The Inflammatory Contribution of B-Lymphocytes and Neutrophils in Progression to Osteoporosis

por Frase, Drew, Lee, Chi, Nachiappan, Chidambaram, Gupta, Richa, Akkouch, Adil
Publicado 2023

Identification of Mubritinib (TAK 165) as an inhibitor of KSHV driven primary effusion lymphoma via disruption of mitochondrial OXPHOS metabolism

por Calderon, Abram, Soldan, Samantha S., De Leo, Alessandra, Deng, Zhong, Frase, Drew M., Anderson, Emma M., Zhang, Yue, Vladimirova, Olga, Lu, Fang, Leung, Jessica C., Murphy, Maureen E., Lieberman, Paul M.
Publicado 2020

Epigenetic Plasticity Enables CNS-Trafficking of EBV-infected B Lymphocytes

por Soldan, Samantha S., Su, Chenhe, Lamontagne, R. Jason, Grams, Nicholas, Lu, Fang, Zhang, Yue, Gesualdi, James D., Frase, Drew M., Tolvinski, Lois E., Martin, Kayla, Messick, Troy E., Fingerut, Jonathan T., Koltsova, Ekaterina, Kossenkov, Andrew, Lieberman, Paul M.
Publicado 2021

Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo

por Gary, Ebony N., Tursi, Nicholas J., Warner, Bryce, Parzych, Elizabeth M., Ali, Ali R., Frase, Drew, Moffat, Estella, Embury-Hyatt, Carissa, Smith, Trevor R.F., Broderick, Kate E., Humeau, Laurent, Kobasa, Darwyn, Patel, Ami, Kulp, Daniel W., Weiner, David B.
Publicado 2022

Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge

por Gary, Ebony N., Tursi, Nicholas J., Warner, Bryce M., Cuismano, Gina, Connors, Jennifer, Parzych, Elizabeth M., Griffin, Bryan D., Bell, Matthew R., Ali, Ali R., Frase, Drew, Hojecki, Casey E., Canziani, Gabriela A., Chaiken, Irwin, Kannan, Toshitha, Moffat, Estella, Embury-Hyatt, Carissa, Wooton, Sarah K., Kossenkov, Andrew, Patel, Ami, Kobasa, Darwyn, Kutzler, Michele A., Haddad, Elias K., Weiner, David B.
Publicado 2023

Prime-boost vaccination regimens with INO-4800 and INO-4802 augment and broaden immune responses against SARS-CoV-2 in nonhuman primates

por Walters, Jewell N., Schouest, Blake, Patel, Ami, Reuschel, Emma L., Schultheis, Katherine, Parzych, Elizabeth, Maricic, Igor, Gary, Ebony N., Purwar, Mansi, Andrade, Viviane M., Doan, Arthur, Elwood, Dustin, Eblimit, Zeena, Nguyen, Brian, Frase, Drew, Zaidi, Faraz I., Kulkarni, Abhijeet, Generotti, Alison, Joseph Kim, J, Humeau, Laurent M., Ramos, Stephanie J., Smith, Trevor R.F., Weiner, David B., Broderick, Kate E.
Publicado 2022

Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection

por Konrath, Kylie M., Liaw, Kevin, Wu, Yuanhan, Zhu, Xizhou, Walker, Susanne N., Xu, Ziyang, Schultheis, Katherine, Chokkalingam, Neethu, Chawla, Himanshi, Du, Jianqiu, Tursi, Nicholas J., Moore, Alan, Adolf-Bryfogle, Jared, Purwar, Mansi, Reuschel, Emma L., Frase, Drew, Sullivan, Matthew, Fry, Benjamin, Maricic, Igor, Andrade, Viviane M., Iffland, Christel, Crispin, Max, Broderick, Kate E., Humeau, Laurent M.P.F., Patel, Ami, Smith, Trevor R.F., Pallesen, Jesper, Weiner, David B., Kulp, Daniel W.
Publicado 2022

DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2

por Parzych, Elizabeth M., Du, Jianqiu, Ali, Ali R., Schultheis, Katherine, Frase, Drew, Smith, Trevor R. F., Cui, Jiayan, Chokkalingam, Neethu, Tursi, Nicholas J., Andrade, Viviane M., Warner, Bryce M., Gary, Ebony N., Li, Yue, Choi, Jihae, Eisenhauer, Jillian, Maricic, Igor, Kulkarni, Abhijeet, Chu, Jacqueline D., Villafana, Gabrielle, Rosenthal, Kim, Ren, Kuishu, Francica, Joseph R., Wootton, Sarah K., Tebas, Pablo, Kobasa, Darwyn, Broderick, Kate E., Boyer, Jean D., Esser, Mark T., Pallesen, Jesper, Kulp, Dan W., Patel, Ami, Weiner, David B.
Publicado 2022

Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial

por Tebas, Pablo, Yang, ShuPing, Boyer, Jean D., Reuschel, Emma L., Patel, Ami, Christensen-Quick, Aaron, Andrade, Viviane M., Morrow, Matthew P., Kraynyak, Kimberly, Agnes, Joseph, Purwar, Mansi, Sylvester, Albert, Pawlicki, Jan, Gillespie, Elisabeth, Maricic, Igor, Zaidi, Faraz I., Kim, Kevin Y., Dia, Yaya, Frase, Drew, Pezzoli, Patrick, Schultheis, Katherine, Smith, Trevor R.F., Ramos, Stephanie J., McMullan, Trevor, Buttigieg, Karen, Carroll, Miles W., Ervin, John, Diehl, Malissa C., Blackwood, Elliott, Mammen, Mammen P., Lee, Jessica, Dallas, Michael J., Brown, Ami Shah, Shea, Jacqueline E., Kim, J.Joseph, Weiner, David B., Broderick, Kate E., Humeau, Laurent M.
Publicado 2020

571. Safety and Immunogenicity of INO-4800, a COVID-19 DNA Vaccine as a Primary Series and Booster

por Tebas, Pablo, Agnes, Joseph, Giffear, Mary, Kraynyak, Kimberly A, Blackwood, Elliott, Amante, Dinah, Reuschel, Emma, Liu, Neiman, Purwar, Mansi, Christensen-Quick, Aaron, Andrade, Viviane M, Carter, Julie, Garufi, Gabriella, Diehl, Malissa, Sylvester, Albert, Morrow, Matthew P, Pezzoli, Patrick P, Kulkarni, Abhijeet J, Zaidi, Faraz I, Frase, Drew, Liaw, Kevin, Patel, Ami, Buttigieg, Karen R, Ervin, John E, Pawlicki, Jan, Gillespie, Elisabeth, Maricic, Igor, Schultheis, Katherine, Badie, Hedieh, Herring, Timothy A, Simon, Keiko O, Smith, Trevor R F, Ramos, Stephanie, Spitz, Robert, Lee, Jessica, Dallas, Michael, Brown, Ami Shah, Shea, Jacqueline E, Kim, J Joseph, Weiner, David, Broderick, Kate, McMullan, Trevor, Boyer, Jean, Humeau, Laurent, Mammen Jr., Mammen P
Publicado 2021