FAK and talin: Who is taking whom to the integrin engagement party?

por Serrels, Bryan, Frame, Margaret C.
Publicado 2012

The ROCKs on which tumour cells thrive

por Wilkinson, Simon, Frame, Margaret C
Publicado 2016

Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts

por Byron, Adam, Frame, Margaret C
Publicado 2016

p70S6K is regulated by focal adhesion kinase and is required for Src-selective autophagy

por Sandilands, Emma, Schoenherr, Christina, Frame, Margaret C.
Publicado 2015

Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo

por Lahlou, Hicham, Sanguin-Gendreau, Virginie, Frame, Margaret C, Muller, William J
Publicado 2012

FAK Deletion Promotes p53-Mediated Induction of p21, DNA-Damage Responses and Radio-Resistance in Advanced Squamous Cancer Cells

por Graham, Kathryn, Moran-Jones, Kim, Sansom, Owen J., Brunton, Valerie G., Frame, Margaret C.
Publicado 2011

Kindlin1 regulates microtubule function to ensure normal mitosis

por Patel, Hitesh, Stavrou, Ifigeneia, Shrestha, Roshan L., Draviam, Viji, Frame, Margaret C., Brunton, Valerie G.
Publicado 2016

The IpaC Carboxyterminal Effector Domain Mediates Src-Dependent Actin Polymerization during Shigella Invasion of Epithelial Cells

por Mounier, Joëlle, Popoff, Michel R., Enninga, Jost, Frame, Margaret C., Sansonetti, Philippe J., Van Nhieu, Guy Tran
Publicado 2009

Kindlin-1 regulates IL-6 secretion and modulates the immune environment in breast cancer models

por Webb, Emily R, Dodd, Georgia L, Noskova, Michaela, Bullock, Esme, Muir, Morwenna, Frame, Margaret C, Serrels, Alan, Brunton, Valerie G
Publicado 2023

Eps8 controls Src- and FAK-dependent phenotypes in squamous carcinoma cells

por Schoenherr, Christina, Serrels, Bryan, Proby, Charlotte, Cunningham, Debbie L., Findlay, Jane E., Baillie, George S., Heath, John K., Frame, Margaret C.
Publicado 2014

c-Src drives intestinal regeneration and transformation

por Cordero, Julia B, Ridgway, Rachel A, Valeri, Nicola, Nixon, Colin, Frame, Margaret C, Muller, William J, Vidal, Marcos, Sansom, Owen J
Publicado 2014

Diversity of Matriptase Expression Level and Function in Breast Cancer

por Welman, Arkadiusz, Sproul, Duncan, Mullen, Peter, Muir, Morwenna, Kinnaird, Andrew R., Harrison, David J., Faratian, Dana, Brunton, Valerie G., Frame, Margaret C.
Publicado 2012

Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks

por Schoenherr, Christina, Byron, Adam, Sandilands, Emma, Paliashvili, Ketevan, Baillie, George S, Garcia-Munoz, Amaya, Valacca, Cristina, Cecconi, Francesco, Serrels, Bryan, Frame, Margaret C
Publicado 2017

FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs

por Griffith, Billie G. C., Upstill-Goddard, Rosanna, Brunton, Holly, Grimes, Graeme R., Biankin, Andrew V., Serrels, Bryan, Byron, Adam, Frame, Margaret C.
Publicado 2021

Quantitative proteomics identifies tumour matrisome signatures in patients with non-small cell lung cancer

por Titmarsh, Helen F., von Kriegsheim, Alex, Wills, Jimi C., O’Connor, Richard A., Dhaliwal, Kevin, Frame, Margaret C., Pattle, Samuel B., Dorward, David A., Byron, Adam, Akram, Ahsan R.
Publicado 2023

ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival

por Kanellos, Georgios, Zhou, Jing, Patel, Hitesh, Ridgway, Rachel A., Huels, David, Gurniak, Christine B., Sandilands, Emma, Carragher, Neil O., Sansom, Owen J., Witke, Walter, Brunton, Valerie G., Frame, Margaret C.
Publicado 2015

Rapid Discovery and Structure–Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity...

por Fraser, Craig, Dawson, John C., Dowling, Reece, Houston, Douglas R., Weiss, Jason T., Munro, Alison F., Muir, Morwenna, Harrington, Lea, Webster, Scott P., Frame, Margaret C., Brunton, Valerie G., Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier
Publicado 2016

Characterisation of a nucleo-adhesome

por Byron, Adam, Griffith, Billie G. C., Herrero, Ana, Loftus, Alexander E. P., Koeleman, Emma S., Kogerman, Linda, Dawson, John C., McGivern, Niamh, Culley, Jayne, Grimes, Graeme R., Serrels, Bryan, von Kriegsheim, Alex, Brunton, Valerie G., Frame, Margaret C.
Publicado 2022

LKB1 Haploinsufficiency Cooperates With Kras to Promote Pancreatic Cancer Through Suppression of p21-Dependent Growth Arrest

por Morton, Jennifer P., Jamieson, Nigel B., Karim, Saadia A., Athineos, Dimitris, Ridgway, Rachel A., Nixon, Colin, McKay, Colin J., Carter, Ross, Brunton, Valerie G., Frame, Margaret C., Ashworth, Alan, Oien, Karin A., Evans, T.R. Jeffry, Sansom, Owen J.
Publicado 2010

The MacBlue Binary Transgene (csf1r-gal4VP16/UAS-ECFP) Provides a Novel Marker for Visualisation of Subsets of Monocytes, Macrophages and Dendritic Cells and Responsiveness to CSF1...

por Sauter, Kristin A., Pridans, Clare, Sehgal, Anuj, Bain, Calum C., Scott, Charlotte, Moffat, Lindsey, Rojo, Rocío, Stutchfield, Ben M., Davies, Claire L., Donaldson, David S., Renault, Kathleen, McColl, Barry W., Mowat, Alan M., Serrels, Alan, Frame, Margaret C., Mabbott, Neil A., Hume, David A.
Publicado 2014