How quickly can we predict trimethoprim resistance using alchemical free energy methods?

por Fowler, Philip W.
Publicado 2020

Inclusion of minor alleles improves catalogue-based prediction of fluoroquinolone resistance in Mycobacterium tuberculosis

por Brankin, Alice E, Fowler, Philip W
Publicado 2023

The pore of voltage-gated potassium ion channels is strained when closed

por Fowler, Philip W., Sansom, Mark S. P.
Publicado 2013

Predicting Resistance Is (Not) Futile

por Brankin, Alice E., Fowler, Philip W.
Publicado 2019

Predicting antibiotic resistance in complex protein targets using alchemical free energy methods

por Brankin, Alice E., Fowler, Philip W.
Publicado 2022

NRas slows the rate at which a model lipid bilayer phase separates

por Jefferys, Elizabeth, Sansom, Mark S. P., Fowler, Philip W.
Publicado 2014

Detailed Examination of a Single Conduction Event in a Potassium Channel

por Fowler, Philip W., Beckstein, Oliver, Abad, Enrique, Sansom, Mark S. P.
Publicado 2013

Energetics of Multi-Ion Conduction Pathways in Potassium Ion Channels

por Fowler, Philip W., Abad, Enrique, Beckstein, Oliver, Sansom, Mark S. P.
Publicado 2013

Effect of the Southeast Asian Ovalocytosis Deletion on the Conformational Dynamics of Signal-Anchor Transmembrane Segment 1 of Red Cell Anion Exchanger 1 (AE1, Band 3, or SLC4A1)

por Fowler, Philip W., Sansom, Mark S. P., Reithmeier, Reinhart A. F.
Publicado 2017

Productivity in relation to organization of a surgical department: a retrospective observational study

por Eriksson, Johan, Fowler, Philip, Appelblad, Micael, Lindholm, Lena, Sund, Malin
Publicado 2022

Flexible Gates Generate Occluded Intermediates in the Transport Cycle of LacY()

por Stelzl, Lukas S., Fowler, Philip W., Sansom, Mark S.P., Beckstein, Oliver
Publicado 2014

ReadItAndKeep: rapid decontamination of SARS-CoV-2 sequencing reads

por Hunt, Martin, Swann, Jeremy, Constantinides, Bede, Fowler, Philip W, Iqbal, Zamin
Publicado 2022

Roles of Interleaflet Coupling and Hydrophobic Mismatch in Lipid Membrane Phase-Separation Kinetics

por Fowler, Philip W., Williamson, John J., Sansom, Mark S. P., Olmsted, Peter D.
Publicado 2016

Alchembed: A Computational Method for Incorporating Multiple Proteins into Complex Lipid Geometries

por Jefferys, Elizabeth, Sands, Zara A., Shi, Jiye, Sansom, Mark S. P., Fowler, Philip W.
Publicado 2015

Accurate Prediction of Ligand Affinities for a Proton-Dependent Oligopeptide Transporter

por Samsudin, Firdaus, Parker, Joanne L., Sansom, Mark S.P., Newstead, Simon, Fowler, Philip W.
Publicado 2016

Membrane stiffness is modified by integral membrane proteins

por Fowler, Philip W., Hélie, Jean, Duncan, Anna, Chavent, Matthieu, Koldsø, Heidi, Sansom, Mark S. P.
Publicado 2016

H Bonding at the Helix-Bundle Crossing Controls Gating in Kir Potassium Channels

por Rapedius, Markus, Fowler, Philip W., Shang, Lijun, Sansom, Mark S.P., Tucker, Stephen J., Baukrowitz, Thomas
Publicado 2007

Alternating access mechanism in the POT family of oligopeptide transporters

por Solcan, Nicolae, Kwok, Jane, Fowler, Philip W, Cameron, Alexander D, Drew, David, Iwata, So, Newstead, Simon
Publicado 2012

Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target

por Adams, Oliver, Deme, Justin C., Parker, Joanne L., Fowler, Philip W., Lea, Susan M., Newstead, Simon
Publicado 2021

Protein crowding and lipid complexity influence the nanoscale dynamic organization of ion channels in cell membranes

por Duncan, Anna L., Reddy, Tyler, Koldsø, Heidi, Hélie, Jean, Fowler, Philip W., Chavent, Matthieu, Sansom, Mark S. P.
Publicado 2017