A hybrid discrete-continuum model of immune responses to SARS-CoV-2 infection in the lung alveolar region, with a focus on interferon induced innate response

por Aristotelous, Andreas C., Chen, Alex, Forest, M. Gregory
Publicado 2022

Modeling and Simulation of Mucus Flow in Human Bronchial Epithelial Cell Cultures – Part I: Idealized Axisymmetric Swirling Flow

por Vasquez, Paula A., Jin, Yuan, Palmer, Erik, Hill, David, Forest, M. Gregory
Publicado 2016

Experimental Data and PBPK Modeling Quantify Antibody Interference in PEGylated Drug Carrier Delivery

por Talkington, Anne M., Wessler, Timothy, Lai, Samuel K., Cao, Yanguang, Forest, M. Gregory
Publicado 2021

A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors

por Newby, Jay, Schiller, Jennifer L., Wessler, Timothy, Edelstein, Jasmine, Forest, M. Gregory, Lai, Samuel K.
Publicado 2017

Transient crosslinking kinetics optimize gene cluster interactions

por Walker, Benjamin, Taylor, Dane, Lawrimore, Josh, Hult, Caitlin, Adalsteinsson, David, Bloom, Kerry, Forest, M. Gregory
Publicado 2019

Antibody-Mediated Immobilization of Virions in Mucus

por Jensen, Melanie A., Wang, Ying-Ying, Lai, Samuel K., Forest, M. Gregory, McKinley, Scott A.
Publicado 2019

Aerosol Transport Modeling: The Key Link Between Lung Infections of Individuals and Populations

por Darquenne, Chantal, Borojeni, Azadeh A.T., Colebank, Mitchel J., Forest, M. Gregory, Madas, Balázs G., Tawhai, Merryn, Jiang, Yi
Publicado 2022

Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post infection

por Pearson, Jason, Wessler, Timothy, Chen, Alex, Boucher, Richard C., Freeman, Ronit, Lai, Samuel K., Pickles, Raymond, Forest, M. Gregory
Publicado 2023

Individual pericentromeres display coordinated motion and stretching in the yeast spindle

por Stephens, Andrew D., Snider, Chloe E., Haase, Julian, Haggerty, Rachel A., Vasquez, Paula A., Forest, M. Gregory, Bloom, Kerry
Publicado 2013

Modeling Neutralization Kinetics of HIV by Broadly Neutralizing Monoclonal Antibodies in Genital Secretions Coating the Cervicovaginal Mucosa

por McKinley, Scott A., Chen, Alex, Shi, Feng, Wang, Simi, Mucha, Peter J., Forest, M. Gregory, Lai, Samuel K.
Publicado 2014

DNA loops generate intracentromere tension in mitosis

por Lawrimore, Josh, Vasquez, Paula A., Falvo, Michael R., Taylor, Russell M., Vicci, Leandra, Yeh, Elaine, Forest, M. Gregory, Bloom, Kerry
Publicado 2015

Modeling of Virion Collisions in Cervicovaginal Mucus Reveals Limits on Agglutination as the Protective Mechanism of Secretory Immunoglobulin A

por Chen, Alex, McKinley, Scott A., Shi, Feng, Wang, Simi, Mucha, Peter J., Harit, Dimple, Forest, M. Gregory, Lai, Samuel K.
Publicado 2015

Spatial heterogeneity of the cytosol revealed by machine learning-based 3D particle tracking

por McLaughlin, Grace A., Langdon, Erin M., Crutchley, John M., Holt, Liam J., Forest, M. Gregory, Newby, Jay M., Gladfelter, Amy S.
Publicado 2020

Statistical mechanics of chromosomes: in vivo and in silico approaches reveal high-level organization and structure arise exclusively through mechanical feedback between loop extru...

por He, Yunyan, Lawrimore, Josh, Cook, Diana, Van Gorder, Elizabeth Erin, De Larimat, Solenn Claire, Adalsteinsson, David, Forest, M Gregory, Bloom, Kerry
Publicado 2020

Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection

por Chen, Alexander, Wessler, Timothy, Daftari, Katherine, Hinton, Kameryn, Boucher, Richard C., Pickles, Raymond, Freeman, Ronit, Lai, Samuel K., Forest, M. Gregory
Publicado 2022

Modeling the Excess Cell Surface Stored in a Complex Morphology of Bleb-Like Protrusions

por Kapustina, Maryna, Tsygankov, Denis, Zhao, Jia, Wessler, Timothy, Yang, Xiaofeng, Chen, Alex, Roach, Nathan, Elston, Timothy C., Wang, Qi, Jacobson, Ken, Forest, M. Gregory
Publicado 2016

Baseline Goblet Cell Mucin Secretion in the Airways Exceeds Stimulated Secretion over Extended Time Periods, and Is Sensitive to Shear Stress and Intracellular Mucin Stores

por Zhu, Yunxiang, Abdullah, Lubna H., Doyle, Sean P., Nguyen, Kristine, Ribeiro, Carla M. P., Vasquez, Paula A., Forest, M. Gregory, Lethem, Michael I., Dickey, Burton F., Davis, C. William
Publicado 2015

A Biophysical Basis for Mucus Solids Concentration as a Candidate Biomarker for Airways Disease

por Hill, David B., Vasquez, Paula A., Mellnik, John, McKinley, Scott A., Vose, Aaron, Mu, Frank, Henderson, Ashley G., Donaldson, Scott H., Alexis, Neil E., Boucher, Richard C., Forest, M. Gregory
Publicado 2014

Pericentric chromatin loops function as a nonlinear spring in mitotic force balance

por Stephens, Andrew D., Haggerty, Rachel A., Vasquez, Paula A., Vicci, Leandra, Snider, Chloe E., Shi, Fu, Quammen, Cory, Mullins, Christopher, Haase, Julian, Taylor, Russell M., Verdaasdonk, Jolien S., Falvo, Michael R., Jin, Yuan, Forest, M. Gregory, Bloom, Kerry
Publicado 2013