Comparative genomic analysis of the DUF71/COG2102 family predicts roles in diphthamide biosynthesis and B12 salvage

por de Crécy-Lagard, Valérie, Forouhar, Farhad, Brochier-Armanet, Céline, Tong, Liang, Hunt, John F
Publicado 2012

Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations

por Webb, Bradley A., Forouhar, Farhad, Szu, Fu-En, Seetharaman, Jayaraman, Tong, Liang, Barber, Diane L.
Publicado 2015

Plant, Animal, and Fungal Micronutrient Queuosine Is Salvaged by Members of the DUF2419 Protein Family

por Zallot, Rémi, Brochier-Armanet, Céline, Gaston, Kirk W., Forouhar, Farhad, Limbach, Patrick A., Hunt, John F., de Crécy-Lagard, Valérie
Publicado 2014

Characterization of a patient-derived variant of GPX4 for precision therapy

por Liu, Hengrui, Forouhar, Farhad, Seibt, Tobias, Saneto, Russell, Wigby, Kristen, Friedman, Jennifer, Xia, Xin, Shchepinov, Mikhail S., Ramesh, Sanath, Conrad, Marcus, Stockwell, Brent R.
Publicado 2021

Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors

por Iketani, Sho, Forouhar, Farhad, Liu, Hengrui, Hong, Seo Jung, Lin, Fang-Yu, Nair, Manoj S., Zask, Arie, Huang, Yaoxing, Xing, Li, Stockwell, Brent R., Chavez, Alejandro, Ho, David D.
Publicado 2020

Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors

por Iketani, Sho, Forouhar, Farhad, Liu, Hengrui, Hong, Seo Jung, Lin, Fang-Yu, Nair, Manoj S., Zask, Arie, Huang, Yaoxing, Xing, Li, Stockwell, Brent R., Chavez, Alejandro, Ho, David D.
Publicado 2021

Author Correction: Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors

por Iketani, Sho, Forouhar, Farhad, Liu, Hengrui, Hong, Seo Jung, Lin, Fang-Yu, Nair, Manoj S., Zask, Arie, Huang, Yaoxing, Xing, Li, Stockwell, Brent R., Chavez, Alejandro, Ho, David D.
Publicado 2021

Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase

por Lewis-Ballester, Ariel, Forouhar, Farhad, Kim, Sung-Mi, Lew, Scott, Wang, YongQiang, Karkashon, Shay, Seetharaman, Jayaraman, Batabyal, Dipanwita, Chiang, Bing-Yu, Hussain, Munif, Correia, Maria Almira, Yeh, Syun-Ru, Tong, Liang
Publicado 2016

A case study of an integrative genomic and experimental therapeutic approach for rare tumors: identification of vulnerabilities in a pediatric poorly differentiated carcinoma

por Dela Cruz, Filemon S., Diolaiti, Daniel, Turk, Andrew T., Rainey, Allison R., Ambesi-Impiombato, Alberto, Andrews, Stuart J., Mansukhani, Mahesh M., Nagy, Peter L., Alvarez, Mariano J., Califano, Andrea, Forouhar, Farhad, Modzelewski, Beata, Mitchell, Chelsey M., Yamashiro, Darrell J., Marks, Lianna J., Bender, Julia L. Glade, Kung, Andrew L.
Publicado 2016

The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

por Morgado-Palacin, Lucia, Brown, Jessie A., Martinez, Thomas F., Garcia-Pedrero, Juana M., Forouhar, Farhad, Quinn, S. Aidan, Reglero, Clara, Vaughan, Joan, Heydary, Yasamin Hajy, Donaldson, Cynthia, Rodriguez-Perales, Sandra, Allonca, Eva, Granda-Diaz, Rocio, Fernandez, Agustin F., Fraga, Mario F., Kim, Arianna L., Santos-Juanes, Jorge, Owens, David M., Rodrigo, Juan P., Saghatelian, Alan, Ferrando, Adolfo A.
Publicado 2023

Crystal Structures of Malonyl-Coenzyme A Decarboxylase Provide Insights into Its Catalytic Mechanism and Disease-Causing Mutations

por Froese, D. Sean, Forouhar, Farhad, Tran, Timothy H., Vollmar, Melanie, Kim, Yi Seul, Lew, Scott, Neely, Helen, Seetharaman, Jayaraman, Shen, Yang, Xiao, Rong, Acton, Thomas B., Everett, John K., Cannone, Giuseppe, Puranik, Sriharsha, Savitsky, Pavel, Krojer, Tobias, Pilka, Ewa S., Kiyani, Wasim, Lee, Wen Hwa, Marsden, Brian D., von Delft, Frank, Allerston, Charles K., Spagnolo, Laura, Gileadi, Opher, Montelione, Gaetano T., Oppermann, Udo, Yue, Wyatt W., Tong, Liang
Publicado 2013

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

por Liu, Hengrui, Iketani, Sho, Zask, Arie, Khanizeman, Nisha, Bednarova, Eva, Forouhar, Farhad, Fowler, Brandon, Hong, Seo Jung, Mohri, Hiroshi, Nair, Manoj S., Huang, Yaoxing, Tay, Nicholas E. S., Lee, Sumin, Karan, Charles, Resnick, Samuel J., Quinn, Colette, Li, Wenjing, Shion, Henry, Xia, Xin, Daniels, Jacob D., Bartolo-Cruz, Michelle, Farina, Marcelo, Rajbhandari, Presha, Jurtschenko, Christopher, Lauber, Matthew A., McDonald, Thomas, Stokes, Michael E., Hurst, Brett L., Rovis, Tomislav, Chavez, Alejandro, Ho, David D., Stockwell, Brent R.
Publicado 2022