Research Topic on Pseudomonas aeruginosa, Biology, Genetics, and Host–Pathogen Interactions

por Frank, Dara W.
Publicado 2012

Multi-Functional Characteristics of the Pseudomonas aeruginosa Type III Needle-Tip Protein, PcrV; Comparison to Orthologs in other Gram-negative Bacteria

por Sato, Hiromi, Frank, Dara W.
Publicado 2011

Intoxication of Host Cells by the T3SS Phospholipase ExoU: PI(4,5)P(2)-Associated, Cytoskeletal Collapse and Late Phase Membrane Blebbing

por Sato, Hiromi, Frank, Dara W.
Publicado 2014

Five Mechanisms of Manipulation by Bacterial Effectors: A Ubiquitous Theme

por Anderson, David M., Frank, Dara W.
Publicado 2012

Cross Kingdom Activators of Five Classes of Bacterial Effectors

por Anderson, David M., Feix, Jimmy B., Frank, Dara W.
Publicado 2015

Perspectives on the Pseudomonas aeruginosa Type III Secretion System Effector ExoU and Its Subversion of the Host Innate Immune Response to Infection

por Hardy, Kierra S., Tessmer, Maxx H., Frank, Dara W., Audia, Jonathon P.
Publicado 2021

Modified Needle-Tip PcrV Proteins Reveal Distinct Phenotypes Relevant to the Control of Type III Secretion and Intoxication by Pseudomonas aeruginosa

por Sato, Hiromi, Hunt, Meredith L., Weiner, Joshua J., Hansen, Andrew T., Frank, Dara W.
Publicado 2011

The In Vitro Replication Cycle of Achromobacter xylosoxidans and Identification of Virulence Genes Associated with Cytotoxicity in Macrophages

por Pickrum, Adam M., Riegert, Molly O., Wells, Clive, Brockman, Kenneth, Frank, Dara W.
Publicado 2022

Structure and Dynamics of Type III Secretion Effector Protein ExoU As determined by SDSL-EPR Spectroscopy in Conjunction with De Novo Protein Folding

por Fischer, Axel W., Anderson, David M., Tessmer, Maxx H., Frank, Dara W., Feix, Jimmy B., Meiler, Jens
Publicado 2017

Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection

por Wills, Brandon M., Garai, Preeti, Riegert, Molly O., Sanchez, Felix T., Pickrum, Adam M., Frank, Dara W., Brockman, Kenneth L.
Publicado 2023

The effector protein ExoY secreted by Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for GTP

por Voigt, Ulrike, Burhenne, Heike, Sonnow, Lena, Wölfel, Christine, Spangler, Corinna, Ladant, Daniel, Frank, Dara W, Kaever, Volkhard, Seifert, Roland
Publicado 2011

Pseudomonas aeruginosa Exotoxin Y-Mediated Tau Hyperphosphorylation Impairs Microtubule Assembly in Pulmonary Microvascular Endothelial Cells

por Balczon, Ron, Prasain, Nutan, Ochoa, Cristhiaan, Prater, Jason, Zhu, Bing, Alexeyev, Mikhail, Sayner, Sarah, Frank, Dara W., Stevens, Troy
Publicado 2013

Characterization of the ExoU activation mechanism using EPR and integrative modeling

por Tessmer, Maxx H., DeCero, Samuel A., del Alamo, Diego, Riegert, Molly O., Meiler, Jens, Frank, Dara W., Feix, Jimmy B.
Publicado 2020

A Francisella tularensis Schu S4 Purine Auxotroph Is Highly Attenuated in Mice but Offers Limited Protection against Homologous Intranasal Challenge

por Pechous, Roger D., McCarthy, Travis R., Mohapatra, Nrusingh P., Soni, Shilpa, Penoske, Renee M., Salzman, Nita H., Frank, Dara W., Gunn, John S., Zahrt, Thomas C.
Publicado 2008

Pseudomonas aeruginosa ExoY, a cyclic GMP- and cyclic UMP-generating nucleotidyl cyclase

por Seifert, Roland, Hartwig, Christina, Wolter, Sabine, Reinecke, Daniel, Burhenne, Heike, Kaever, Volkhard, Munder, Antje, Tümmler, Burkhard, Schwede, Frank, Grundmann, Manuel, Kostenis, Evi, Frank, Dara W, Beckert, Ulrike
Publicado 2013

In the Absence of Effector Proteins, the Pseudomonas aeruginosa Type Three Secretion System Needle Tip Complex Contributes to Lung Injury and Systemic Inflammatory Responses

por Audia, Jonathon P., Lindsey, Ashley S., Housley, Nicole A., Ochoa, Courtney R., Zhou, Chun, Toba, Michie, Oka, Masahiko, Annamdevula, Naga S., Fitzgerald, Meshann S., Frank, Dara W., Alvarez, Diego F.
Publicado 2013

Virulent Pseudomonas aeruginosa infection converts antimicrobial amyloids into cytotoxic prions

por Voth, Sarah, Gwin, Meredith, Francis, Christopher Michael, Balczon, Ron, Frank, Dara W., Pittet, Jean‐Francois, Wagener, Brant M., Moser, Stephen A., Alexeyev, Mikhail, Housley, Nicole, Audia, Jonathon P., Piechocki, Scott, Madera, Kayla, Simmons, Autumn, Crawford, Michaela, Stevens, Troy
Publicado 2020

Identification, Characterization and Immunogenicity of an O-Antigen Capsular Polysaccharide of Francisella tularensis

por Apicella, Michael A., Post, Deborah M. B., Fowler, Andrew C., Jones, Bradley D., Rasmussen, Jed A., Hunt, Jason R., Imagawa, Sayaka, Choudhury, Biswa, Inzana, Thomas J., Maier, Tamara M., Frank, Dara W., Zahrt, Thomas C., Chaloner, Kathryn, Jennings, Michael P., McLendon, Molly K., Gibson, Bradford W.
Publicado 2010

Gamma secretase activating protein promotes end-organ dysfunction after bacterial pneumonia

por Gwin, Meredith S., Alexeyev, Mikhail F., Geurts, Aron M., Lee, Ji Young, Zhou, Chun, Yang, Xi-Ming, Cohen, Michael V., Downey, James M., Barrington, Robert A., Spadafora, Domenico, Audia, Jonathon P., Frank, Dara W., Voth, Sarah, Pastukh, Viktoriya V., Bell, Jessica, Ayers, Linn, Tambe, Dhananjay T., Nelson, Amy R., Balczon, Ron, Lin, Mike T., Stevens, Troy
Publicado 2023

Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology

por Bagayoko, Salimata, Leon-Icaza, Stephen Adonai, Pinilla, Miriam, Hessel, Audrey, Santoni, Karin, Péricat, David, Bordignon, Pierre-Jean, Moreau, Flavie, Eren, Elif, Boyancé, Aurélien, Naser, Emmanuelle, Lefèvre, Lise, Berrone, Céline, Iakobachvili, Nino, Metais, Arnaud, Rombouts, Yoann, Lugo-Villarino, Geanncarlo, Coste, Agnès, Attrée, Ina, Frank, Dara W., Clevers, Hans, Peters, Peter J., Cougoule, Céline, Planès, Rémi, Meunier, Etienne
Publicado 2021