MiDAS—Meaningful Immunogenetic Data at Scale

por Migdal, Maciej, Ruan, Dan Fu, Forrest, William F., Horowitz, Amir, Hammer, Christian
Publicado 2021

Identifying and mitigating batch effects in whole genome sequencing data

por Tom, Jennifer A., Reeder, Jens, Forrest, William F., Graham, Robert R., Hunkapiller, Julie, Behrens, Timothy W., Bhangale, Tushar R.
Publicado 2017

Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens

por Fortin, Jean-Philippe, Tan, Jenille, Gascoigne, Karen E., Haverty, Peter M., Forrest, William F., Costa, Michael R., Martin, Scott E.
Publicado 2019

Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration

por Lim, Yoong Wearn, Chen-Harris, Haiyin, Mayba, Oleg, Lianoglou, Steve, Wuster, Arthur, Bhangale, Tushar, Khan, Zia, Mariathasan, Sanjeev, Daemen, Anneleen, Reeder, Jens, Haverty, Peter M., Forrest, William F., Brauer, Matthew, Mellman, Ira, Albert, Matthew L.
Publicado 2018

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes

por Hewings, David S., Heideker, Johanna, Ma, Taylur P., AhYoung, Andrew P., El Oualid, Farid, Amore, Alessia, Costakes, Gregory T., Kirchhofer, Daniel, Brasher, Bradley, Pillow, Thomas, Popovych, Nataliya, Maurer, Till, Schwerdtfeger, Carsten, Forrest, William F., Yu, Kebing, Flygare, John, Bogyo, Matthew, Wertz, Ingrid E.
Publicado 2018

BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats

por Weber, Martin, Wu, Tiffany, Meilandt, William J., Dominguez, Sara L., Solanoy, Hilda O., Maloney, Janice A., Ngu, Hai, Baca, Miriam, Kung, Chung, Lima, Lisa, Earr, Timothy K., Fleck, Daniel, Shields, Shannon D., Forrest, William F., Foreman, Oded, Warming, Søren, Watts, Ryan J., Scearce-Levie, Kimberly
Publicado 2017

Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms

por Haug-Baltzell, Asher, Bhangale, Tushar R., Chang, Diana, Dressen, Amy, Yaspan, Brian L., Ortmann, Ward, Brauer, Matthew J., Hunkapiller, Julie, Reeder, Jens, Mukhyala, Kiran, Cuenco, Karen T., Tom, Jennifer A., Cowgill, Amy, Vogel, Jan, Forrest, William F., Behrens, Timothy W., Graham, Robert R., Wuster, Arthur
Publicado 2018

The molecular landscape of high-risk early breast cancer: comprehensive biomarker analysis of a phase III adjuvant population

por Wilson, Timothy R, Yu, Jianjun, Lu, Xuyang, Spoerke, Jill M, Xiao, Yuanyuan, O’Brien, Carol, Savage, Heidi M, Huw, Ling-Yuh, Zou, Wei, Koeppen, Hartmut, Forrest, William F, Fridlyand, Jane, Fu, Ling, Tam, Rachel, Schleifman, Erica B, Sumiyoshi, Teiko, Molinero, Luciana, Hampton, Garret M, O’Shaughnessy, Joyce A, Lackner, Mark R
Publicado 2016

Ocular phenotypes in a mouse model of impaired glucocerebrosidase activity

por Weber, Martin, Min, Sang-Won, Truong, Tom, Hung, Jeffrey, Dale, Stephanie, Reichelt, Mike, Ubhayakar, Savita, Cain-Hom, Carol, Baca, Miriam, Jiang, Zhiyu, Li, Qingling, Brendza, Robert, Lin, Han, Kung, Chung, Forrest, William F., Quiason-Huynh, Cristine, Sandoval, Wendy, Chen, Buyun, Deng, Yuzhong, Easton, Amy, Foreman, Oded, Sene, Abdoulaye, Bingol, Baris
Publicado 2021

A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk

por Chang, Diana, Hunkapiller, Julie, Bhangale, Tushar, Reeder, Jens, Mukhyala, Kiran, Tom, Jennifer, Cowgill, Amy, Vogel, Jan, Forrest, William F., Khan, Zia, Stockwell, Amy, McCarthy, Mark I., Staton, Tracy L., Olsson, Julie, Holweg, Cecile T. J., Cheung, Dorothy S., Chen, Hubert, Brauer, Matthew J., Graham, Robert R., Behrens, Timothy, Wilson, Mark S., Arron, Joseph R., Choy, David F., Yaspan, Brian L.
Publicado 2022

RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy

por Song, Kyung W., Edgar, Kyle A., Hanan, Emily J., Hafner, Marc, Oeh, Jason, Merchant, Mark, Sampath, Deepak, Nannini, Michelle A., Hong, Rebecca, Phu, Lilian, Forrest, William F., Stawiski, Eric, Schmidt, Stephen, Endres, Nicholas, Guan, Jane, Wallin, Jeffrey J., Cheong, Jonathan, Plise, Emile G., Lewis Phillips, Gail D., Salphati, Laurent, Heffron, Timothy P., Olivero, Alan G., Malek, Shiva, Staben, Steven T., Kirkpatrick, Donald S., Dey, Anwesha, Friedman, Lori S.
Publicado 2022

Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents

por Ong, Christy C, Gierke, Sarah, Pitt, Cameron, Sagolla, Meredith, Cheng, Christine K, Zhou, Wei, Jubb, Adrian M, Strickland, Laura, Schmidt, Maike, Duron, Sergio G, Campbell, David A, Zheng, Wei, Dehdashti, Seameen, Shen, Min, Yang, Nora, Behnke, Mark L, Huang, Wenwei, McKew, John C, Chernoff, Jonathan, Forrest, William F, Haverty, Peter M, Chin, Suet-Feung, Rakha, Emad A, Green, Andrew R, Ellis, Ian O, Caldas, Carlos, O’Brien, Thomas, Friedman, Lori S, Koeppen, Hartmut, Rudolph, Joachim, Hoeflich, Klaus P
Publicado 2015