Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics?

por Doliba, Nicolai M., Liu, Qing, Li, Changhong, Chen, Jie, Chen, Pan, Liu, Chengyang, Frederick, David W., Baur, Joseph A., Bennett, Michael J., Naji, Ali, Matschinsky, Franz M.
Publicado 2015

Complementary NAD(+) replacement strategies fail to functionally protect dystrophin-deficient muscle

por Frederick, David W., McDougal, Alan V., Semenas, Melisa, Vappiani, Johanna, Nuzzo, Andrea, Ulrich, John C., Becherer, J. David, Preugschat, Frank, Stewart, Eugene L., Sévin, Daniel C., Kramer, H. Fritz
Publicado 2020

Rapamycin maintains NAD(+)/NADH redox homeostasis in muscle cells

por Zhang, Zhigang, Xu, He N., Li, Siyu, Jr, Antonio Davila, Chellappa, Karthikeyani, Davis, James G., Guan, Yuxia, Frederick, David W., Chu, Weiqing, Zhao, Huaqing, Li, Lin Z., Baur, Joseph A.
Publicado 2020

Deletion of the α-Arrestin Protein Txnip in Mice Promotes Adiposity and Adipogenesis While Preserving Insulin Sensitivity

por Chutkow, William A., Birkenfeld, Andreas L., Brown, Jonathan D., Lee, Hui-Young, Frederick, David W., Yoshioka, Jun, Patwari, Parth, Kursawe, Romy, Cushman, Samuel W., Plutzky, Jorge, Shulman, Gerald I., Samuel, Varman T., Lee, Richard T.
Publicado 2010

SGLT2 Deletion Improves Glucose Homeostasis and Preserves Pancreatic β-Cell Function

por Jurczak, Michael J., Lee, Hui-Young, Birkenfeld, Andreas L., Jornayvaz, Francois R., Frederick, David W., Pongratz, Rebecca L., Zhao, Xiaoxian, Moeckel, Gilbert W., Samuel, Varman T., Whaley, Jean M., Shulman, Gerald I., Kibbey, Richard G.
Publicado 2011

Apolipoprotein CIII Overexpressing Mice Are Predisposed to Diet-Induced Hepatic Steatosis and Hepatic Insulin Resistance

por Lee, Hui-Young, Birkenfeld, Andreas L, Jornayvaz, Francois R, Jurczak, Michael J, Kanda, Shoichi, Popov, Violeta, Frederick, David W, Zhang, Dongyan, Guigni, Blas, Bharadwaj, Kalyani G, Choi, Cheol Soo, Goldberg, Ira J, Park, Jae-Hak, Petersen, Kitt F, Samuel, Varman T, Shulman, Gerald I
Publicado 2011

SirT1 Regulates Adipose Tissue Inflammation

por Gillum, Matthew P., Kotas, Maya E., Erion, Derek M., Kursawe, Romy, Chatterjee, Paula, Nead, Kevin T., Muise, Eric S., Hsiao, Jennifer J., Frederick, David W., Yonemitsu, Shin, Banks, Alexander S., Qiang, Li, Bhanot, Sanjay, Olefsky, Jerrold M., Sears, Dorothy D., Caprio, Sonia, Shulman, Gerald I.
Publicado 2011

Influence of the Hepatic Eukaryotic Initiation Factor 2α (eIF2α) Endoplasmic Reticulum (ER) Stress Response Pathway on Insulin-mediated ER Stress and Hepatic and Peripheral Glucose...

por Birkenfeld, Andreas L., Lee, Hui-Young, Majumdar, Sachin, Jurczak, Michael J., Camporez, Joao Paulo, Jornayvaz, Francois R., Frederick, David W., Guigni, Blas, Kahn, Mario, Zhang, Dongyang, Weismann, Dirk, Arafat, Ayman M., Pfeiffer, Andreas F., Lieske, Stefanie, Oyadomari, Seiichi, Ron, David, Samuel, Varman T., Shulman, Gerald I.
Publicado 2011