika Virus Infection

por Leon, Kristoffer E., Khalid, Mir M., Flynn, Ryan A., Fontaine, Krystal A., Nguyen, Thong T., Kumar, G. Renuka, Simoneau, Camille R., Tomar, Sakshi, Jimenez-Morales, David, Dunlap, Mariah, Kaye, Julia, Shah, Priya S., Finkbeiner, Steven, Krogan, Nevan J., Bertozzi, Carolyn, Carette, Jan E., Ott, Melanie
Publicado 2023

NF-κB inhibitor alpha has a cross-variant role during SARS-CoV-2 infection in ACE2-overexpressing human airway organoids

por Simoneau, Camille R., Chen, Pei-Yi, Xing, Galen K., Khalid, Mir M., Meyers, Nathan L., Hayashi, Jennifer M., Taha, Taha Y., Leon, Kristoffer E., Ashuach, Tal, Fontaine, Krystal A., Rodriguez, Lauren, Joehnk, Bastian, Walcott, Keith, Vasudevan, Sreelakshmi, Fang, Xiaohui, Maishan, Mazharul, Schultz, Shawn, Roose, Jeroen, Matthay, Michael A., Sil, Anita, Arjomandi, Mehrdad, Yosef, Nir, Ott, Melanie
Publicado 2022

Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins

por Hiatt, Joseph, Cavero, Devin A., McGregor, Michael J., Zheng, Weihao, Budzik, Jonathan M., Roth, Theodore L., Haas, Kelsey M., Wu, David, Rathore, Ujjwal, Meyer-Franke, Anke, Bouzidi, Mohamed S., Shifrut, Eric, Lee, Youjin, Kumar, Vigneshwari Easwar, Dang, Eric V., Gordon, David E., Wojcechowskyj, Jason A., Hultquist, Judd F., Fontaine, Krystal A., Pillai, Satish K., Cox, Jeffery S., Ernst, Joel D., Krogan, Nevan J., Marson, Alexander
Publicado 2021