Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease

por Hickey, Miriam A, Zhu, Chunni, Medvedeva, Vera, Lerner, Renata P, Patassini, Stefano, Franich, Nicholas R, Maiti, Panchanan, Frautschy, Sally A, Zeitlin, Scott, Levine, Michael S, Chesselet, Marie-Françoise
Publicado 2012

Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington’s Disease Knock-In Mouse Models

por Franich, Nicholas R., Basso, Manuela, André, Emily A., Ochaba, Joseph, Kumar, Amit, Thein, Soe, Fote, Gianna, Kachemov, Marketta, Lau, Alice L., Yeung, Sylvia Y., Osmand, Alexander, Zeitlin, Scott O., Ratan, Rajiv R., Thompson, Leslie M., Steffan, Joan S.
Publicado 2018

Phenotype onset in Huntington’s disease knock‐in mice is correlated with the incomplete splicing of the mutant huntingtin gene

por Franich, Nicholas R., Hickey, Miriam A., Zhu, Chunni, Osborne, Georgina F., Ali, Nadira, Chu, Tiffany, Bove, Nicholas H., Lemesre, Vincent, Lerner, Renata P., Zeitlin, Scott O., Howland, David, Neueder, Andreas, Landles, Christian, Bates, Gillian P., Chesselet, Marie‐Francoise
Publicado 2019

Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice

por Reidling, Jack C., Relaño-Ginés, Aroa, Holley, Sandra M., Ochaba, Joseph, Moore, Cindy, Fury, Brian, Lau, Alice, Tran, Andrew H., Yeung, Sylvia, Salamati, Delaram, Zhu, Chunni, Hatami, Asa, Cepeda, Carlos, Barry, Joshua A., Kamdjou, Talia, King, Alvin, Coleal-Bergum, Dane, Franich, Nicholas R., LaFerla, Frank M., Steffan, Joan S., Blurton-Jones, Mathew, Meshul, Charles K., Bauer, Gerhard, Levine, Michael S., Chesselet, Marie-Francoise, Thompson, Leslie M.
Publicado 2017