OR23-5 A Model “Obesogen”, Tributyltin, Promotes Steatosis in Human Liver Cells by Upregulating Lipogenic Gene Expression as a Consequence of Alterations in Both Genomic and Non-Ge...

por Chen, Yue, Trevino, Lindsey, Katz, Tiffany, Hamilton, Ross, Malovannaya, Anna, Stossi, Fabio, Coarfa, Cristian, Foulds, Charles
Publicado 2019

Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells

por Stossi, Fabio, Dandekar, Radhika D., Johnson, Hannah, Lavere, Philip, Foulds, Charles E., Mancini, Maureen G., Mancini, Michael A.
Publicado 2019

CARM1 methylates MED12 to regulate its RNA-binding ability

por Cheng, Donghang, Vemulapalli, Vidyasiri, Lu, Yue, Shen, Jianjun, Aoyagi, Sayura, Fry, Christopher J, Yang, Yanzhong, Foulds, Charles E, Stossi, Fabio, Treviño, Lindsey S, Mancini, Michael A, O'Malley, Bert W, Walker, Cheryl L, Boyer, Thomas G, Bedford, Mark T
Publicado 2018

Kinome Reprogramming Is a Targetable Vulnerability in ESR1 Fusion-Driven Breast Cancer

por Gou, Xuxu, Kim, Beom-Jun, Anurag, Meenakshi, Lei, Jonathan T., Young, Meggie N., Holt, Matthew V., Fandino, Diana, Vollert, Craig T., Singh, Purba, Alzubi, Mohammad A., Malovannaya, Anna, Dobrolecki, Lacey E., Lewis, Michael T., Li, Shunqiang, Foulds, Charles E., Ellis, Matthew J.
Publicado 2023

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer

por Dasgupta, Subhamoy, Rajapakshe, Kimal, Zhu, Bokai, Nikolai, Bryan C., Yi, Ping, Putluri, Nagireddy, Choi, Jong Min, Jung, Sung Y., Coarfa, Cristian, Westbrook, Thomas F., Zhang, Xiang H.-F., Foulds, Charles E., Tsai, Sophia Y., Tsai, Ming-Jer, O’Malley, Bert W.
Publicado 2018

Hepatic Tumor Formation in Adult Mice Developmentally Exposed to Organotin

por Katz, Tiffany A., Grimm, Sandra L., Kaushal, Akhilesh, Dong, Jianrong, Treviño, Lindsey S., Jangid, Rahul K., Gaitán, Adriana V., Bertocchio, Jean-Philippe, Guan, Youchen, Robertson, Matthew J., Cabrera, Robert M., Finegold, Milton J., Foulds, Charles E., Coarfa, Cristian, Walker, Cheryl Lyn
Publicado 2020

The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells

por Maximov, Philipp Y., Abderrahman, Balkees, Hawsawi, Yousef M., Chen, Yue, Foulds, Charles E., Jain, Antrix, Malovannaya, Anna, Fan, Ping, Curpan, Ramona F., Han, Ross, Fanning, Sean W., Broom, Bradley M., Quintana Rincon, Daniela M., Greenland, Jeffery A., Greene, Geoffrey L., Jordan, V. Craig
Publicado 2020

Transcriptional Reprogramming Differentiates Active from Inactive ESR1 Fusions in Endocrine Therapy-Refractory Metastatic Breast Cancer

por Gou, Xuxu, Anurag, Meenakshi, Lei, Jonathan T., Kim, Beom-Jun, Singh, Purba, Seker, Sinem, Fandino, Diana, Han, Airi, Rehman, Saif, Hu, Jianhong, Korchina, Viktoriya, Doddapaneni, Harshavardhan, Dobrolecki, Lacey E., Mitsiades, Nicholas, Lewis, Michael T., Welm, Alana L., Li, Shunqiang, Lee, Adrian V., Robinson, Dan R., Foulds, Charles E., Ellis, Matthew J.
Publicado 2021

Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood

por Treviño, Lindsey S., Dong, Jianrong, Kaushal, Ahkilesh, Katz, Tiffany A., Jangid, Rahul Kumar, Robertson, Matthew J., Grimm, Sandra L., Ambati, Chandra Shekar R., Putluri, Vasanta, Cox, Aaron R., Kim, Kang Ho, May, Thaddeus D., Gallo, Morgan R., Moore, David D., Hartig, Sean M., Foulds, Charles E., Putluri, Nagireddy, Coarfa, Cristian, Walker, Cheryl Lyn
Publicado 2020

The Signaling Pathways Project, an integrated ‘omics knowledgebase for mammalian cellular signaling pathways

por Ochsner, Scott A., Abraham, David, Martin, Kirt, Ding, Wei, McOwiti, Apollo, Kankanamge, Wasula, Wang, Zichen, Andreano, Kaitlyn, Hamilton, Ross A., Chen, Yue, Hamilton, Angelica, Gantner, Marin L., Dehart, Michael, Qu, Shijing, Hilsenbeck, Susan G., Becnel, Lauren B., Bridges, Dave, Ma’ayan, Avi, Huss, Janice M., Stossi, Fabio, Foulds, Charles E., Kralli, Anastasia, McDonnell, Donald P., McKenna, Neil J.
Publicado 2019

Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets

por Gates, Leah A., Gu, Guowei, Chen, Yue, Rohira, Aarti D., Lei, Jonathan T., Hamilton, Ross A., Yu, Yang, Lonard, David M., Wang, Jin, Wang, Shu-Ping, Edwards, David G., Lavere, Philip F., Shao, Jiangyong, Yi, Ping, Jain, Antrix, Jung, Sung Yun, Malovannaya, Anna, Li, Shunqiang, Shao, Jieya, Roeder, Robert G., Ellis, Matthew J., Qin, Jun, Fuqua, Suzanne A. W., O’Malley, Bert W., Foulds, Charles E.
Publicado 2018

Hormonal Modulation of ESR1 Mutant Metastasis

por Gu, Guowei, Tian, Lin, Herzog, Sarah K., Rechoum, Yassine, Gelsomino, Luca, Gao, Meng, Du, Lili, Kim, Jin-Ah, Dustin, Derek, Lo, Hin Ching, Beyer, Amanda R., Edwards, David G., Gonzalez, Thomas, Tsimelzon, Anna, Huang, Helen J., Fernandez, Natalie M., Grimm, Sandra L., Hilsenbeck, Susan G., Liu, Dan, Xu, Jun, Alaniz, Alyssa, Li, Shunqiang, Mills, Gordon B., Janku, Filip, Kittler, Ralf, Zhang, Xiang H.-F., Coarfa, Cristian, Foulds, Charles E., Symmans, W. Fraser., Andò, Sebastiano, Fuqua, Suzanne A.W.
Publicado 2020