The mitochondrial permeability transition pore activates the mitochondrial unfolded protein response and promotes aging

por Angeli, Suzanne, Foulger, Anna, Chamoli, Manish, Peiris, Tanuja Harshani, Gerencser, Akos, Shahmirzadi, Azar Asadi, Andersen, Julie, Lithgow, Gordon
Publicado 2021

Amyloid β accelerates age-related proteome-wide protein insolubility.

por Anderton, Edward, Chamoli, Manish, Bhaumik, Dipa, King, Christina D., Xie, Xueshu, Foulger, Anna, Andersen, Julie K., Schilling, Birgit, Lithgow, Gordon J.
Publicado 2023

An aco-2::gfp knock-in enables the monitoring of mitochondrial morphology throughout C. elegans lifespan.

por Begelman, David V., Woods, Georgia, Bhaumik, Dipa, Angeli, Suzanne, Foulger, Anna C, Lucanic, Mark, Lan, Jianfeng, Andersen, Julie K., Lithgow, Gordon J.
Publicado 2022

Caenorhabditis Intervention Testing Program: the herbicide diuron does not robustly extend lifespan in nematodes

por Osman, Hadley C, Sedore, Christine A, Jackson, E Grace, Battistoni, Elena T, Hall, David, Foulger, Anna, Lucanic, Mark, Guo, Max, Driscoll, Monica, Phillips, Patrick, Lithgow, Gordon J
Publicado 2021

Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes

por Onken, Brian, Sedore, Christine A., Coleman‐Hulbert, Anna L., Hall, David, Johnson, Erik, Jones, Eleanor Grace, Banse, Stephen A., Huynh, Phu, Guo, Suzhen, Xue, Jian, Chen, Esteban, Harinath, Girish, Foulger, Anna C., Chao, Elizabeth A., Hope, June, Bhaumik, Dipa, Plummer, Todd, Inman, Delaney, Morshead, Mackenzie, Guo, Max, Lithgow, Gordon J., Phillips, Patrick C., Driscoll, Monica
Publicado 2021

Automated lifespan determination across Caenorhabditis strains and species reveals assay-specific effects of chemical interventions

por Banse, Stephen A., Lucanic, Mark, Sedore, Christine A., Coleman-Hulbert, Anna L., Plummer, W. Todd, Chen, Esteban, Kish, Jason L., Hall, David, Onken, Brian, Presley, Michael P., Jones, E. Grace, Blue, Benjamin W., Garrett, Theo, Abbott, Mark, Xue, Jian, Guo, Suzhen, Johnson, Erik, Foulger, Anna C., Chamoli, Manish, Falkowski, Ron, Melentijevic, Ilija, Harinath, Girish, Huynh, Phu, Patel, Shobhna, Edgar, Daniel, Jarrett, Cody M., Guo, Max, Kapahi, Pankaj, Lithgow, Gordon J., Driscoll, Monica, Phillips, Patrick C.
Publicado 2019

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

por Lucanic, Mark, Plummer, W. Todd, Chen, Esteban, Harke, Jailynn, Foulger, Anna C., Onken, Brian, Coleman-Hulbert, Anna L., Dumas, Kathleen J., Guo, Suzhen, Johnson, Erik, Bhaumik, Dipa, Xue, Jian, Crist, Anna B., Presley, Michael P., Harinath, Girish, Sedore, Christine A., Chamoli, Manish, Kamat, Shaunak, Chen, Michelle K., Angeli, Suzanne, Chang, Christina, Willis, John H., Edgar, Daniel, Royal, Mary Anne, Chao, Elizabeth A., Patel, Shobhna, Garrett, Theo, Ibanez-Ventoso, Carolina, Hope, June, Kish, Jason L, Guo, Max, Lithgow, Gordon J., Driscoll, Monica, Phillips, Patrick C.
Publicado 2017