TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth

por Shah, Anant, Melhuish, Tiffany A., Fox, Todd E., Frierson, Henry F., Wotton, David
Publicado 2019

STAT3 mediates C6-ceramide-induced cell death in chronic lymphocytic leukemia

por Doshi, Ushma A, Shaw, Jeremy, Fox, Todd E, Claxton, David F, Loughran, Thomas P, Kester, Mark
Publicado 2017

Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in T. gondii infection-induced cachexia

por Feng, Tzu-Yu, Melchor, Stephanie J., Zhao, Xiao-Yu, Ghumman, Haider, Kester, Mark, Fox, Todd E., Ewald, Sarah E.
Publicado 2023

Ceramide Nanoliposomes as Potential Therapeutic Reagents for Asthma

por Sakae, Harumi, Ogiso, Yuri, Matsuda, Masaya, Shimora, Hayato, Deering, Tye, Fox, Todd E., Kester, Mark, Nabe, Takeshi, Kitatani, Kazuyuki
Publicado 2023

Altered Sphingolipid Metabolism in Patients with Metastatic Pancreatic Cancer

por Jiang, Yixing, DiVittore, Nicole A., Young, Megan M, Jia, Zhiliang, Xie, Keping, Ritty, Timothy M., Kester, Mark, Fox, Todd E.
Publicado 2013

Role of SPTSSB-Regulated de Novo Sphingolipid Synthesis in Prostate Cancer Depends on Androgen Receptor Signaling

por Costa-Pinheiro, Pedro, Heher, Abigail, Raymond, Michael H., Jividen, Kasey, Shaw, Jeremy JP., Paschal, Bryce M., Walker, Susan J., Fox, Todd E., Kester, Mark
Publicado 2020

Childhood growth and neurocognition are associated with distinct sets of metabolites

por Moreau, G. Brett, Ramakrishnan, Girija, Cook, Heather L., Fox, Todd E., Nayak, Uma, Ma, Jennie Z., Colgate, E. Ross, Kirkpatrick, Beth D., Haque, Rashidul, Petri, William A.
Publicado 2019

Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations

por Olson, Kristine C., Moosic, Katharine B., Jones, Marieke K., Larkin, Paige M. K., Olson, Thomas L., Toro, Mariella F., Fox, Todd E., Feith, David J., Loughran, Thomas P.
Publicado 2020

Glucosylceramide synthase maintains influenza virus entry and infection

por Drews, Kelly, Calgi, Michael P., Harrison, William Casey, Drews, Camille M., Costa-Pinheiro, Pedro, Shaw, Jeremy Joseph Porter, Jobe, Kendra A., Han, John D., Fox, Todd E., White, Judith M., Kester, Mark
Publicado 2020

C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia

por Ryland, Lindsay K., Doshi, Ushma A., Shanmugavelandy, Sriram S., Fox, Todd E., Aliaga, Cesar, Broeg, Kathleen, Baab, Kendall Thomas, Young, Megan, Khan, Osman, Haakenson, Jeremy K., Jarbadan, Nancy Ruth, Liao, Jason, Wang, Hong-Gang, Feith, David J., Loughran Jr, Thomas P., Liu, Xin, Kester, Mark
Publicado 2013

Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia

por Khokhlatchev, Andrei V., Sharma, Arati, Deering, Tye G., Shaw, Jeremy J. P., Costa‐Pinheiro, Pedro, Golla, Upendarrao, Annageldiyev, Charyguly, Cabot, Myles C., Conaway, Mark R., Tan, Su‐Fern, Ung, Johnson, Feith, David J., Loughran, Thomas P., Claxton, David F., Fox, Todd E., Kester, Mark
Publicado 2022

Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes

por Paudel, B. Bishal, Tan, Su-Fern, Fox, Todd E., Ung, Johnson, Shaw, Jeremy, Dunton, Wendy, Lee, Irene, Sharma, Arati, Viny, Aaron D., Barth, Brian M., Tallman, Martin S., Cabot, Myles, Garrett-Bakelman, Francine E., Levine, Ross L., Kester, Mark, Claxton, David, Feith, David J., Janes, Kevin A., Loughran, Thomas P.
Publicado 2023

Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloi...

por Fisher-Wellman, Kelsey H., Kassai, Miki, Hagen, James T., Neufer, P. Darrell, Kester, Mark, Loughran, Thomas P., Chalfant, Charles E., Feith, David J., Tan, Su-Fern, Fox, Todd E., Ung, Johnson, Fabrias, Gemma, Abad, Jose’ Luis, Sharma, Arati, Golla, Upendarrao, Claxton, David F., Shaw, Jeremy J. P., Bhowmick, Debajit, Cabot, Myles C.
Publicado 2023

Acid ceramidase is upregulated in AML and represents a novel therapeutic target

por Tan, Su-Fern, Liu, Xin, Fox, Todd E., Barth, Brian M., Sharma, Arati, Turner, Stephen D., Awwad, Andy, Dewey, Alden, Doi, Kenichiro, Spitzer, Barbara, Shah, Mithun Vinod, Morad, Samy A.F., Desai, Dhimant, Amin, Shantu, Zhu, Junjia, Liao, Jason, Yun, Jong, Kester, Mark, Claxton, David F., Wang, Hong-Gang, Cabot, Myles C., Schuchman, Edward H., Levine, Ross L., Feith, David J., Loughran, Thomas P.
Publicado 2016