Vitamin B6 Metabolism Determines T Cell Anti-Tumor Responses

por Bargiela, David, Cunha, Pedro P., Veliça, Pedro, Foskolou, Iosifina P., Barbieri, Laura, Rundqvist, Helene, Johnson, Randall S.
Publicado 2022

Lactate exposure shapes the metabolic and transcriptomic profile of CD8+ T cells

por Barbieri, Laura, Veliça, Pedro, Gameiro, Paulo A., Cunha, Pedro P., Foskolou, Iosifina P., Rullman, Eric, Bargiela, David, Johnson, Randall S., Rundqvist, Helene
Publicado 2023

Replication Stress and Chromatin Context Link ATM Activation to a Role in DNA Replication

por Olcina, Monica M., Foskolou, Iosifina P., Anbalagan, Selvakumar, Senra, Joana M., Pires, Isabel M., Jiang, Yanyan, Ryan, Anderson J., Hammond, Ester M.
Publicado 2013

Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication

por Foskolou, Iosifina P., Jorgensen, Christian, Leszczynska, Katarzyna B., Olcina, Monica M., Tarhonskaya, Hanna, Haisma, Bauke, D’Angiolella, Vincenzo, Myers, William K., Domene, Carmen, Flashman, Emily, Hammond, Ester M.
Publicado 2017

Oxygen levels at the time of activation determine T cell persistence and immunotherapeutic efficacy

por Cunha, Pedro P, Minogue, Eleanor, Krause, Lena CM, Hess, Rita M, Bargiela, David, Wadsworth, Brennan J, Barbieri, Laura, Brombach, Carolin, Foskolou, Iosifina P, Bogeski, Ivan, Velica, Pedro, Johnson, Randall S
Publicado 2023

Infiltration of Tumors Is Regulated by T cell–Intrinsic Nitric Oxide Synthesis

por Cunha, Pedro P., Bargiela, David, Minogue, Eleanor, Krause, Lena C.M., Barbieri, Laura, Brombach, Carolin, Gojkovic, Milos, Marklund, Emilia, Pietsch, Sandra, Foskolou, Iosifina, Branco, Cristina M., Veliça, Pedro, Johnson, Randall S.
Publicado 2023

Hypoxia-induced SETX links replication stress with the unfolded protein response

por Ramachandran, Shaliny, Ma, Tiffany S., Griffin, Jon, Ng, Natalie, Foskolou, Iosifina P., Hwang, Ming-Shih, Victori, Pedro, Cheng, Wei-Chen, Buffa, Francesca M., Leszczynska, Katarzyna B., El-Khamisy, Sherif F., Gromak, Natalia, Hammond, Ester M.
Publicado 2021

Glutarate regulates T cell metabolism and anti-tumour immunity

por Minogue, Eleanor, Cunha, Pedro P., Wadsworth, Brennan J., Grice, Guinevere L., Sah-Teli, Shiv K., Hughes, Rob, Bargiela, David, Quaranta, Alessandro, Zurita, Javier, Antrobus, Robin, Velica, Pedro, Barbieri, Laura, Wheelock, Craig E., Koivunen, Peppi, Nathan, James A., Foskolou, Iosifina P., Johnson, Randall S.
Publicado 2023