Glycolysis Induces MCJ Expression That Links T Cell Proliferation With Caspase-3 Activity and Death

por Secinaro, Michael A., Fortner, Karen A., Collins, Cheryl, Rincón, Mercedes, Budd, Ralph C.
Publicado 2019

Apoptosis Regulators Fas and Bim Cooperate in Shutdown of Chronic Immune Responses and Prevention of Autoimmunity

por Hughes, Peter D., Belz, Gabrielle T., Fortner, Karen A., Budd, Ralph C., Strasser, Andreas, Bouillet, Philippe
Publicado 2008

Selective DNA Demethylation Accompanies T Cell Homeostatic Proliferation and Gene Regulation in Lupus-Prone lpr Mice

por Scharer, Christopher D., Fortner, Karen A., Dragon, Julie A., Tighe, Scott, Boss, Jeremy M., Budd, Ralph C.
Publicado 2020

Glycolysis promotes caspase-3 activation in lipid rafts in T cells

por Secinaro, Michael A., Fortner, Karen A., Dienz, Oliver, Logan, Angela, Murphy, Michael P., Anathy, Vikas, Boyson, Jonathan E., Budd, Ralph C.
Publicado 2018

Activation of the p38 Mitogen-Activated Protein Kinase Pathway Arrests Cell Cycle Progression and Differentiation of Immature Thymocytes in Vivo

por Diehl, Nicole L., Enslen, Hervé, Fortner, Karen A., Merritt, Chris, Stetson, Nate, Charland, Colette, Flavell, Richard A., Davis, Roger J., Rincón, Mercedes
Publicado 2000

IL-6 promotes the differentiation of a subset of naive CD8(+) T cells into IL-21–producing B helper CD8(+) T cells

por Yang, Rui, Masters, April R., Fortner, Karen A., Champagne, Devin P., Yanguas-Casás, Natalia, Silberger, Daniel J., Weaver, Casey T., Haynes, Laura, Rincon, Mercedes
Publicado 2016

Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice

por Fortner, Karen A, Blanco, Luz P, Buskiewicz, Iwona, Huang, Nick, Gibson, Pamela C, Cook, Deborah L, Pedersen, Hege L, Yuen, Peter S T, Murphy, Michael P, Perl, Andras, Kaplan, Mariana J, Budd, Ralph C
Publicado 2020

Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

por Giddings, Emily L., Champagne, Devin P., Wu, Meng-Han, Laffin, Joshua M., Thornton, Tina M., Valenca-Pereira, Felipe, Culp-Hill, Rachel, Fortner, Karen A., Romero, Natalia, East, James, Cao, Phoebe, Arias-Pulido, Hugo, Sidhu, Karatatiwant S., Silverstrim, Brian, Kam, Yoonseok, Kelley, Shana, Pereira, Mark, Bates, Susan E., Bunn, Janice Y., Fiering, Steven N., Matthews, Dwight E., Robey, Robert W., Stich, Domink, D’Alessandro, Angelo, Rincon, Mercedes
Publicado 2021

Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation

por Barbier-Torres, Lucía, Fortner, Karen A., Iruzubieta, Paula, Delgado, Teresa C., Giddings, Emily, Chen, Youdinghuan, Champagne, Devin, Fernández-Ramos, David, Mestre, Daniela, Gomez-Santos, Beatriz, Varela-Rey, Marta, de Juan, Virginia Gutiérrez, Fernández-Tussy, Pablo, Zubiete-Franco, Imanol, García-Monzón, Carmelo, González-Rodríguez, Águeda, Oza, Dhaval, Valença-Pereira, Felipe, Fang, Qian, Crespo, Javier, Aspichueta, Patricia, Tremblay, Frederic, Christensen, Brock C., Anguita, Juan, Martínez-Chantar, María Luz, Rincón, Mercedes
Publicado 2020