Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression

por Micalizzi, Douglas S., Farabaugh, Susan M., Ford, Heide L.
Publicado 2010

Cellular Plasticity in Breast Cancer Progression and Therapy

por Kong, Deguang, Hughes, Connor J., Ford, Heide L.
Publicado 2020

Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity

por Drasin, David J, Robin, Tyler P, Ford, Heide L
Publicado 2011

Eya2 Is Required to Mediate the Pro-Metastatic Functions of Six1 Via the Induction of TGF-β Signaling, Epithelial-Mesenchymal Transition, and Cancer Stem Cell Properties

por Farabaugh, Susan M., Micalizzi, Douglas S., Jedlicka, Paul, Zhao, Rui, Ford, Heide L.
Publicado 2011

Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3

por Wang, Chu-An, Harrell, J Chuck, Iwanaga, Ritsuko, Jedlicka, Paul, Ford, Heide L
Publicado 2014

TRAIL Receptor Signaling Regulation of Chemosensitivity In Vivo but Not In Vitro

por Menke, Christina, Goncharov, Tatiana, Qamar, Lubna, Korch, Christopher, Ford, Heide L., Behbakht, Kian, Thorburn, Andrew
Publicado 2011

Structure-Function Analyses of the Human SIX1–EYA2 Complex Reveal Insights into Metastasis and BOR Syndrome

por Patrick, Aaron N, Cabrera, Joshua H, Smith, Anna L, Chen, Xiaojiang S, Ford, Heide L, Zhao, Rui
Publicado 2013

CDK6 binds and promotes the degradation of the EYA2 protein

por Kohrt, Dawn, Crary, Jennifer, Zimmer, Marc, Patrick, Aaron N, Ford, Heide L, Hinds, Philip W, Grossel, Martha J
Publicado 2014

The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer

por Smith, Anna L., Iwanaga, Ritsuko, Drasin, David J., Micalizzi, Douglas S., Vartuli, Rebecca L, Tan, Aik-Choon, Ford, Heide L.
Publicado 2012

VEGF-C Mediates Tumor Growth and Metastasis Through Promoting EMT- Epithelial Breast Cancer cell Crosstalk

por Kong, Deguang, Zhou, Hengbo, Neelakantan, Deepika, Hughes, Connor J., Hsu, Jessica Y., Srinivasan, Ramakrishnan Rajaram, Lewis, Michael T., Ford, Heide L.
Publicado 2020

Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis

por Coletta, Ricardo D, McCoy, Erica L, Burns, Valerie, Kawakami, Kiyoshi, McManaman, James L, Wysolmerski, John J, Ford, Heide L
Publicado 2010

Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression

por Zhang, Lingdi, Zhou, Hengbo, Li, Xueni, Vartuli, Rebecca L, Rowse, Michael, Xing, Yongna, Rudra, Pratyaydipta, Ghosh, Debashis, Zhao, Rui, Ford, Heide L
Publicado 2018

Author Correction: Eya3 partners with PP2A to induce c-Myc stabilization and tumor progression

por Zhang, Lingdi, Zhou, Hengbo, Li, Xueni, Vartuli, Rebecca L., Rowse, Michael, Xing, Yongna, Rudra, Pratyaydipta, Ghosh, Debashis, Zhao, Rui, Ford, Heide L.
Publicado 2018

Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and tra...

por Iwanaga, Ritsuko, Wang, Chu-An, Micalizzi, Douglas S, Harrell, J Chuck, Jedlicka, Paul, Sartorius, Carol A, Kabos, Peter, Farabaugh, Susan M, Bradford, Andrew P, Ford, Heide L
Publicado 2012

CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming

por Kendrick, Agnieszka A., Schafer, Johnathon, Dzieciatkowska, Monika, Nemkov, Travis, D'Alessandro, Angelo, Neelakantan, Deepika, Ford, Heide L., Pearson, Chad G., Weekes, Colin D., Hansen, Kirk C., Eisenmesser, Elan Z.
Publicado 2016

EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells

por Neelakantan, Deepika, Zhou, Hengbo, Oliphant, Michael U. J., Zhang, Xiaomei, Simon, Lukas M., Henke, David M., Shaw, Chad A., Wu, Meng-Fen, Hilsenbeck, Susan G., White, Lisa D., Lewis, Michael T., Ford, Heide L.
Publicado 2017

Publisher Correction: EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells

por Neelakantan, Deepika, Zhou, Hengbo, Oliphant, Michael U. J., Zhang, Xiaomei, Simon, Lukas M., Henke, David M., Shaw, Chad A., Wu, Meng-Fen, Hilsenbeck, Susan G., White, Lisa D., Lewis, Michael T., Ford, Heide L.
Publicado 2018

SIX1 and EWS/FLI1 co-regulate an anti-metastatic gene network in Ewing Sarcoma

por Hughes, Connor J., Fields, Kaiah M., Danis, Etienne P., Hsu, Jessica Y., Neelakantan, Deepika, Vincent, Melanie Y., Gustafson, Annika L., Oliphant, Michael J., Sreekanth, Varsha, Zaberezhnyy, Vadym, Costello, James C., Jedlicka, Paul, Ford, Heide L.
Publicado 2023

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p

por Towers, Christina G., Guarnieri, Anna L., Micalizzi, Doug S., Harrell, J. Chuck, Gillen, Austin E., Kim, Jihye, Wang, Chu-An, Oliphant, Michael U.J., Drasin, David J., Guney, Michelle A., Kabos, Peter, Sartorius, Carol A., Tan, Aik-Choon, Perou, Charles M., Espinosa, Joaquin M., Ford, Heide L.
Publicado 2015

SIX1 reprograms myogenic transcription factors to maintain the rhabdomyosarcoma undifferentiated state

por Hsu, Jessica Y., Danis, Etienne P., Nance, Stephanie, O’Brien, Jenean H., Gustafson, Annika L., Wessells, Veronica M., Goodspeed, Andrew E., Talbot, Jared C., Amacher, Sharon L., Jedlicka, Paul, Black, Joshua C., Costello, James C., Durbin, Adam D., Artinger, Kristin B., Ford, Heide L.
Publicado 2022