Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors

por Franciosa, Giulia, Olsen, Jesper V.
Publicado 2023

Proteomics to study cancer immunity and improve treatment

por Franciosa, Giulia, Kverneland, Anders H., Jensen, Agnete W. P., Donia, Marco, Olsen, Jesper V.
Publicado 2023

Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures

por Franciosa, Giulia, Smits, Jos G. A., Minuzzo, Sonia, Martinez-Val, Ana, Indraccolo, Stefano, Olsen, Jesper V.
Publicado 2021

ProAlanase is an Effective Alternative to Trypsin for Proteomics Applications and Disulfide Bond Mapping

por Samodova, Diana, Hosfield, Christopher M., Cramer, Christian N., Giuli, Maria V., Cappellini, Enrico, Franciosa, Giulia, Rosenblatt, Michael M., Kelstrup, Christian D., Olsen, Jesper V.
Publicado 2020

Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML

por Pfeiffer, Anamarija, Franciosa, Giulia, Locard-Paulet, Marie, Piga, Ilaria, Reckzeh, Kristian, Vemulapalli, Vidyasiri, Blacklow, Stephen C., Theilgaard-Mönch, Kim, Jensen, Lars J., Olsen, Jesper V.
Publicado 2022

Hybrid-DIA: intelligent data acquisition integrates targeted and discovery proteomics to analyze phospho-signaling in single spheroids

por Martínez-Val, Ana, Fort, Kyle, Koenig, Claire, Van der Hoeven, Leander, Franciosa, Giulia, Moehring, Thomas, Ishihama, Yasushi, Chen, Yu-ju, Makarov, Alexander, Xuan, Yue, Olsen, Jesper V.
Publicado 2023

NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest

por Diluvio, Giulia, Del Gaudio, Francesca, Giuli, Maria Valeria, Franciosa, Giulia, Giuliani, Eugenia, Palermo, Rocco, Besharat, Zein Mersini, Pignataro, Maria Gemma, Vacca, Alessandra, d’Amati, Giulia, Maroder, Marella, Talora, Claudio, Capalbo, Carlo, Bellavia, Diana, Checquolo, Saula
Publicado 2018

Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response

por Giuli, Maria Valeria, Diluvio, Giulia, Giuliani, Eugenia, Franciosa, Giulia, Di Magno, Laura, Pignataro, Maria Gemma, Tottone, Luca, Nicoletti, Carmine, Besharat, Zein Mersini, Peruzzi, Giovanna, Pelullo, Maria, Palermo, Rocco, Canettieri, Gianluca, Talora, Claudio, d’Amati, Giulia, Bellavia, Diana, Screpanti, Isabella, Checquolo, Saula
Publicado 2020

Mapping cardiac remodeling in chronic kidney disease

por Kaesler, Nadine, Cheng, Mingbo, Nagai, James, O’Sullivan, James, Peisker, Fabian, Bindels, Eric M. J., Babler, Anne, Moellmann, Julia, Droste, Patrick, Franciosa, Giulia, Dugourd, Aurelien, Saez-Rodriguez, Julio, Neuss, Sabine, Lehrke, Michael, Boor, Peter, Goettsch, Claudia, Olsen, Jesper V., Speer, Thimoteus, Lu, Tzong-Shi, Lim, Kenneth, Floege, Jürgen, Denby, Laura, Costa, Ivan, Kramann, Rafael
Publicado 2023