Allelic Selection of Amplicons in Glioblastoma Revealed by Combining Somatic and Germline Analysis

por LaFramboise, Thomas, Dewal, Ninad, Wilkins, Katherine, Pe'er, Itsik, Freedman, Matthew L.
Publicado 2010

Prostate cancer disparities in Black men of African descent: a comparative literature review of prostate cancer burden among Black men in the United States, Caribbean, United Kingd...

por Odedina, Folakemi T, Akinremi, Titilola O, Chinegwundoh, Frank, Roberts, Robin, Yu, Daohai, Reams, R Renee, Freedman, Matthew L, Rivers, Brian, Green, B Lee, Kumar, Nagi
Publicado 2009

Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer

por Severson, Tesa, Qiu, Xintao, Alshalalfa, Mohammed, Sjöström, Martin, Quigley, David, Bergman, Andries, Long, Henry, Feng, Felix, Freedman, Matthew L., Zwart, Wilbert, Pomerantz, Mark M.
Publicado 2022

ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer

por Nouruzi, Shaghayegh, Ganguli, Dwaipayan, Tabrizian, Nakisa, Kobelev, Maxim, Sivak, Olena, Namekawa, Takeshi, Thaper, Daksh, Baca, Sylvan C., Freedman, Matthew L., Aguda, Adeleke, Davies, Alastair, Zoubeidi, Amina
Publicado 2022

Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development

por Nameki, Robbin A., Chang, Heidi, Yu, Pak, Abbasi, Forough, Lin, Xianzhi, Reddy, Jessica, Haro, Marcela, Fonseca, Marcos AS, Freedman, Matthew L., Drapkin, Ronny, Corona, Rosario I., Lawrenson, Kate
Publicado 2023

Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study

por Tamimi, Rulla M, Cox, David G, Kraft, Peter, Pollak, Michael N, Haiman, Christopher A, Cheng, Iona, Freedman, Matthew L, Hankinson, Susan E, Hunter, David J, Colditz, Graham A
Publicado 2007

Optimized high-throughput screening of non-coding variants identified from genome-wide association studies

por Morova, Tunc, Ding, Yi, Huang, Chia-Chi F, Sar, Funda, Schwarz, Tommer, Giambartolomei, Claudia, Baca, Sylvan C, Grishin, Dennis, Hach, Faraz, Gusev, Alexander, Freedman, Matthew L, Pasaniuc, Bogdan, Lack, Nathan A
Publicado 2022

Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

por Severson, Tesa M., Zhu, Yanyun, De Marzo, Angelo M., Jones, Tracy, Simons, Jonathan W., Nelson, William G., Yegnasubramanian, Srinivasan, Freedman, Matthew L., Wessels, Lodewyk, Bergman, Andries M., Haffner, Michael C., Zwart, Wilbert
Publicado 2021

A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer

por Walavalkar, Kaivalya, Saravanan, Bharath, Singh, Anurag Kumar, Jayani, Ranveer Singh, Nair, Ashwin, Farooq, Umer, Islam, Zubairul, Soota, Deepanshu, Mann, Rajat, Shivaprasad, Padubidri V., Freedman, Matthew L., Sabarinathan, Radhakrishnan, Haiman, Christopher A., Notani, Dimple
Publicado 2020

Circulating KIM-1 is a minimally invasive biomarker correlated with treatment response to nivolumab in patients with metastatic renal cell carcinoma

por Xu, Wenxin, Vemula, Sai V, Niman, Samuel M, Liu, Xiaowen, Takakura, Ayumi, Huang, Zimo, Choueiri, Toni K, Freedman, Matthew L, Catalano, Paul J, Bonventre, Joseph V, Gupta, Saurabh, McDermott, David F, Bhatt, Rupal S
Publicado 2023

Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer

por Shah, Neel, Wang, Ping, Wongvipat, John, Karthaus, Wouter R, Abida, Wassim, Armenia, Joshua, Rockowitz, Shira, Drier, Yotam, Bernstein, Bradley E, Long, Henry W, Freedman, Matthew L, Arora, Vivek K, Zheng, Deyou, Sawyers, Charles L
Publicado 2017

Androgen receptor and MYC equilibration centralizes on developmental super-enhancer

por Guo, Haiyang, Wu, Yiming, Nouri, Mannan, Spisak, Sandor, Russo, Joshua W., Sowalsky, Adam G., Pomerantz, Mark M., Wei, Zhao, Korthauer, Keegan, Seo, Ji-Heui, Wang, Liyang, Arai, Seiji, Freedman, Matthew L., He, Housheng Hansen, Chen, Shaoyong, Balk, Steven P.
Publicado 2021

CAUSEL: An epigenome and genome editing pipeline for establishing function of non-coding GWAS variants

por Spisak, Sandor, Lawrenson, Kate, Fu, Yanfang, Csabai, Istvan, Cottman, Rebecca T., Haiman, Christopher, Han, Ying, Seo, Ji-Heui, Lenci, Romina, Li, Qiyuan, Tisza, Viktoria, Szallasi, Zoltan, Herbert, Zachery T., Chabot, Matthew, Pomerantz, Mark, Solymosi, Norbert, Gayther, Simon, Joung, J. Keith, Freedman, Matthew L.
Publicado 2015

HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer

por Lu, Xiaodong, Fong, Ka-wing, Gritsina, Galina, Wang, Fang, Baca, Sylvan C., Brea, Lourdes T., Berchuck, Jacob E., Spisak, Sandor, Ross, Jenny, Morrissey, Colm, Corey, Eva, Chandel, Navdeep S., Catalona, William J., Yang, Ximing, Freedman, Matthew L., Zhao, Jonathan C., Yu, Jindan
Publicado 2022

The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis

por Pomerantz, Mark M., Li, Fugen, Takeda, David, Lenci, Romina, Chonkar, Apurva, Chabot, Matthew, Cejas, Paloma, Vazquez, Francisca, Cook, Jennifer, Shivdasani, Ramesh A., Bowden, Michaela, Lis, Rosina, Hahn, William C., Kantoff, Philip W., Brown, Myles, Loda, Massimo, Long, Henry W., Freedman, Matthew L.
Publicado 2015

Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer

por Lin, Xianzhi, Spindler, Tassja J., de Souza Fonseca, Marcos Abraão, Corona, Rosario I., Seo, Ji-Heui, Dezem, Felipe Segato, Li, Lewyn, Lee, Janet M., Long, Henry W., Sellers, Thomas A., Karlan, Beth Y., Noushmehr, Houtan, Freedman, Matthew L., Gayther, Simon A., Lawrenson, Kate
Publicado 2019

A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes

por Mortlock, Sally, Corona, Rosario I., Kho, Pik Fang, Pharoah, Paul, Seo, Ji-Heui, Freedman, Matthew L., Gayther, Simon A., Siedhoff, Matthew T., Rogers, Peter A.W., Leuchter, Ronald, Walsh, Christine S., Cass, Ilana, Karlan, Beth Y., Rimel, B.J., Montgomery, Grant W., Lawrenson, Kate, Kar, Siddhartha P.
Publicado 2022

A transcriptome-wide association study of high grade serous epithelial ovarian cancer identifies novel susceptibility genes and splice variants

por Gusev, Alexander, Lawrenson, Kate, Lin, Xianzhi, Lyra, Paulo C., Kar, Siddhartha, Vavra, Kevin C., Segato, Felipe, Fonseca, Marcos A.S., Lee, Janet M, Pejovic, Tanya, Liu, Gang, Karlan, Beth Y., Freedman, Matthew L., Noushmehr, Houtan, Monteiro, Alvaro N., Pharoah, Paul D.P., Pasaniuc, Bogdan, Gayther, Simon A.
Publicado 2019

Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer

por Corona, Rosario I., Seo, Ji-Heui, Lin, Xianzhi, Hazelett, Dennis J., Reddy, Jessica, Fonseca, Marcos A. S., Abassi, Forough, Lin, Yvonne G., Mhawech-Fauceglia, Paulette Y., Shah, Sohrab P., Huntsman, David G., Gusev, Alexander, Karlan, Beth Y., Berman, Benjamin P., Freedman, Matthew L., Gayther, Simon A., Lawrenson, Kate
Publicado 2020

Patterns of structural variation define prostate cancer across disease states

por Zhou, Meng, Ko, Minjeong, Hoge, Anna C.H., Luu, Kelsey, Liu, Yuzhen, Russell, Magdalena L., Hannon, William W., Zhang, Zhenwei, Carrot-Zhang, Jian, Beroukhim, Rameen, Van Allen, Eliezer M., Choudhury, Atish D., Nelson, Peter S., Freedman, Matthew L., Taplin, Mary-Ellen, Meyerson, Matthew, Viswanathan, Srinivas R., Ha, Gavin
Publicado 2022