Functional Amyloidogenesis and Cytotoxicity—Insights into Biology and Pathology

por Fowler, Douglas M., Kelly, Jeffery W.
Publicado 2012

Keeping up with the genomes: scaling genomic variant interpretation

por Rehm, Heidi L., Fowler, Douglas M.
Publicado 2019

Highlighting rare disease research with a GENETICS and G3 series on genetic models of rare diseases

por Hieter, Philip, Andrews, Brenda, Fowler, Douglas, Bellen, Hugo
Publicado 2023

Highlighting rare disease research with a GENETICS and G3 series on genetic models of rare diseases

por Hieter, Philip, Andrews, Brenda, Fowler, Douglas, Bellen, Hugo
Publicado 2023

Comprehensive exploration of the translocation, stability and substrate recognition requirements in VIM-2 lactamase

por Chen, John Z, Fowler, Douglas M, Tokuriki, Nobuhiko
Publicado 2020

Partial Restoration of Mutant Enzyme Homeostasis in Three Distinct Lysosomal Storage Disease Cell Lines by Altering Calcium Homeostasis

por Mu, Ting-Wei, Fowler, Douglas M, Kelly, Jeffery W
Publicado 2008

A platform for functional assessment of large variant libraries in mammalian cells

por Matreyek, Kenneth A., Stephany, Jason J., Fowler, Douglas M.
Publicado 2017

Analysis of Large-Scale Mutagenesis Data To Assess the Impact of Single Amino Acid Substitutions

por Gray, Vanessa E., Hause, Ronald J., Fowler, Douglas M.
Publicado 2017

Enrich: software for analysis of protein function by enrichment and depletion of variants

por Fowler, Douglas M., Araya, Carlos L., Gerard, Wayne, Fields, Stanley
Publicado 2011

Integrating thousands of PTEN variant activity and abundance measurements reveals variant subgroups and new dominant negatives in cancers

por Matreyek, Kenneth A., Stephany, Jason J., Ahler, Ethan, Fowler, Douglas M.
Publicado 2021

Pharmacogenomics of CYP2C9: Functional and Clinical Considerations(†)

por Daly, Ann K., Rettie, Allan E., Fowler, Douglas M., Miners, John O.
Publicado 2017

Rheostatic Control of Cas9-Mediated DNA Double Strand Break (DSB) Generation and Genome Editing

por Rose, John C., Stephany, Jason J., Wei, Cindy T., Fowler, Douglas M., Maly, Dustin J.
Publicado 2017

An improved platform for functional assessment of large protein libraries in mammalian cells

por Matreyek, Kenneth A, Stephany, Jason J, Chiasson, Melissa A, Hasle, Nicholas, Fowler, Douglas M
Publicado 2020

Functional Amyloid Formation within Mammalian Tissue

por Fowler, Douglas M, Koulov, Atanas V, Alory-Jost, Christelle, Marks, Michael S, Balch, William E, Kelly, Jeffery W
Publicado 2006

A statistical framework for analyzing deep mutational scanning data

por Rubin, Alan F., Gelman, Hannah, Lucas, Nathan, Bajjalieh, Sandra M., Papenfuss, Anthony T., Speed, Terence P., Fowler, Douglas M.
Publicado 2017

Correction to: A statistical framework for analyzing deep mutational scanning data

por Rubin, Alan F., Gelman, Hannah, Lucas, Nathan, Bajjalieh, Sandra M., Papenfuss, Anthony T., Speed, Terence P., Fowler, Douglas M.
Publicado 2018

High Resolution Mapping of Protein Sequence–Function Relationships

por Fowler, Douglas M., Araya, Carlos L., Fleishman, Sarel J., Kellogg, Elizabeth H., Stephany, Jason J., Baker, David, Fields, Stanley
Publicado 2010

Elucidating the Molecular Determinants of Aβ Aggregation with Deep Mutational Scanning

por Gray, Vanessa E., Sitko, Katherine, Kameni, Floriane Z. Ngako, Williamson, Miriam, Stephany, Jason J., Hasle, Nicholas, Fowler, Douglas M.
Publicado 2019

MaveRegistry: a collaboration platform for multiplexed assays of variant effect

por Kuang, Da, Weile, Jochen, Kishore, Nishka, Nguyen, Maria, Rubin, Alan F, Fields, Stanley, Fowler, Douglas M, Roth, Frederick P
Publicado 2021

MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect

por Esposito, Daniel, Weile, Jochen, Shendure, Jay, Starita, Lea M., Papenfuss, Anthony T., Roth, Frederick P., Fowler, Douglas M., Rubin, Alan F.
Publicado 2019