A High-Throughput, Flow Cytometry-Based Method to Quantify DNA-End Resection in Mammalian Cells

por Forment, Josep V, Walker, Rachael V, Jackson, Stephen P
Publicado 2012

Structure-Specific DNA Endonuclease Mus81/Eme1 Generates DNA Damage Caused by Chk1 Inactivation

por Forment, Josep V., Blasius, Melanie, Guerini, Ilaria, Jackson, Stephen P.
Publicado 2011

Preventing and Overcoming Resistance to PARP Inhibitors: A Focus on the Clinical Landscape

por Prados-Carvajal, Rosario, Irving, Elsa, Lukashchuk, Natalia, Forment, Josep V.
Publicado 2021

Detection of functional protein domains by unbiased genome-wide forward genetic screening

por Herzog, Mareike, Puddu, Fabio, Coates, Julia, Geisler, Nicola, Forment, Josep V., Jackson, Stephen P.
Publicado 2018

A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1

por Blasius, Melanie, Forment, Josep V, Thakkar, Neha, Wagner, Sebastian A, Choudhary, Chunaram, Jackson, Stephen P
Publicado 2011

High-Affinity Glucose Transport in Aspergillus nidulans Is Mediated by the Products of Two Related but Differentially Expressed Genes

por Forment, Josep V., Flipphi, Michel, Ventura, Luisa, González, Ramón, Ramón, Daniel, MacCabe, Andrew P.
Publicado 2014

Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity

por Nishi, Ryotaro, Wijnhoven, Paul, le Sage, Carlos, Tjeertes, Jorrit, Galanty, Yaron, Forment, Josep V., Clague, Michael J., Urbé, Sylvie, Jackson, Stephen P
Publicado 2014

Small molecule-induced DNA damage identifies alternative DNA structures in human genes

por Rodriguez, Raphaël, Miller, Kyle M., Forment, Josep V., Bradshaw, Charles R., Nikan, Mehran, Britton, Sébastien, Oelschlaegel, Tobias, Xhemalce, Blerta, Balasubramanian, Shankar, Jackson, Stephen P.
Publicado 2012

Genome-wide genetic screening with chemically-mutagenized haploid embryonic stem cells

por Forment, Josep V., Herzog, Mareike, Coates, Julia, Konopka, Tomasz, Gapp, Bianca V., Nijman, Sebastian M., Adams, David J., Keane, Thomas M., Jackson, Stephen P.
Publicado 2016

Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition

por Jamal, Kunzah, Galbiati, Alessandro, Armenia, Joshua, Illuzzi, Giuditta, Hall, James, Bentouati, Sabrina, Barrell, Daniel, Ahdesmäki, Miika, O'Connor, Mark J., Leo, Elisabetta, Forment, Josep V.
Publicado 2022

CtIP tetramer assembly is required for DNA-end resection and repair

por Davies, Owen R., Forment, Josep V., Sun, Meidai, Belotserkovskaya, Rimma, Coates, Julia, Galanty, Yaron, Demir, Mukerrem, Morton, Christopher R., Rzechorzek, Neil J., Jackson, Stephen P., Pellegrini, Luca
Publicado 2015

Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress

por Lloyd, Rebecca L, Urban, Vaclav, Muñoz-Martínez, Francisco, Ayestaran, Iñigo, Thomas, John C, de Renty, Christelle, O’Connor, Mark J, Forment, Josep V, Galanty, Yaron, Jackson, Stephen P
Publicado 2021

C16orf72/HAPSTR1/TAPR1 functions with BRCA1/Senataxin to modulate replication-associated R-loops and confer resistance to PARP disruption

por Sharma, Abhishek Bharadwaj, Ramlee, Muhammad Khairul, Kosmin, Joel, Higgs, Martin R., Wolstenholme, Amy, Ronson, George E., Jones, Dylan, Ebner, Daniel, Shamkhi, Noor, Sims, David, Wijnhoven, Paul W. G., Forment, Josep V., Gibbs-Seymour, Ian, Lakin, Nicholas D.
Publicado 2023

Author Correction: C16orf72/HAPSTR1/TAPR1 functions with BRCA1/Senataxin to modulate replication-associated R-loops and confer resistance to PARP disruption

por Sharma, Abhishek Bharadwaj, Ramlee, Muhammad Khairul, Kosmin, Joel, Higgs, Martin R., Wolstenholme, Amy, Ronson, George E., Jones, Dylan, Ebner, Daniel, Shamkhi, Noor, Sims, David, Wijnhoven, Paul W. G., Forment, Josep V., Gibbs-Seymour, Ian, Lakin, Nicholas D.
Publicado 2023

XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data

por Kluin, Roelof J. C., Kemper, Kristel, Kuilman, Thomas, de Ruiter, Julian R., Iyer, Vivek, Forment, Josep V., Cornelissen-Steijger, Paulien, de Rink, Iris, ter Brugge, Petra, Song, Ji-Ying, Klarenbeek, Sjoerd, McDermott, Ultan, Jonkers, Jos, Velds, Arno, Adams, David J., Peeper, Daniel S., Krijgsman, Oscar
Publicado 2018

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

por Balmus, Gabriel, Pilger, Domenic, Coates, Julia, Demir, Mukerrem, Sczaniecka-Clift, Matylda, Barros, Ana C., Woods, Michael, Fu, Beiyuan, Yang, Fengtang, Chen, Elisabeth, Ostermaier, Matthias, Stankovic, Tatjana, Ponstingl, Hannes, Herzog, Mareike, Yusa, Kosuke, Martinez, Francisco Munoz, Durant, Stephen T., Galanty, Yaron, Beli, Petra, Adams, David J., Bradley, Allan, Metzakopian, Emmanouil, Forment, Josep V., Jackson, Stephen P.
Publicado 2019

Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing

por Wimberger, Sandra, Akrap, Nina, Firth, Mike, Brengdahl, Johan, Engberg, Susanna, Schwinn, Marie K., Slater, Michael R., Lundin, Anders, Hsieh, Pei-Pei, Li, Songyuan, Cerboni, Silvia, Sumner, Jonathan, Bestas, Burcu, Schiffthaler, Bastian, Magnusson, Björn, Di Castro, Silvio, Iyer, Preeti, Bohlooly-Y, Mohammad, Machleidt, Thomas, Rees, Steve, Engkvist, Ola, Norris, Tyrell, Cadogan, Elaine B., Forment, Josep V., Šviković, Saša, Akcakaya, Pinar, Taheri-Ghahfarokhi, Amir, Maresca, Marcello
Publicado 2023

Disruption of Mouse Cenpj, a Regulator of Centriole Biogenesis, Phenocopies Seckel Syndrome

por McIntyre, Rebecca E., Lakshminarasimhan Chavali, Pavithra, Ismail, Ozama, Carragher, Damian M., Sanchez-Andrade, Gabriela, Forment, Josep V., Fu, Beiyuan, Del Castillo Velasco-Herrera, Martin, Edwards, Andrew, van der Weyden, Louise, Yang, Fengtang, Ramirez-Solis, Ramiro, Estabel, Jeanne, Gallagher, Ferdia A., Logan, Darren W., Arends, Mark J., Tsang, Stephen H., Mahajan, Vinit B., Scudamore, Cheryl L., White, Jacqueline K., Jackson, Stephen P., Gergely, Fanni, Adams, David J.
Publicado 2012

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer

por Asim, Mohammad, Tarish, Firas, Zecchini, Heather I., Sanjiv, Kumar, Gelali, Eleni, Massie, Charles E., Baridi, Ajoeb, Warren, Anne Y., Zhao, Wanfeng, Ogris, Christoph, McDuffus, Leigh-Anne, Mascalchi, Patrice, Shaw, Greg, Dev, Harveer, Wadhwa, Karan, Wijnhoven, Paul, Forment, Josep V., Lyons, Scott R., Lynch, Andy G., O’Neill, Cormac, Zecchini, Vincent R., Rennie, Paul S., Baniahmad, Aria, Tavaré, Simon, Mills, Ian G., Galanty, Yaron, Crosetto, Nicola, Schultz, Niklas, Neal, David, Helleday, Thomas
Publicado 2017

Identification of a Molecularly-Defined Subset of Breast and Ovarian Cancer Models that Respond to WEE1 or ATR Inhibition, Overcoming PARP Inhibitor Resistance

por Serra, Violeta, Wang, Anderson T., Castroviejo-Bermejo, Marta, Polanska, Urszula M., Palafox, Marta, Herencia-Ropero, Andrea, Jones, Gemma N., Lai, Zhongwu, Armenia, Joshua, Michopoulos, Filippos, Llop-Guevara, Alba, Brough, Rachel, Gulati, Aditi, Pettitt, Stephen J., Bulusu, Krishna C., Nikkilä, Jenni, Wilson, Zena, Hughes, Adina, Wijnhoven, Paul W.G., Ahmed, Ambar, Bruna, Alejandra, Gris-Oliver, Albert, Guzman, Marta, Rodríguez, Olga, Grueso, Judit, Arribas, Joaquin, Cortés, Javier, Saura, Cristina, Lau, Alan, Critchlow, Susan, Dougherty, Brian, Caldas, Carlos, Mills, Gordon B., Barrett, J. Carl, Forment, Josep V., Cadogan, Elaine, Lord, Christopher J., Cruz, Cristina, Balmaña, Judith, O'Connor, Mark J.
Publicado 2022