Biochemical and mechanistic analysis of the cleavage of branched DNA by human ANKLE1

por Freeman, Alasdair D J, Déclais, Anne-Cécile, Wilson, Timothy J, Lilley, David M J
Publicado 2023

Human ANKLE1 Is a Nuclease Specific for Branched DNA

por Song, Junfang, Freeman, Alasdair D.J., Knebel, Axel, Gartner, Anton, Lilley, David M.J.
Publicado 2020

GEN1 from a Thermophilic Fungus Is Functionally Closely Similar to Non-Eukaryotic Junction-Resolving Enzymes

por Freeman, Alasdair D.J., Liu, Yijin, Déclais, Anne-Cécile, Gartner, Anton, Lilley, David M.J.
Publicado 2014

Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA

por Liu, Yijin, Freeman, Alasdair D.J., Déclais, Anne-Cécile, Wilson, Timothy J., Gartner, Anton, Lilley, David M.J.
Publicado 2015

Analysis of the Intrinsically Disordered N-Terminus of the DNA Junction-Resolving Enzyme T7 Endonuclease I: Identification of Structure Formed upon DNA Binding

por Freeman, Alasdair D. J., Stevens, Michael, Declais, Anne-Cecile, Leahy, Adam, Mackay, Katherine, El Mkami, Hassane, Lilley, David M. J., Norman, David G.
Publicado 2016

Junction resolving enzymes use multivalency to keep the Holliday junction dynamic

por Zhou, Ruobo, Yang, Olivia, Déclais, Anne-Cécile, Jin, Hyeonseok, Gwon, Gwang Hyeon, Freeman, Alasdair D. J., Cho, Yunje, Lilley, David M. J., Ha, Taekjip
Publicado 2019