A model-informed method to retrieve intrinsic from apparent cooperativity and project cellular target occupancy for ternary complex-forming compounds

por Stein, Richard R., Fouché, Marianne, Kearns, Jeffrey D., Roth, Hans-Joerg
Publicado 2023

Polar/apolar interfaces modulate the conformational behavior of cyclic peptides with impact on their passive membrane permeability

por Linker, Stephanie M., Schellhaas, Christian, Ries, Benjamin, Roth, Hans-Jörg, Fouché, Marianne, Rodde, Stephane, Riniker, Sereina
Publicado 2022

Lessons for Oral Bioavailability: How Conformationally Flexible Cyclic Peptides Enter and Cross Lipid Membranes

por Linker, Stephanie M., Schellhaas, Christian, Kamenik, Anna S., Veldhuizen, Mac M., Waibl, Franz, Roth, Hans-Jörg, Fouché, Marianne, Rodde, Stephane, Riniker, Sereina
Publicado 2023