Constitutive asymmetric dimerization drives oncogenic activation of epidermal growth factor receptor carboxyl-terminal deletion mutants

por Park, Angela K.J., Francis, Joshua M., Park, Woong-Yang, Park, Joon-Oh, Cho, Jeonghee
Publicado 2015

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

por Zhang, Xiaoyang, Choi, Peter S., Francis, Joshua M., Imielinski, Marcin, Watanabe, Hideo, Cherniack, Andrew D., Meyerson, Matthew
Publicado 2015

Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets

por Lin, Wenchu, Francis, Joshua M., Li, Hong, Gao, Xiaoping, Pedamallu, Chandra Sekhar, Ernst, Patricia, Meyerson, Matthew
Publicado 2016

CHROMOTHRIPSIS FROM DNA DAMAGE IN MICRONUCLEI

por Zhang, Cheng-Zhong, Spektor, Alexander, Cornils, Hauke, Francis, Joshua M., Jackson, Emily K., Liu, Shiwei, Meyerson, Matthew, Pellman, David
Publicado 2015

Utilizing feline oral squamous cell carcinoma patients to develop NQO1-targeted therapy

por Lundberg, Alycen P., Boudreau, Matthew W., Selting, Kim A., Chatkewitz, Lindsay E., Samuelson, Jonathan, Francis, Joshua M., Parkinson, Elizabeth I., Barger, Anne M., Hergenrother, Paul J., Fan, Timothy M.
Publicado 2021

Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5

por Abedalthagafi, Malak S., Merrill, Parker H., Bi, Wenya Linda, Jones, Robert T., Listewnik, Marc L., Ramkissoon, Shakti H., Thorner, Aaron R., Dunn, Ian F., Beroukhim, Rameen, Alexander, Brian M., Brastianos, Priscilla K., Francis, Joshua M., Folkerth, Rebecca D., Ligon, Keith L., Hummelen, Paul Van, Ligon, Azra H., Santagata, Sandro
Publicado 2014

Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation

por Kim, Nayoung, Cho, Ahye, Watanabe, Hideo, Choi, Yoon-La, Aziz, Meraj, Kassner, Michelle, Joung, Je-Gun, Park, Angela KJ, Francis, Joshua M., Bae, Joon Seol, Ahn, Soo-min, Kim, Kyoung-Mee, Park, Joon Oh, Park, Woong-Yang, Ahn, Myung-Ju, Park, Keunchil, Koo, Jaehyung, Yin, Hongwei Holly, Cho, Jeonghee
Publicado 2016

Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia

por Wang, Lili, Fan, Jean, Francis, Joshua M., Georghiou, George, Hergert, Sarah, Li, Shuqiang, Gambe, Rutendo, Zhou, Chensheng W., Yang, Chunxiao, Xiao, Sheng, Cin, Paola Dal, Bowden, Michaela, Kotliar, Dylan, Shukla, Sachet A., Brown, Jennifer R., Neuberg, Donna, Alessi, Dario R., Zhang, Cheng-Zhong, Kharchenko, Peter V., Livak, Kenneth J., Wu, Catherine J.
Publicado 2017

Small-molecule targeting of brachyury transcription factor addiction in chordoma

por Sharifnia, Tanaz, Wawer, Mathias J., Chen, Ting, Huang, Qing-Yuan, Weir, Barbara A., Sizemore, Ann, Lawlor, Matthew A., Goodale, Amy, Cowley, Glenn S., Vazquez, Francisca, Ott, Christopher J., Francis, Joshua M., Sassi, Slim, Cogswell, Patricia, Sheppard, Hadley E., Zhang, Tinghu, Gray, Nathanael S., Clarke, Paul A., Blagg, Julian, Workman, Paul, Sommer, Josh, Hornicek, Francis, Root, David E., Hahn, William C., Bradner, James E., Wong, Kwok K., Clemons, Paul A., Lin, Charles Y., Kotz, Joanne D., Schreiber, Stuart L.
Publicado 2019

Sporadic hemangioblastomas are characterized by cryptic VHL inactivation

por Shankar, Ganesh M, Taylor-Weiner, Amaro, Lelic, Nina, Jones, Robert T, Kim, James C, Francis, Joshua M, Abedalthagafi, Malak, Borges, Lawrence F, Coumans, Jean-Valery, Curry, William T, Nahed, Brian V, Shin, John H, Paek, Sun Ha, Park, Sung-Hye, Stewart, Chip, Lawrence, Michael S, Cibulskis, Kristian, Thorner, Aaron R, Van Hummelen, Paul, Stemmer-Rachamimov, Anat O, Batchelor, Tracy T, Carter, Scott L, Hoang, Mai P, Santagata, Sandro, Louis, David N, Barker, Fred G, Meyerson, Matthew, Getz, Gad, Brastianos, Priscilla K, Cahill, Daniel P
Publicado 2014

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors

por Adalsteinsson, Viktor A., Ha, Gavin, Freeman, Samuel S., Choudhury, Atish D., Stover, Daniel G., Parsons, Heather A., Gydush, Gregory, Reed, Sarah C., Rotem, Denisse, Rhoades, Justin, Loginov, Denis, Livitz, Dimitri, Rosebrock, Daniel, Leshchiner, Ignaty, Kim, Jaegil, Stewart, Chip, Rosenberg, Mara, Francis, Joshua M., Zhang, Cheng-Zhong, Cohen, Ofir, Oh, Coyin, Ding, Huiming, Polak, Paz, Lloyd, Max, Mahmud, Sairah, Helvie, Karla, Merrill, Margaret S., Santiago, Rebecca A., O’Connor, Edward P., Jeong, Seong H., Leeson, Rachel, Barry, Rachel M., Kramkowski, Joseph F., Zhang, Zhenwei, Polacek, Laura, Lohr, Jens G., Schleicher, Molly, Lipscomb, Emily, Saltzman, Andrea, Oliver, Nelly M., Marini, Lori, Waks, Adrienne G., Harshman, Lauren C., Tolaney, Sara M., Van Allen, Eliezer M., Winer, Eric P., Lin, Nancy U., Nakabayashi, Mari, Taplin, Mary-Ellen, Johannessen, Cory M., Garraway, Levi A., Golub, Todd R., Boehm, Jesse S., Wagle, Nikhil, Getz, Gad, Love, J. Christopher, Meyerson, Matthew
Publicado 2017

Allelic variation in class I HLA determines CD8(+) T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2

por Francis, Joshua M., Leistritz-Edwards, Del, Dunn, Augustine, Tarr, Christina, Lehman, Jesse, Dempsey, Conor, Hamel, Andrew, Rayon, Violeta, Liu, Gang, Wang, Yuntong, Wille, Marcos, Durkin, Melissa, Hadley, Kane, Sheena, Aswathy, Roscoe, Benjamin, Ng, Mark, Rockwell, Graham, Manto, Margaret, Gienger, Elizabeth, Nickerson, Joshua, Moarefi, Amir, Noble, Michael, Malia, Thomas, Bardwell, Philip D., Gordon, William, Swain, Joanna, Skoberne, Mojca, Sauer, Karsten, Harris, Tim, Goldrath, Ananda W., Shalek, Alex K., Coyle, Anthony J., Benoist, Christophe, Pregibon, Daniel C., Jilg, Nikolaus, Li, Jonathan, Rosenthal, Alex, Wong, Colline, Daley, George, Golan, David, Heller, Howard, Sharpe, Arlene, Abayneh, Betelihem A., Allen, Patrick, Antille, Diane, Armstrong, Katrina, Boyce, Siobhan, Braley, Joan, Branch, Karen, Broderick, Katherine, Carney, Julia, Chan, Andrew, Davidson, Susan, Dougan, Michael, Drew, David, Elliman, Ashley, Flaherty, Keith, Flannery, Jeanne, Forde, Pamela, Gettings, Elise, Griffin, Amanda, Grimmel, Sheila, Grinke, Kathleen, Hall, Kathryn, Healy, Meg, Henault, Deborah, Holland, Grace, Kayitesi, Chantal, LaValle, Vlasta, Lu, Yuting, Luthern, Sarah, Schneider, Jordan Marchewka, Martino, Brittani, McNamara, Roseann, Nambu, Christian, Nelson, Susan, Noone, Marjorie, Ommerborn, Christine, Pacheco, Lois Chris, Phan, Nicole, Porto, Falisha A, Ryan, Edward, Selleck, Kathleen, Slaughenhaupt, Sue, Sheppard, Kimberly Smith, Suschana, Elizabeth, Wilson, Vivine, Carrington, Mary, Martin, Maureen, Yuki, Yuko, Alter, Galit, Balazs, Alejandro, Bals, Julia, Barbash, Max, Bartsch, Yannic, Boucau, Julie, Carrington, Mary, Chevalier, Josh, Chowdhury, Fatema, DeMers, Edward, Einkauf, Kevin, Fallon, Jon, Fedirko, Liz, Finn, Kelsey, Garcia-Broncano, Pilar, Ghebremichael, Musie S., Hartana, Ciputra, Jiang, Chenyang, Judge, Kelly, Kaplonek, Paulina, Karpell, Marshall, Lai, Peggy, Lam, Evan C., Lefteri, Kristina, Lian, Xiaodong, Lichterfeld, Mathias, Lingwood, Daniel, Liu, Hang, Liu, Jinqing, Ly, Natasha, Hill, Zachary Manickas, Michell, Ashlin, Millstrom, Ilan, Miranda, Noah, O'Callaghan, Claire, Osborn, Matthew, Pillai, Shiv, Rassadkina, Yelizaveta, Reissis, Alexandra, Ruzicka, Francis, Seiger, Kyra, Sessa, Libera, Sharr, Christianne, Shin, Sally, Singh, Nishant, Sun, Weiwei, Sun, Xiaoming, Ticheli, Hannah, Trocha-Piechocka, Alicja, Walker, Bruce, Worrall, Daniel, Yu, Xu G., Zhu, Alex
Publicado 2021