TIL therapy and anti-CTLA4: can they co-exist?

por Forget, Marie-Andrée, Haymaker, Cara, Amaria, Rodabe N., Bernatchez, Chantale
Publicado 2019

You can run but you can't hide: tracking T cells in metastatic melanoma patients treated with tumor-infiltrating lymphocytes

por Haymaker, Cara, Forget, Marie-Andrée, Creasy, Caitlin, Ritthipichai, Krit, Hwu, Patrick, Bernatchez, Chantale
Publicado 2015

Preclinical development of tumor-infiltrating lymphocyte therapy for ovarian cancer

por Sakellariou-Thompson, Donastas, Haymaker, Cara, Forget, Marie-Andree, Jazaeri, Amir, Hwu, Patrick, Bernatchez, Chantale
Publicado 2015

Cervical Cancer Neoantigen Landscape and Immune Activity is Associated with Human Papillomavirus Master Regulators

por Qin, Yong, Ekmekcioglu, Suhendan, Forget, Marie-Andrée, Szekvolgyi, Lorant, Hwu, Patrick, Grimm, Elizabeth A., Jazaeri, Amir A., Roszik, Jason
Publicado 2017

Stimulation of Wnt/ß-Catenin Pathway in Human CD8(+) T Lymphocytes from Blood and Lung Tumors Leads to a Shared Young/Memory Phenotype

por Forget, Marie-Andrée, Huon, Yannick, Reuben, Alexandre, Grange, Cécile, Liberman, Moïshe, Martin, Jocelyne, Mes-Masson, Anne-Marie, Arbour, Nathalie, Lapointe, Réjean
Publicado 2012

Development of novel combinations of targeted and immunotherapies by understanding immune resistance using a high throughput assay of T cell mediated cytotoxicity

por Malu, Shruti, Mbofung, Rina, Khalili, Jahan, Satani, Nikunj, Forget, Marie-Andrée, Haymaker, Cara, Muller, Florian, Bernatchez, Chantale, Radvanyi, Laszlo, Hwu, Patrick
Publicado 2013

Uncovering a novel function of BTLA on tumor-infiltrating CD8+ T cells

por Haymaker, Cara, Wu, Richard, Ritthipichai, Krit, Bernatchez, Chantale, Forget, Marie-Andree, Chen, Jie Qing, Liu, Hiu, Wang, Ena, Marincola, Francesco, Hwu, Patrick, Radvanyi, Laszlo
Publicado 2013

Validation of multiplex immunofluorescence panels using multispectral microscopy for immune-profiling of formalin-fixed and paraffin-embedded human tumor tissues

por Parra, Edwin R., Uraoka, Naohiro, Jiang, Mei, Cook, Pamela, Gibbons, Don, Forget, Marie-Andrée, Bernatchez, Chantale, Haymaker, Cara, Wistuba, Ignacio I., Rodriguez-Canales, Jaime
Publicado 2017

The beneficial effects of a gas-permeable flask for expansion of Tumor-Infiltrating lymphocytes as reflected in their mitochondrial function and respiration capacity

por Forget, Marie-Andrée, Haymaker, Cara, Dennison, Jennifer B, Toth, Christopher, Maiti, Sourindra, Fulbright, Orenthial J, Cooper, Laurence J N, Hwu, Patrick, Radvanyi, Laszlo G, Bernatchez, Chantale
Publicado 2015

Genetically modified artificial antigen-presenting cells (aAPC) for expansion of melanoma tumor infiltrating lymphocytes with optimal properties for adoptive cell therapy

por Forget, Marie-Andrée, Malu, Shruti, Liu, Hiu, Toth, Christopher, Maiti, Sourindra, Kale, Charuta, Bernatchez, Chantale, Huls, Helen, Wang, Ena, Hwu, Patrick, Cooper, Laurence J, Radvanyi, Laszlo G
Publicado 2013

BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties

por Haymaker, Cara L, Wu, Richard C, Ritthipichai, Krit, Bernatchez, Chantale, Forget, Marie-Andrée, Chen, Jie Qing, Liu, Hui, Wang, Ena, Marincola, Francesco, Hwu, Patrick, Radvanyi, Laszlo G
Publicado 2015

Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

por Bailey, Peter, Chang, David K., Forget, Marie-Andrée, Lucas, Francis A. San, Alvarez, Hector A., Haymaker, Cara, Chattopadhyay, Chandrani, Kim, Sun-Hee, Ekmekcioglu, Suhendan, Grimm, Elizabeth A., Biankin, Andrew V., Hwu, Patrick, Maitra, Anirban, Roszik, Jason
Publicado 2016

CRISPR-mediated TGFBR2 knockout renders human ovarian cancer tumor-infiltrating lymphocytes resistant to TGF-β signaling

por Fix, Samantha M, Forget, Marie-Andrée, Sakellariou-Thompson, Donastas, Wang, Yunfei, Griffiths, Tamara M, Lee, Minjung, Haymaker, Cara L, Dominguez, Ana Lucía, Basar, Rafet, Reyes, Christopher, Kumar, Sanjay, Meyer, Larissa A, Hwu, Patrick, Bernatchez, Chantale, Jazaeri, Amir A
Publicado 2022

A Novel Method to Generate and Expand Clinical-Grade, Genetically Modified, Tumor-Infiltrating Lymphocytes

por Forget, Marie-Andrée, Tavera, René J., Haymaker, Cara, Ramachandran, Renjith, Malu, Shuti, Zhang, Minying, Wardell, Seth, Fulbright, Orenthial J., Toth, Chistopher Leroy, Gonzalez, Audrey M., Thorsen, Shawne T., Flores, Esteban, Wahl, Arely, Peng, Weiyi, Amaria, Rodabe N., Hwu, Patrick, Bernatchez, Chantale
Publicado 2017

Effect of neoadjuvant chemotherapy on the immune microenvironment in non–small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches

por Parra, Edwin R., Villalobos, Pamela, Behrens, Carmen, Jiang, Mei, Pataer, Apar, Swisher, Stephen G., William, William N., Zhang, Jiexin, Lee, Jack, Cascone, Tina, Heymach, John V., Forget, Marie-Andrée, Haymaker, Cara, Bernatchez, Chantale, Kalhor, Neda, Weissferdt, Annikka, Moran, Cesar, Zhang, Jianjun, Vaporciyan, Ara, Gibbons, Don L., Sepesi, Boris, Wistuba, Ignacio I.
Publicado 2018

Molecular and immune heterogeneity in synchronous melanoma metastases

por Reuben, Alexandre, Spencer, Christine, Roszik, Jason, Miller, John, Kwong, Lawrence, Jiang, Hong, Haymaker, Cara, Chen, Pei-Ling, Austin-Breneman, Jacob, Roh, Whijae, Little, Latasha, Cao, Yu, Garber, Haven, Forget, Marie-Andrée, Gopalakrishnan, Vancheswaran, Amaria, Rodabe, Davies, Michael, Bernatchez, Chantale, Roger, Edwin, Cuentas, Parra, Rodriguez, Jaime, Tetzlaff, Michael, Woodman, Scott, Dwyer, Karen, Sharma, Padmanee, Allison, James, Chin, Lynda, Futreal, Andrew, Cooper, Zachary, Wargo, Jennifer
Publicado 2015

The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy

por McKenzie, Jodi A, Mbofung, Rina M, Malu, Shruti, Zhang, Min, Ashkin, Emily, Devi, Seram, Williams, Leila, Tieu, Trang, Peng, Weiyi, Pradeep, Sunila, Xu, Chunyu, Zorro Manrique, Soraya, Liu, Chengwen, Huang, Lu, Chen, Yuan, Forget, Marie-Andree, Haymaker, Cara, Bernatchez, Chantale, Satani, Nikunj, Muller, Florian, Roszik, Jason, Kalra, Ashish, Heffernan, Timothy, Sood, Anil, Hu, Jianhua, Amaria, Rodabe, Davis, R Eric, Hwu, Patrick
Publicado 2017

Randomized phase II trial of lymphodepletion plus adoptive cell transfer of tumor-infiltrating lymphocytes, with or without dendritic cell vaccination, in patients with metastatic...

por Saberian, Chantal, Amaria, Rodabe N., Najjar, Amer M., Radvanyi, Laszlo G., Haymaker, Cara L., Forget, Marie-Andrée, Bassett, Roland L., Faria, Silvana C., Glitza, Isabella C., Alvarez, Enrique, Parshottam, Sapna, Prieto, Victor, Lizée, Gregory, Wong, Michael K., McQuade, Jennifer L., Diab, Adi, Yee, Cassian, Tawbi, Hussein A., Patel, Sapna, Shpall, Elizabeth J., Davies, Michael A., Hwu, Patrick, Bernatchez, Chantale
Publicado 2021

Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study

por Qin, Yong, Petaccia de Macedo, Mariana, Reuben, Alexandre, Forget, Marie-Andrée, Haymaker, Cara, Bernatchez, Chantale, Spencer, Christine N., Gopalakrishnan, Vancheswaran, Reddy, Sujan, Cooper, Zachary A., Fulbright, Orenthial J., Ramachandran, Renjith, Wahl, Arely, Flores, Esteban, Thorsen, Shawne T., Tavera, Rene J., Conrad, Claudius, Williams, Michelle D., Tetzlaff, Michael T., Wang, Wei-Lien, Gombos, Dan S., Esmaeli, Bita, Amaria, Rodabe N., Hwu, Patrick, Wargo, Jennifer A., Lazar, Alexander J., Patel, Sapna P.
Publicado 2017

Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy

por Sharma, Meenu, Khong, Hiep, Fa’ak, Faisal, Bentebibel, Salah-Eddine, Janssen, Louise M. E., Chesson, Brent C., Creasy, Caitlin A., Forget, Marie-Andrée, Kahn, Laura Maria S., Pazdrak, Barbara, Karki, Binisha, Hailemichael, Yared, Singh, Manisha, Vianden, Christina, Vennam, Srinivas, Bharadwaj, Uddalak, Tweardy, David J., Haymaker, Cara, Bernatchez, Chantale, Huang, Shixia, Rajapakshe, Kimal, Coarfa, Cristian, Hurwitz, Michael E., Sznol, Mario, Hwu, Patrick, Hoch, Ute, Addepalli, Murali, Charych, Deborah H., Zalevsky, Jonathan, Diab, Adi, Overwijk, Willem W.
Publicado 2020