RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation

por D’Orso, Iván, Frankel, Alan D.
Publicado 2010

HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear

por D’Orso, Iván, Frankel, Alan D.
Publicado 2010

The HIV-1 Rev response element: An RNA scaffold that directs the cooperative assembly of a homo-oligomeric ribonucleoprotein complex

por Fernandes, Jason, Jayaraman, Bhargavi, Frankel, Alan
Publicado 2012

The export receptor Crm1 forms a dimer to promote nuclear export of HIV RNA

por Booth, David S, Cheng, Yifan, Frankel, Alan D
Publicado 2014

Structural basis for cooperative RNA binding and export complex assembly by HIV Rev

por Daugherty, Matthew D., Liu, Bella, Frankel, Alan D.
Publicado 2010

Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability

por Jayaraman, Bhargavi, Fernandes, Jason D., Yang, Shumin, Smith, Cynthia, Frankel, Alan D.
Publicado 2019

RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev–Rev response element complex

por Jayaraman, Bhargavi, Crosby, David C, Homer, Christina, Ribeiro, Isabel, Mavor, David, Frankel, Alan D
Publicado 2014

Functional and structural segregation of overlapping helices in HIV-1

por Safari, Maliheh, Jayaraman, Bhargavi, Yang, Shumin, Smith, Cynthia, Fernandes, Jason D, Frankel, Alan D
Publicado 2022

A Cell-Based Method for Screening RNA-Protein Interactions: Identification of Constitutive Transport Element-Interacting Proteins

por Nakamura, Robert L., Landt, Stephen G., Mai, Emily, Nejim, Jemiel, Chen, Lily, Frankel, Alan D.
Publicado 2012

An SF1 affinity model to identify branch point sequences in human introns

por Pastuszak, Alexander W., Joachimiak, Marcin P., Blanchette, Marco, Rio, Donald C., Brenner, Steven E., Frankel, Alan D.
Publicado 2011

PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription

por Faust, Tyler B., Li, Yang, Jang, Gwendolyn M., Johnson, Jeffrey R., Yang, Shumin, Weiss, Amit, Krogan, Nevan J., Frankel, Alan D.
Publicado 2017

Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions

por Carlson, Christopher R., Asfaha, Jonathan B., Ghent, Chloe M., Howard, Conor J., Hartooni, Nairi, Safari, Maliheh, Frankel, Alan D., Morgan, David O.
Publicado 2020

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

por Faust, Tyler B, Li, Yang, Bacon, Curtis W, Jang, Gwendolyn M, Weiss, Amit, Jayaraman, Bhargavi, Newton, Billy W, Krogan, Nevan J, D'Orso, Iván, Frankel, Alan D
Publicado 2018

Purification and characterization of HIV–human protein complexes

por Jäger, Stefanie, Gulbahce, Natali, Cimermancic, Peter, Kane, Joshua, He, Nanhai, Chou, Seemay, D’Orso, Iván, Fernandes, Jason, Jang, Gwendolyn, Frankel, Alan D., Alber, Tom, Zhou, Qiang, Krogan, Nevan J.
Publicado 2011

GPS-Prot: A web-based visualization platform for integrating host-pathogen interaction data

por Fahey, Marie E, Bennett, Melanie J, Mahon, Cathal, Jäger, Stefanie, Pache, Lars, Kumar, Dhiraj, Shapiro, Alex, Rao, Kanury, Chanda, Sumit K, Craik, Charles S, Frankel, Alan D, Krogan, Nevan J
Publicado 2011

Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies

por Bushman, Frederic D., Malani, Nirav, Fernandes, Jason, D'Orso, Iván, Cagney, Gerard, Diamond, Tracy L., Zhou, Honglin, Hazuda, Daria J., Espeseth, Amy S., König, Renate, Bandyopadhyay, Sourav, Ideker, Trey, Goff, Stephen P., Krogan, Nevan J., Frankel, Alan D., Young, John A. T., Chanda, Sumit K.
Publicado 2009

Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling

por Johnson, Jeffrey R., Crosby, David C., Hultquist, Judd F., Kurland, Andrew P., Adhikary, Prithy, Li, Donna, Marlett, John, Swann, Justine, Hüttenhain, Ruth, Verschueren, Erik, Johnson, Tasha L., Newton, Billy W., Shales, Michael, Simon, Viviana A., Beltrao, Pedro, Frankel, Alan D., Marson, Alexander, Cox, Jeffery S., Fregoso, Oliver I., Young, John A.T., Krogan, Nevan J.
Publicado 2022

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

por Gordon, David E., Jang, Gwendolyn M., Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M., O’Meara, Matthew J., Rezelj, Veronica V., Guo, Jeffrey Z., Swaney, Danielle L., Tummino, Tia A., Huettenhain, Ruth, Kaake, Robyn M., Richards, Alicia L., Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J., Braberg, Hannes, Fabius, Jacqueline M., Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J., Cakir, Merve, McGregor, Michael J., Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Kain, Alice Mac, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T., Melnyk, James E., Chorba, John S., Lou, Kevin, Dai, Shizhong A., Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J.P., Perica, Tina, Pilla, Kala B., Ganesan, Sai J., Saltzberg, Daniel J., Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B., Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A., Bohn, Markus, Safari, Maliheh, Ugur, Fatima S., Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O’Neal, Michael C., Cai, Yiming, C.J.Chang, Jason, Broadhurst, David J., Klippsten, Saker, Sharp, Phillip P., Wenzell, Nicole A., Kuzuoglu, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M., Cavero, Devin A., Hiatt, Joseph, Roth, Theodore L., Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M., Frankel, Alan D., Rosenberg, Oren S., Verba, Kliment A, Agard, David A., Ott, Melanie, Emerman, Michael, Jura, Natalia, von Zastrow, Mark, Verdin, Eric, Ashworth, Alan, Schwartz, Olivier, d’Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S., Fujimori, Danica G., Ideker, Trey, Craik, Charles S., Floor, Stephen N., Fraser, James S., Gross, John D., Sali, Andrej, Roth, Bryan L., Ruggero, Davide, Taunton, Jack, Kortemme, Tanja, Beltrao, Pedro, Vignuzzi, Marco, García-Sastre, Adolfo, Shokat, Kevan M., Shoichet, Brian K., Krogan, Nevan J.
Publicado 2020