Single-dose pharmacokinetics, safety, and tolerability of the dual endothelin receptor antagonist aprocitentan in subjects with moderate hepatic impairment

por Fontes, Magda S. C., Dingemanse, Jasper, Halabi, Atef, Tomaszewska-Kiecana, Monika, Sidharta, Patricia N.
Publicado 2022

A combined CaMKII inhibition and mineralocorticoid receptor antagonism via eplerenone inhibits functional deterioration in chronic pressure overloaded mice

por Driessen, Helen E., Fontes, Magda S., van Stuijvenberg, Leonie, Brans, Maike A., Goumans, Marie‐Jose, Vos, Marc A., van Veen, Toon A.
Publicado 2020

Changes in Cx43 and Na(V)1.5 Expression Precede the Occurrence of Substantial Fibrosis in Calcineurin-Induced Murine Cardiac Hypertrophy

por Fontes, Magda S. C., Raaijmakers, Antonia J. A., van Doorn, Tessa, Kok, Bart, Nieuwenhuis, Sylvia, van der Nagel, Roel, Vos, Marc A., de Boer, Teun P., van Rijen, Harold V. M., Bierhuizen, Marti F. A.
Publicado 2014

Leukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure Overload

por Wang, Jiong-Wei, Fontes, Magda S. C., Wang, Xiaoyuan, Chong, Suet Yen, Kessler, Elise L., Zhang, Ya-Nan, de Haan, Judith J., Arslan, Fatih, de Jager, Saskia C. A., Timmers, Leo, van Veen, Toon A. B., Lam, Carolyn S. P., Kleijn, Dominique P. V. de
Publicado 2017

Ventricular TLR4 Levels Abrogate TLR2-Mediated Adverse Cardiac Remodeling upon Pressure Overload in Mice

por Kessler, Elise L., Wang, Jiong-Wei, Kok, Bart, Brans, Maike A., Nederlof, Angelique, van Stuijvenberg, Leonie, Huang, Chenyuan, Vink, Aryan, Arslan, Fatih, Efimov, Igor R., Lam, Carolyn S. P., Vos, Marc A., de Kleijn, Dominique P. V., Fontes, Magda S. C., van Veen, Toon A. B.
Publicado 2021

Optical ventricular cardioversion by local optogenetic targeting and LED implantation in a cardiomyopathic rat model

por Nyns, Emile C A, Jin, Tianyi, Fontes, Magda S, van den Heuvel, Titus, Portero, Vincent, Ramsey, Catilin, Bart, Cindy I, Zeppenfeld, Katja, Schalij, Martin J, van Brakel, Thomas J, Ramkisoensing, Arti A, Zhang, Guoqi, Poelma, René H, Ördög, Balazs, de Vries, Antoine A F, Pijnappels, Daniël A
Publicado 2021