Three different brain tumours evolving from a common origin

por Forshew, T, Lewis, P, Waldman, A, Peterson, D, Glaser, M, Brock, C, Sheer, D, Mulholland, P J
Publicado 2013

CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma

por Apps, J. R., Stache, C., Gonzalez‐Meljem, J. M., Gutteridge, A., Chalker, J., Jacques, T. S., Forshew, T., Hölsken, A., Martinez‐Barbera, J. P.
Publicado 2020

Early plasma circulating tumor DNA (ctDNA) changes predict response to first-line pembrolizumab-based therapy in non-small cell lung cancer (NSCLC)

por Ricciuti, Biagio, Jones, Greg, Severgnini, Mariano, Alessi, Joao V, Recondo, Gonzalo, Lawrence, Marissa, Forshew, Tim, Lydon, Christine, Nishino, Mizuki, Cheng, Michael, Awad, Mark
Publicado 2021

Mutant p53 cancers reprogram macrophages to tumor supporting macrophages via exosomal miR-1246

por Cooks, Tomer, Pateras, Ioannis S., Jenkins, Lisa M., Patel, Keval M., Robles, Ana I., Morris, James, Forshew, Tim, Appella, Ettore, Gorgoulis, Vassilis G., Harris, Curtis C.
Publicado 2018

Liquid BIOpsy for MiNimal RESidual DiSease Detection in Head and Neck Squamous Cell Carcinoma (LIONESS)—a personalised circulating tumour DNA analysis in head and neck squamous cel...

por Flach, Susanne, Howarth, Karen, Hackinger, Sophie, Pipinikas, Christodoulos, Ellis, Pete, McLay, Kirsten, Marsico, Giovanni, Forshew, Tim, Walz, Christoph, Reichel, Christoph A., Gires, Olivier, Canis, Martin, Baumeister, Philipp
Publicado 2022

Molecular analysis of pediatric brain tumors identifies microRNAs in pilocytic astrocytomas that target the MAPK and NF-κB pathways

por Jones, Tania A., Jeyapalan, Jennie N., Forshew, Tim, Tatevossian, Ruth G., Lawson, Andrew R. J., Patel, Sheena N., Doctor, Gabriel T., Mumin, Muhammad A., Picker, Simon R., Phipps, Kim P., Michalski, Antony, Jacques, Thomas S., Sheer, Denise
Publicado 2015

Digital PCR analysis of circulating tumor DNA: a biomarker for chondrosarcoma diagnosis, prognostication, and residual disease detection

por Gutteridge, Alice, Rathbone, Victoria M., Gibbons, Rebecca, Bi, Mark, Archard, Nicholas, Davies, Kate E. J., Brown, Jake, Plagnol, Vincent, Pillay, Nischalan, Amary, Fernanda, O'Donnell, Paul, Gupta, Manu, Tirabosco, Roberto, Flanagan, Adrienne M., Forshew, Tim
Publicado 2017

Comprehensive molecular characterisation of epilepsy-associated glioneuronal tumours

por Stone, Thomas J., Keeley, Angus, Virasami, Alex, Harkness, William, Tisdall, Martin, Izquierdo Delgado, Elisa, Gutteridge, Alice, Brooks, Tony, Kristiansen, Mark, Chalker, Jane, Wilkhu, Lisa, Mifsud, William, Apps, John, Thom, Maria, Hubank, Mike, Forshew, Tim, Cross, J. Helen, Hargrave, Darren, Ham, Jonathan, Jacques, Thomas S.
Publicado 2017

Association Of Plasma And Urinary Mutant DNA With Clinical Outcomes In Muscle Invasive Bladder Cancer

por Patel, K. M., van der Vos, K. E., Smith, C. G., Mouliere, F., Tsui, D., Morris, J., Chandrananda, D., Marass, F., van den Broek, D., Neal, D. E., Gnanapragasam, V. J., Forshew, T., van Rhijn, B. W., Massie, C. E., Rosenfeld, N., van der Heijden, M. S.
Publicado 2017

Dynamics of multiple resistance mechanisms in plasma DNA during EGFR‐targeted therapies in non‐small cell lung cancer

por Tsui, Dana Wai Yi, Murtaza, Muhammed, Wong, Alvin Seng Cheong, Rueda, Oscar M, Smith, Christopher G, Chandrananda, Dineika, Soo, Ross A, Lim, Hong Liang, Goh, Boon Cher, Caldas, Carlos, Forshew, Tim, Gale, Davina, Liu, Wei, Morris, James, Marass, Francesco, Eisen, Tim, Chin, Tan Min, Rosenfeld, Nitzan
Publicado 2018

Glioblastoma adaptation traced through decline of an IDH1 clonal driver and macro-evolution of a double-minute chromosome

por Favero, F., McGranahan, N., Salm, M., Birkbak, N. J., Sanborn, J. Z., Benz, S. C., Becq, J., Peden, J. F., Kingsbury, Z., Grocok, R. J., Humphray, S., Bentley, D., Spencer-Dene, B., Gutteridge, A., Brada, M., Roger, S., Dietrich, P.-Y., Forshew, T., Gerlinger, M., Rowan, A., Stamp, G., Eklund, A. C., Szallasi, Z., Swanton, C.
Publicado 2015

Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling

por Plagnol, Vincent, Woodhouse, Samuel, Howarth, Karen, Lensing, Stefanie, Smith, Matt, Epstein, Michael, Madi, Mikidache, Smalley, Sarah, Leroy, Catherine, Hinton, Jonathan, de Kievit, Frank, Musgrave-Brown, Esther, Herd, Colin, Baker-Neblett, Katherine, Brennan, Will, Dimitrov, Peter, Campbell, Nathan, Morris, Clive, Rosenfeld, Nitzan, Clark, James, Gale, Davina, Platt, Jamie, Calaway, John, Jones, Greg, Forshew, Tim
Publicado 2018

Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA

por Gale, Davina, Lawson, Andrew R. J., Howarth, Karen, Madi, Mikidache, Durham, Bradley, Smalley, Sarah, Calaway, John, Blais, Shannon, Jones, Greg, Clark, James, Dimitrov, Peter, Pugh, Michelle, Woodhouse, Samuel, Epstein, Michael, Fernandez-Gonzalez, Ana, Whale, Alexandra S., Huggett, Jim F., Foy, Carole A., Jones, Gerwyn M., Raveh-Amit, Hadas, Schmitt, Karin, Devonshire, Alison, Green, Emma, Forshew, Tim, Plagnol, Vincent, Rosenfeld, Nitzan
Publicado 2018

Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis

por Weaver, Jamie M.J., Ross-Innes, Caryn S., Shannon, Nicholas, Lynch, Andy G., Forshew, Tim, Barbera, Mariagnese, Murtaza, Muhammed, Ong, Chin-Ann J., Lao-Sirieix, Pierre, Dunning, Mark J, Smith, Laura, Smith, Mike L., Anderson, Charlotte L., Carvalho, Benilton, O’Donovan, Maria, Underwood, Timothy J., May, Andrew P, Grehan, Nicola, Hardwick, Richard, Davies, Jim, Oloumi, Arusha, Aparicio, Sam, Caldas, Carlos, Eldridge, Matthew D., Edwards, Paul A.W., Rosenfeld, Nitzan, Tavaré, Simon, Fitzgerald, Rebecca C
Publicado 2014

Functional diversity and co-operativity between subclonal populations of paediatric glioblastoma and diffuse intrinsic pontine glioma cells

por Vinci, Mara, Burford, Anna, Molinari, Valeria, Kessler, Ketty, Popov, Sergey, Clarke, Matthew, Taylor, Kathryn R, Pemberton, Helen, Lord, Christopher J, Gutteridge, Alice, Forshew, Tim, Carvalho, Diana, Marshall, Lynley V, Qin, Elizabeth Y, Ingram, Wendy J, Moore, Andrew S, Ng, Ho-Keung, Trabelsi, Saoussen, Brahim, Dorra H’mida-Ben, Entz-Werle, Natacha, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C, Bridges, Leslie R, Martin, Andrew J, Al-Sarraj, Safa, Chandler, Christopher, Sunol, Mariona, Mora, Jaume, de Torres, Carmen, Cruz, Ofelia, Carcaboso, Angel M, Monje, Michelle, Mackay, Alan, Jones, Chris
Publicado 2018