First‐in‐Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability...

por Fox, Jonathan C., Hellawell, Jennifer L., Rao, Satish, O'Reilly, Terry, Lumpkin, Rick, Jernelius, Jesper, Gretler, Daniel, Sinha, Uma
Publicado 2019

A Phase 2B, Open-Label, Dose-Ranging Study of Encaleret (CLTX-305) in Autosomal Dominant Hypocalcemia Type 1 (ADH1)

por Gafni, Rachel Ilana, Hartley, Iris Ruth, Roszko, Kelly Lauter, Nemeth, Edward F, Pozo, Karen A, Sani-Grosso, Ramei, Sridhar, Ananth, Fox, Jonathan C, Collins, Michael T
Publicado 2021

Autosomal Dominant Hypocalcemia Type 1: A Systematic Review

por Roszko, Kelly L, Stapleton Smith, Lyndsay M, Sridhar, Ananth V, Roberts, Mary Scott, Hartley, Iris R, Gafni, Rachel I, Collins, Michael T, Fox, Jonathan C, Nemeth, Edward F
Publicado 2022

The Effects of Encaleret (CLTX-305) on Mineral Physiology in Autosomal Dominant Hypocalcemia Type 1 (ADH1) Demonstrate Proof-of-Concept: Early Results From an Ongoing Phase 2b, Ope...

por Gafni, Rachel Ilana, Hartley, Iris Ruth, Roszko, Kelly Lauter, Nemeth, Edward F, Pozo, Karen A, Sani-Grosso, Ramei, Sridhar, Ananth, Kennedy, William D, Fox, Jonathan C, Collins, Michael T
Publicado 2021

Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights From the Sarcomeric Human Cardiomyopathy Registry (SHaRe)

por Ho, Carolyn Y., Day, Sharlene M., Ashley, Euan A., Michels, Michelle, Pereira, Alexandre C., Jacoby, Daniel, Cirino, Allison L., Fox, Jonathan C., Lakdawala, Neal K., Ware, James S., Caleshu, Colleen A., Helms, Adam S., Colan, Steven D., Girolami, Francesca, Cecchi, Franco, Seidman, Christine E., Sajeev, Gautam, Signorovitch, James, Green, Eric M., Olivotto, Iacopo
Publicado 2018