Paraspeckles: nuclear bodies built on long noncoding RNA

por Bond, Charles S., Fox, Archa H.
Publicado 2009

Nuclear processes controlled by molecular machines

por Fox, Archa H, Lamond, Angus I
Publicado 2002

The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffold

por Knott, Gavin J., Bond, Charles S., Fox, Archa H.
Publicado 2016

Matrix stiffness-sensitive long noncoding RNA NEAT1 seeded paraspeckles in cancer cells

por Todorovski, Vanja, Fox, Archa H., Choi, Yu Suk
Publicado 2020

Functional dissection of NEAT1 using genome editing reveals substantial localization of the NEAT1_1 isoform outside paraspeckles

por Li, Ruohan, Harvey, Alan R., Hodgetts, Stuart I., Fox, Archa H.
Publicado 2017

The Non-Coding RNA Journal Club: Highlights on Recent Papers-8

por Tarallo, Sonia, Pardini, Barbara, Fox, Archa H., Ingram, Hayley, Taccioli, Cristian, Taube, Joseph H., Mani, Sendurai A.
Publicado 2021

ALS-linked FUS mutations confer loss and gain of function in the nucleus by promoting excessive formation of dysfunctional paraspeckles

por An, Haiyan, Skelt, Lucy, Notaro, Antonietta, Highley, J. Robin, Fox, Archa H., La Bella, Vincenzo, Buchman, Vladimir L., Shelkovnikova, Tatyana A.
Publicado 2019

Genome-wide analysis of long noncoding RNA stability

por Clark, Michael B., Johnston, Rebecca L., Inostroza-Ponta, Mario, Fox, Archa H., Fortini, Ellen, Moscato, Pablo, Dinger, Marcel E., Mattick, John S.
Publicado 2012

Confined environments induce polarized paraspeckle condensates

por Todorovski, Vanja, McCluggage, Finn, Li, Yixuan, Meid, Annika, Spatz, Joachim P., Holle, Andrew W., Fox, Archa H., Choi, Yu Suk
Publicado 2023

The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation

por Lee, Mihwa, Sadowska, Agata, Bekere, Indra, Ho, Diwei, Gully, Benjamin S., Lu, Yanling, Iyer, K. Swaminathan, Trewhella, Jill, Fox, Archa H., Bond, Charles S.
Publicado 2015

NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

por Hirose, Tetsuro, Virnicchi, Giorgio, Tanigawa, Akie, Naganuma, Takao, Li, Ruohan, Kimura, Hiroshi, Yokoi, Takahide, Nakagawa, Shinichi, Bénard, Marianne, Fox, Archa H., Pierron, Gérard
Publicado 2014

Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains

por Lee, Pei Wen, Marshall, Andrew C., Knott, Gavin J., Kobelke, Simon, Martelotto, Luciano, Cho, Ellie, McMillan, Paul J., Lee, Mihwa, Bond, Charles S., Fox, Archa H.
Publicado 2022

Structural basis of dimerization and nucleic acid binding of human DBHS proteins NONO and PSPC1

por Knott, Gavin J, Chong, Yee Seng, Passon, Daniel M, Liang, Xue-hai, Deplazes, Evelyne, Conte, Maria R, Marshall, Andrew C, Lee, Mihwa, Fox, Archa H, Bond, Charles S
Publicado 2021

Protocadherin 19 (PCDH19) interacts with paraspeckle protein NONO to co-regulate gene expression with estrogen receptor alpha (ERα)

por Pham, Duyen H., Tan, Chuan C., Homan, Claire C., Kolc, Kristy L., Corbett, Mark A., McAninch, Dale, Fox, Archa H., Thomas, Paul Q., Kumar, Raman, Gecz, Jozef
Publicado 2017

NONO enhances mRNA processing of super‐enhancer‐associated GATA2 and HAND2 genes in neuroblastoma

por Zhang, Song, Cooper, Jack AL, Chong, Yee Seng, Naveed, Alina, Mayoh, Chelsea, Jayatilleke, Nisitha, Liu, Tao, Amos, Sebastian, Kobelke, Simon, Marshall, Andrew C, Meers, Oliver, Choi, Yu Suk, Bond, Charles S, Fox, Archa H
Publicado 2022

Single Stranded Fully Modified-Phosphorothioate Oligonucleotides can Induce Structured Nuclear Inclusions, Alter Nuclear Protein Localization and Disturb the Transcriptome In Vitro

por Flynn, Loren L., Li, Ruohan, Pitout, Ianthe L., Aung-Htut, May T., Larcher, Leon M., Cooper, Jack A. L., Greer, Kane L., Hubbard, Alysia, Griffiths, Lisa, Bond, Charles S., Wilton, Steve D., Fox, Archa H., Fletcher, Sue
Publicado 2022

Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles

por Hennig, Sven, Kong, Geraldine, Mannen, Taro, Sadowska, Agata, Kobelke, Simon, Blythe, Amanda, Knott, Gavin J., Iyer, K. Swaminathan, Ho, Diwei, Newcombe, Estella A., Hosoki, Kana, Goshima, Naoki, Kawaguchi, Tetsuya, Hatters, Danny, Trinkle-Mulcahy, Laura, Hirose, Tetsuro, Bond, Charles S., Fox, Archa H.
Publicado 2015

Caveolin‐1‐driven membrane remodelling regulates hnRNPK‐mediated exosomal microRNA sorting in cancer

por Robinson, Harley, Ruelcke, Jayde E., Lewis, Amanda, Bond, Charles S., Fox, Archa H., Bharti, Vandhana, Wani, Shivangi, Cloonan, Nicole, Lai, Andrew, Margolin, David, Li, Li, Salomon, Carlos, Richards, Renée S., Farrell, Aine, Gardiner, Robert A., Parton, Robert G., Cristino, Alexandre S., Hill, Michelle M.
Publicado 2021

Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development

por Thomas-Jinu, Swapna, Gordon, Patricia M., Fielding, Triona, Taylor, Richard, Smith, Bradley N., Snowden, Victoria, Blanc, Eric, Vance, Caroline, Topp, Simon, Wong, Chun-Hao, Bielen, Holger, Williams, Kelly L., McCann, Emily P., Nicholson, Garth A., Pan-Vazquez, Alejandro, Fox, Archa H., Bond, Charles S., Talbot, William S., Blair, Ian P., Shaw, Christopher E., Houart, Corinne
Publicado 2017

Non-nuclear Pool of Splicing Factor SFPQ Regulates Axonal Transcripts Required for Normal Motor Development

por Thomas-Jinu, Swapna, Gordon, Patricia M., Fielding, Triona, Taylor, Richard, Smith, Bradley N., Snowden, Victoria, Blanc, Eric, Vance, Caroline, Topp, Simon, Wong, Chun-Hao, Bielen, Holger, Williams, Kelly L., McCann, Emily P., Nicholson, Garth A., Pan-Vazquez, Alejandro, Fox, Archa H., Bond, Charles S., Talbot, William S., Blair, Ian P., Shaw, Christopher E., Houart, Corinne
Publicado 2017