A Multiscale Agent-Based in silico Model of Liver Fibrosis Progression

por Dutta-Moscato, Joyeeta, Solovyev, Alexey, Mi, Qi, Nishikawa, Taichiro, Soto-Gutierrez, Alejandro, Fox, Ira J., Vodovotz, Yoram
Publicado 2014

Single Liver Lobe Repopulation with Wildtype Hepatocytes Using Regional Hepatic Irradiation Cures Jaundice in Gunn Rats

por Zhou, Hongchao, Dong, Xinyuan, Kabarriti, Rafi, Chen, Yong, Avsar, Yesim, Wang, Xia, Ding, Jianqiang, Liu, Laibin, Fox, Ira J., Roy-Chowdhury, Jayanta, Roy-Chowdhury, Namita, Guha, Chandan
Publicado 2012

Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency

por Li, Yanfeng, Guha, Chandan, Asp, Patrik, Wang, Xia, Tchaikovskya, Tatyana L., Kim, Kenneth, Mendel, Matthew, Cost, Gregory J., Perlmutter, David H., Roy-Chowdhury, Namita, Fox, Ira J., Conway, Anthony, Roy-Chowdhury, Jayanta
Publicado 2023

Hepatocyte Nuclear Factor 4 alpha 2 Messenger RNA Reprograms Liver‐Enriched Transcription Factors and Functional Proteins in End‐Stage Cirrhotic Human Hepatocytes

por Tafaleng, Edgar N., Mukherjee, Amitava, Bell, Aaron, Morita, Kazutoyo, Guzman‐Lepe, Jorge, Haep, Nils, Florentino, Rodrigo M., Diaz‐Aragon, Ricardo, Frau, Carla, Ostrowska, Alina, Schultz, Joshua R., Martini, Paolo G. V., Soto‐Gutierrez, Alejandro, Fox, Ira J.
Publicado 2021

Liver‐enriched transcription factor expression relates to chronic hepatic failure in humans

por Guzman‐Lepe, Jorge, Cervantes‐Alvarez, Eduardo, Collin de l'Hortet, Alexandra, Wang, Yang, Mars, Wendy M., Oda, Yoshinao, Bekki, Yuki, Shimokawa, Masahiro, Wang, Huanlin, Yoshizumi, Tomoharu, Maehara, Yoshihiko, Bell, Aaron, Fox, Ira J., Takeishi, Kazuki, Soto‐Gutierrez, Alejandro
Publicado 2018

All-human microphysical model of metastasis therapy

por Wheeler, Sarah E, Borenstein, Jeffrey T, Clark, Amanda M, Ebrahimkhani, Mohammad R, Fox, Ira J, Griffith, Linda, Inman, Walker, Lauffenburger, Douglas, Nguyen, Transon, Pillai, Venkateswaran C, Prantil-Baun, Rachelle, Stolz, Donna B, Taylor, Donald, Ulrich, Theresa, Venkataramanan, Raman, Wells, Alan, Young, Carissa
Publicado 2013

Amelioration of Hyperbilirubinemia in Gunn Rats after Transplantation of Human Induced Pluripotent Stem Cell-Derived Hepatocytes

por Chen, Yong, Li, Yanfeng, Wang, Xia, Zhang, Wei, Sauer, Vanessa, Chang, Chan-Jung, Han, Bing, Tchaikovskaya, Tatyana, Avsar, Yesim, Tafaleng, Edgar, Madhusudana Girija, Sanal, Tar, Krisztina, Polgar, Zsuzsanna, Strom, Stephen, Bouhassira, Eric E., Guha, Chandan, Fox, Ira J., Roy-Chowdhury, Jayanta, Roy-Chowdhury, Namita
Publicado 2015

A non-human primate model of acute liver failure suitable for testing liver support systems

por Kalsi, Ranjeet S., Ostrowska, Alina, Olson, Adam, Quader, Mubina, Deutsch, Melvin, Arbujas-Silva, Norma J., Symmonds, Jen, Soto-Gutierrez, Alejandro, Crowley, John J., Reyes-Mugica, Miguel, Sanchez-Guerrero, Giselle, Jaeschke, Hartmut, Amiot, Bruce P., Cascalho, Marilia, Nyberg, Scott L., Platt, Jeffrey L., Tafaleng, Edgar N., Fox, Ira J.
Publicado 2022

Biofabrication of synthetic human liver tissue with advanced programmable functions

por Florentino, Rodrigo M., Morita, Kazutoyo, Haep, Nils, Motomura, Takashi, Diaz-Aragon, Ricardo, Faccioli, Lanuza A.P., Collin de l’Hortet, Alexandra, Cetin, Zeliha, Frau, Carla, Vernetti, Lawrence, Amler, Anna-Klara, Thomas, Alexander, Lam, Tobias, Kloke, Lutz, Takeishi, Kazuki, Taylor, D. Lansing, Fox, Ira J., Soto-Gutierrez, Alejandro
Publicado 2022

Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans

por Florentino, Rodrigo M., Fraunhoffer, Nicolas A., Morita, Kazutoyo, Takeishi, Kazuki, Ostrowska, Alina, Achreja, Abhinav, Animasahun, Olamide, Haep, Nils, Arazov, Shohrat, Agarwal, Nandini, Collin de l'Hortet, Alexandra, Guzman‐Lepe, Jorge, Tafaleng, Edgar N., Mukherjee, Amitava, Troy, Kris, Banerjee, Swati, Paranjpe, Shirish, Michalopoulos, George K., Bell, Aaron, Nagrath, Deepak, Hainer, Sarah J., Fox, Ira J., Soto‐Gutierrez, Alejandro
Publicado 2020