Steric Shielding of Surface Epitopes and Impaired Immune Recognition Induced by the Ebola Virus Glycoprotein

por Francica, Joseph R., Varela-Rohena, Angel, Medvec, Andrew, Plesa, Gabriela, Riley, James L., Bates, Paul
Publicado 2010

Chinese hamster ovary cell lines selected for resistance to ebolavirus glycoprotein mediated infection are defective for NPC1 expression

por Haines, Kathleen M., Vande Burgt, Nathan H., Francica, Joseph R., Kaletsky, Rachel L., Bates, Paul
Publicado 2012

Structure and Diversity of the Rhesus Macaque Immunoglobulin Loci through Multiple De Novo Genome Assemblies

por Ramesh, Akshaya, Darko, Sam, Hua, Axin, Overman, Glenn, Ransier, Amy, Francica, Joseph R., Trama, Ashley, Tomaras, Georgia D., Haynes, Barton F., Douek, Daniel C., Kepler, Thomas B.
Publicado 2017

The P. falciparum CSP repeat region contains three distinct epitopes required for protection by antibodies in vivo

por Flores-Garcia, Yevel, Wang, Lawrence T., Park, Minah, Asady, Beejan, Idris, Azza H., Kisalu, Neville K., Muñoz, Christian, Pereira, Lais S., Francica, Joseph R., Seder, Robert A., Zavala, Fidel
Publicado 2021

Protective effects of combining monoclonal antibodies and vaccines against the Plasmodium falciparum circumsporozoite protein

por Wang, Lawrence T., Pereira, Lais S., Kiyuka, Patience K., Schön, Arne, Kisalu, Neville K., Vistein, Rachel, Dillon, Marlon, Bonilla, Brian G., Molina-Cruz, Alvaro, Barillas-Mury, Carolina, Tan, Joshua, Idris, Azza H., Francica, Joseph R., Seder, Robert A.
Publicado 2021

Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention

por Kisalu, Neville K., Pereira, Lais D., Ernste, Keenan, Flores-Garcia, Yevel, Idris, Azza H., Asokan, Mangaiarkarasi, Dillon, Marlon, MacDonald, Scott, Shi, Wei, Chen, Xuejun, Pegu, Amarendra, Schön, Arne, Zavala, Fidel, Balazs, Alejandro B., Francica, Joseph R., Seder, Robert A.
Publicado 2021

Cytotoxicity of human antibodies targeting the circumsporozoite protein is amplified by 3D substrate and correlates with protection

por Aguirre-Botero, Manuela C., Wang, Lawrence T., Formaglio, Pauline, Aliprandini, Eduardo, Thiberge, Jean-Michel, Schön, Arne, Flores-Garcia, Yevel, Mathis-Torres, Shamika, Flynn, Barbara J., da Silva Pereira, Lais, Le Duff, Yann, Hurley, Mathew, Nacer, Adéla, Bowyer, Paul W., Zavala, Fidel, Idris, Azza H., Francica, Joseph R., Seder, Robert A., Amino, Rogerio
Publicado 2023

1355. The SARS-CoV-2 Monoclonal Antibody AZD3152 Potently Neutralizes Historical and Emerging Variants and is Being Developed for the Prevention and Treatment of COVID-19 in High-r...

por Francica, Joseph R, Cai, Yingyun, Diallo, Seme, Rosenthal, Kim, Ren, Kuishu, Flores, Daniel J, Dippel, Andrew, Wu, Yuling, Chen, Xiaoru, Cantu, Erin, Choudhary, Rakesh, Sulikowski, Michal, Adissu, Hibret, Chawla, Bhavna, Kar, Swagata, van Dyk, Nydia, Oganesyan, Vaheh, Rajan, Saravanan, Ryan, Patricia C, Loo, Yueh-Ming, Cohen, Taylor, Esser, Mark T, Blair, Wade
Publicado 2023

Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates

por Francica, Joseph R., Laga, Richard, Lynn, Geoffrey M., Mužíková, Gabriela, Androvič, Ladislav, Aussedat, Baptiste, Walkowicz, William E., Padhan, Kartika, Ramirez-Valdez, Ramiro Andrei, Parks, Robert, Schmidt, Stephen D., Flynn, Barbara J., Tsybovsky, Yaroslav, Stewart-Jones, Guillaume B. E., Saunders, Kevin O., Baharom, Faezzah, Petrovas, Constantinos, Haynes, Barton F., Seder, Robert A.
Publicado 2019

Design of Alphavirus Virus-Like Particles Presenting Circumsporozoite Junctional Epitopes That Elicit Protection against Malaria

por Francica, Joseph R., Shi, Wei, Chuang, Gwo-Yu, Chen, Steven J., Da Silva Pereira, Lais, Farney, S. Katie, Flynn, Barbara J., Ou, Li, Stephens, Tyler, Tsybovsky, Yaroslav, Wang, Lawrence T., Anderson, Alexander, Beck, Zoltan, Dillon, Marlon, Idris, Azza H., Hurlburt, Nicholas, Liu, Tracy, Zhang, Baoshan, Alving, Carl R., Matyas, Gary R., Pancera, Marie, Mascola, John R., Kwong, Peter D., Seder, Robert A.
Publicado 2021

Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01(B) malaria vaccine

por Nielsen, Carolyn M., Barrett, Jordan R., Davis, Christine, Fallon, Jonathan K., Goh, Cyndi, Michell, Ashlin R., Griffin, Catherine, Kwok, Andrew, Loos, Carolin, Darko, Samuel, Laboune, Farida, Tekman, Mehmet, Diouf, Ababacar, Miura, Kazutoyo, Francica, Joseph R., Ransier, Amy, Long, Carole A., Silk, Sarah E., Payne, Ruth O., Minassian, Angela M., Lauffenburger, Douglas A., Seder, Robert A., Douek, Daniel C., Alter, Galit, Draper, Simon J.
Publicado 2023

In vivo characterization of the physicochemical properties of TLR agonist delivery that enhance vaccine immunogenicity

por Lynn, Geoffrey M., Laga, Richard, Darrah, Patricia A., Ishizuka, Andrew S., Balaci, Alexandra J., Dulcey, Andrés E., Pechar, Michal, Pola, Robert, Gerner, Michael Y., Yamamoto, Ayako, Buechler, Connor R., Quinn, Kylie M., Smelkinson, Margery G., Vanek, Ondrej, Cawood, Ryan, Hills, Thomas, Vasalatiy, Olga, Kastenmuller, Kathrin, Francica, Joseph R., Stutts, Lalisa, Tom, Janine K., Ryu, Keun Ah, Esser-Kahn, Aaron P., Etrych, Tomas, Fisher, Kerry D., Seymour, Leonard W., Seder, Robert A.
Publicado 2015

Highly protective antimalarial antibodies via precision library generation and yeast display screening

por Banach, Bailey B., Tripathi, Prabhanshu, Da Silva Pereira, Lais, Gorman, Jason, Nguyen, Thuy Duong, Dillon, Marlon, Fahad, Ahmed S., Kiyuka, Patience K., Madan, Bharat, Wolfe, Jacy R., Bonilla, Brian, Flynn, Barbara, Francica, Joseph R., Hurlburt, Nicholas K., Kisalu, Neville K., Liu, Tracy, Ou, Li, Rawi, Reda, Schön, Arne, Shen, Chen-Hsiang, Teng, I-Ting, Zhang, Baoshan, Pancera, Marie, Idris, Azza H., Seder, Robert A., Kwong, Peter D., DeKosky, Brandon J.
Publicado 2022

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

por Francica, Joseph R., Sheng, Zizhang, Zhang, Zhenhai, Nishimura, Yoshiaki, Shingai, Masashi, Ramesh, Akshaya, Keele, Brandon F., Schmidt, Stephen D., Flynn, Barbara J., Darko, Sam, Lynch, Rebecca M., Yamamoto, Takuya, Matus-Nicodemos, Rodrigo, Wolinsky, David, Nason, Martha, Valiante, Nicholas M., Malyala, Padma, De Gregorio, Ennio, Barnett, Susan W., Singh, Manmohan, O'Hagan, Derek T., Koup, Richard A., Mascola, John R., Martin, Malcolm A., Kepler, Thomas B., Douek, Daniel C., Shapiro, Lawrence, Seder, Robert A.
Publicado 2015

Functional human IgA targets a conserved site on malaria sporozoites

por Tan, Joshua, Cho, Hyeseon, Pholcharee, Tossapol, Pereira, Lais S., Doumbo, Safiatou, Doumtabe, Didier, Flynn, Barbara J., Schön, Arne, Kanatani, Sachie, Aylor, Samantha O., Oyen, David, Vistein, Rachel, Wang, Lawrence, Dillon, Marlon, Skinner, Jeff, Peterson, Mary, Li, Shanping, Idris, Azza H., Molina-Cruz, Alvaro, Zhao, Ming, Olano, Lisa Renee, Lee, Patricia J., Roth, Alison, Sinnis, Photini, Barillas-Mury, Carolina, Kayentao, Kassoum, Ongoiba, Aissata, Francica, Joseph R., Traore, Boubacar, Wilson, Ian A., Seder, Robert A., Crompton, Peter D.
Publicado 2021

Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T cell immunity to tumor antigens

por Lynn, Geoffrey M., Sedlik, Christine, Baharom, Faezzah, Zhu, Yaling, Ramirez-Valdez, Ramiro A., Coble, Vincent L., Tobin, Kennedy, Nichols, Sarah R., Itzkowitz, Yaakov, Zaidi, Neeha, Gammon, Joshua M., Blobel, Nicolas J., Denizeau, Jordan, de la Rochere, Philippe, Francica, Brian J., Decker, Brennan, Maciejewski, Mateusz, Cheung, Justin, Yamane, Hidehiro, Smelkinson, Margery G., Francica, Joseph R., Laga, Richard, Bernstock, Joshua D., Seymour, Leonard W., Drake, Charles G., Jewell, Christopher M., Lantz, Olivier, Piaggio, Eliane, Ishizuka, Andrew S., Seder, Robert A.
Publicado 2020

DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2

por Parzych, Elizabeth M., Du, Jianqiu, Ali, Ali R., Schultheis, Katherine, Frase, Drew, Smith, Trevor R. F., Cui, Jiayan, Chokkalingam, Neethu, Tursi, Nicholas J., Andrade, Viviane M., Warner, Bryce M., Gary, Ebony N., Li, Yue, Choi, Jihae, Eisenhauer, Jillian, Maricic, Igor, Kulkarni, Abhijeet, Chu, Jacqueline D., Villafana, Gabrielle, Rosenthal, Kim, Ren, Kuishu, Francica, Joseph R., Wootton, Sarah K., Tebas, Pablo, Kobasa, Darwyn, Broderick, Kate E., Boyer, Jean D., Esser, Mark T., Pallesen, Jesper, Kulp, Dan W., Patel, Ami, Weiner, David B.
Publicado 2022

A human monoclonal antibody prevents malaria infection and defines a new site of vulnerability on Plasmodium falciparum circumsporozoite protein

por Kisalu, Neville K., Idris, Azza H., Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J., Sack, Brandon K., Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R., Miller, Alex B., Gregory, Jason, March, Sandra, Liao, Hua-Xin, Haynes, Barton F., Wiehe, Kevin, Trama, Ashley M., Saunders, Kevin O., Gladden, Morgan A., Monroe, Anthony, Bonsignori, Mattia, Kanekiyo, Masaru, Wheatley, Adam K., McDermott, Adrian B., Farney, S. Katie, Chuang, Gwo-Yu, Zhang, Baoshan, Natasha, K C, Chakravarty, Sumana, Kwong, Peter D., Sinnis, Photini, Bhatia, Sangeeta N., Kappe, Stefan H. I., Sim, B. Kim Lee, Hoffman, Stephen L., Zavala, Fidel, Pancera, Marie, Seder, Robert A.
Publicado 2018

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

por Williams, Wilton B., Meyerhoff, R. Ryan, Edwards, R.J., Li, Hui, Manne, Kartik, Nicely, Nathan I., Henderson, Rory, Zhou, Ye, Janowska, Katarzyna, Mansouri, Katayoun, Gobeil, Sophie, Evangelous, Tyler, Hora, Bhavna, Berry, Madison, Abuahmad, A. Yousef, Sprenz, Jordan, Deyton, Margaret, Stalls, Victoria, Kopp, Megan, Hsu, Allen L., Borgnia, Mario J., Stewart-Jones, Guillaume B.E., Lee, Matthew S., Bronkema, Naomi, Moody, M. Anthony, Wiehe, Kevin, Bradley, Todd, Alam, S. Munir, Parks, Robert J., Foulger, Andrew, Oguin, Thomas, Sempowski, Gregory D., Bonsignori, Mattia, LaBranche, Celia C., Montefiori, David C., Seaman, Michael, Santra, Sampa, Perfect, John, Francica, Joseph R., Lynn, Geoffrey M., Aussedat, Baptiste, Walkowicz, William E., Laga, Richard, Kelsoe, Garnett, Saunders, Kevin O., Fera, Daniela, Kwong, Peter D., Seder, Robert A., Bartesaghi, Alberto, Shaw, George M., Acharya, Priyamvada, Haynes, Barton F.
Publicado 2021

Vaccination with SARS-CoV-2 Spike Protein and AS03 Adjuvant Induces Rapid Anamnestic Antibodies in the Lung and Protects Against Virus Challenge in Nonhuman Primates

por Francica, Joseph R., Flynn, Barbara J., Foulds, Kathryn E., Noe, Amy T., Werner, Anne P., Moore, Ian N., Gagne, Matthew, Johnston, Timothy S., Tucker, Courtney, Davis, Rachel L., Flach, Britta, O’Connell, Sarah, Andrew, Shayne F., Lamb, Evan, Flebbe, Dillon R., Nurmukhambetova, Saule T., Donaldson, Mitzi M., Todd, John-Paul M., Zhu, Alex Lee, Atyeo, Caroline, Fischinger, Stephanie, Gorman, Matthew J, Shin, Sally, Edara, Venkata Viswanadh, Floyd, Katharine, Lai, Lilin, Tylor, Alida, McCarthy, Elizabeth, Lecouturier, Valerie, Ruiz, Sophie, Berry, Catherine, Tibbitts, Timothy, Andersen, Hanne, Cook, Anthony, Dodson, Alan, Pessaint, Laurent, Ry, Alex Van, Koutsoukos, Marguerite, Gutzeit, Cindy, Teng, I-Ting, Zhou, Tongqing, Li, Dapeng, Haynes, Barton F., Kwong, Peter D., McDermott, Adrian, Lewis, Mark G., Fu, Tong Ming, Chicz, Roman, van der Most, Robbert, Corbett, Kizzmekia S., Suthar, Mehul S., Alter, Galit, Roederer, Mario, Sullivan, Nancy J., Douek, Daniel C., Graham, Barney S., Casimiro, Danilo, Seder, Robert A.
Publicado 2021