Functional Analysis of the Cathepsin-Like Cysteine Protease Genes in Adult Brugia malayi Using RNA Interference

por Ford, Louise, Zhang, Jun, Liu, Jing, Hashmi, Sarwar, Fuhrman, Juliet A., Oksov, Yelena, Lustigman, Sara
Publicado 2009

Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes

por Johnston, Kelly L, Wu, Bo, Guimarães, Ana, Ford, Louise, Slatko, Barton E, Taylor, Mark J
Publicado 2010

Wolbachia lipoproteins: abundance, localisation and serology of Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6 from Brugia malayi...

por Voronin, Denis, Guimarães, Ana F, Molyneux, Gemma R, Johnston, Kelly L, Ford, Louise, Taylor, Mark J
Publicado 2014

Absence of Wolbachia endobacteria in the non-filariid nematodes Angiostrongylus cantonensis and A. costaricensis

por Foster, Jeremy M, Kumar, Sanjay, Ford, Louise, Johnston, Kelly L, Ben, Renata, Graeff-Teixeira, Carlos, Taylor, Mark J
Publicado 2008

Live Brugia malayi Microfilariae Inhibit Transendothelial Migration of Neutrophils and Monocytes

por Schroeder, Jan-Hendrik, Simbi, Bigboy H., Ford, Louise, Cole, Sara R., Taylor, Mark J., Lawson, Charlotte, Lawrence, Rachel A.
Publicado 2012

Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis

por Johnston, Kelly L., Ford, Louise, Umareddy, Indira, Townson, Simon, Specht, Sabine, Pfarr, Kenneth, Hoerauf, Achim, Altmeyer, Ralf, Taylor, Mark J.
Publicado 2014

Absence of Wolbachia endobacteria in the human parasitic nematode Dracunculus medinensis and two related Dracunculus species infecting wildlife

por Foster, Jeremy M, Landmann, Frédéric, Ford, Louise, Johnston, Kelly L, Elsasser, Sarah C, Schulte-Hostedde, Albrecht I, Taylor, Mark J, Slatko, Barton E
Publicado 2014

Wolbachia Lipoprotein Stimulates Innate and Adaptive Immunity through Toll-like Receptors 2 and 6 to Induce Disease Manifestations of Filariasis

por Turner, Joseph D., Langley, R. Stuart, Johnston, Kelly L., Gentil, Katrin, Ford, Louise, Wu, Bo, Graham, Maia, Sharpley, Faye, Slatko, Barton, Pearlman, Eric, Taylor, Mark J.
Publicado 2009

Combinations of registered drugs reduce treatment times required to deplete Wolbachia in the Litomosoides sigmodontis mouse model

por Specht, Sabine, Pfarr, Kenneth M., Arriens, Sandra, Hübner, Marc P., Klarmann-Schulz, Ute, Koschel, Marianne, Sternberg, Sonja, Martin, Coralie, Ford, Louise, Taylor, Mark J., Hoerauf, Achim
Publicado 2018

Macrofilaricidal Activity after Doxycycline Only Treatment of Onchocerca volvulus in an Area of Loa loa Co-Endemicity: A Randomized Controlled Trial

por Turner, Joseph D., Tendongfor, Nicholas, Esum, Mathias, Johnston, Kelly L., Langley, R. Stuart, Ford, Louise, Faragher, Brian, Specht, Sabine, Mand, Sabine, Hoerauf, Achim, Enyong, Peter, Wanji, Samuel, Taylor, Mark J.
Publicado 2010

Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library

por Johnston, Kelly L., Cook, Darren A. N., Berry, Neil G., David Hong, W., Clare, Rachel H., Goddard, Megan, Ford, Louise, Nixon, Gemma L., O’Neill, Paul M., Ward, Stephen A., Taylor, Mark J.
Publicado 2017

Wolbachia depletion blocks transmission of lymphatic filariasis by preventing chitinase-dependent parasite exsheathment

por Quek, Shannon, Cook, Darren A. N., Wu, Yang, Marriott, Amy E., Steven, Andrew, Johnston, Kelly L., Ford, Louise, Archer, John, Hemingway, Janet, Ward, Stephen A., Wagstaff, Simon C., Turner, Joseph D., Taylor, Mark J.
Publicado 2022

Comparison of Doxycycline, Minocycline, Doxycycline plus Albendazole and Albendazole Alone in Their Efficacy against Onchocerciasis in a Randomized, Open-Label, Pilot Trial

por Klarmann-Schulz, Ute, Specht, Sabine, Debrah, Alexander Yaw, Batsa, Linda, Ayisi-Boateng, Nana Kwame, Osei-Mensah, Jubin, Mubarik, Yusif, Konadu, Peter, Ricchiuto, Arcangelo, Fimmers, Rolf, Arriens, Sandra, Dubben, Bettina, Ford, Louise, Taylor, Mark, Hoerauf, Achim
Publicado 2017

Development of a High-Throughput Cytometric Screen to Identify Anti-Wolbachia Compounds: The Power of Public–Private Partnership

por Clare, Rachel H., Clark, Roger, Bardelle, Catherine, Harper, Paul, Collier, Matthew, Johnston, Kelly L., Plant, Helen, Plant, Darren, McCall, Eileen, Slatko, Barton E., Cantin, Lindsey, Wu, Bo, Ford, Louise, Murray, David, Rich, Kirsty, Wigglesworth, Mark, Taylor, Mark J., Ward, Stephen A.
Publicado 2019

Fit for purpose: do we have the right tools to sustain NTD elimination?

por Reimer, Lisa J, Adams, Emily R, Paine, Mark JI, Ranson, Hilary, Coleman, Marlize, Thomsen, Edward K, MacPherson, Eleanor E, Hollingsworth, T Deirdre, Kelly-Hope, Louise A, Bockarie, Moses J, Ford, Louise, Harrison, Robert A, Stothard, J Russell, Taylor, Mark J, Hamon, Nicholas, Torr, Stephen J
Publicado 2015

Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis

por Sharma, Raman, Jayoussi, Ghaith Al, Tyrer, Hayley E., Gamble, Joanne, Hayward, Laura, Guimaraes, Ana F., Davies, Jill, Waterhouse, David, Cook, Darren A. N., Myhill, Laura J., Clare, Rachel H., Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L., Ford, Louise, Turner, Joseph D., Ward, Stephen A., Taylor, Mark J.
Publicado 2016

Corrigendum: Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis

por Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley E., Gamble, Joanne, Hayward, Laura, Guimaraes, Ana F., Davies, Jill, Waterhouse, David, Cook, Darren A. N., Myhill, Laura J., Clare, Rachel H., Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L., Ford, Louise, Turner, Joseph D., Ward, Stephen A., Taylor, Mark J.
Publicado 2018

Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis

por McGillan, Paul, Berry, Neil G., Nixon, Gemma L., Leung, Suet C., Webborn, Peter J. H., Wenlock, Mark C., Kavanagh, Stefan, Cassidy, Andrew, Clare, Rachel H., Cook, Darren A., Johnston, Kelly L., Ford, Louise, Ward, Stephen A., Taylor, Mark J., Hong, W. David, O’Neill, Paul M.
Publicado 2021

Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis

por Turner, Joseph D., Sharma, Raman, Al Jayoussi, Ghaith, Tyrer, Hayley E., Gamble, Joanne, Hayward, Laura, Priestley, Richard S., Murphy, Emma A., Davies, Jill, Waterhouse, David, Cook, Darren A. N., Clare, Rachel H., Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L., McCall, John, Ford, Louise, Hemingway, Janet, Ward, Stephen A., Taylor, Mark J.
Publicado 2017

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis

por Aljayyoussi, Ghaith, Tyrer, Hayley E., Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas, Waterhouse, David, Davies, Jill, Gamble, Joanne, Metuge, Haelly, Cook, Darren A. N., Steven, Andrew, Sharma, Raman, Guimaraes, Ana F., Clare, Rachel H., Cassidy, Andrew, Johnston, Kelly L., Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph D., Taylor, Mark J., Ward, Stephen A.
Publicado 2017