Generation and Dietary Modulation of Anti-Inflammatory Electrophilic Omega-3 Fatty Acid Derivatives

por Cipollina, Chiara, Salvatore, Sonia R., Muldoon, Matthew F., Freeman, Bruce A., Schopfer, Francisco J.
Publicado 2014

Lipid nitroalkene nanoparticles for the focal treatment of ischemia reperfusion

por Yu, Gary Z, Ramasamy, Thiruganesh, Fazzari, Marco, Chen, Xucai, Freeman, Bruce, Pacella, John J
Publicado 2022

Electrophilic fatty acid nitroalkenes regulate Nrf2 and NF-κB signaling:A medicinal chemistry investigation of structure-function relationships

por Khoo, Nicholas K. H., Li, Lihua, Salvatore, Sonia R., Schopfer, Francisco J., Freeman, Bruce A.
Publicado 2018

Redox properties and human serum albumin binding of nitro-oleic acid

por Zatloukalova, Martina, Mojovic, Milos, Pavicevic, Aleksandra, Kabelac, Martin, Freeman, Bruce A., Pekarova, Michaela, Vacek, Jan
Publicado 2019

Electrophilic characteristics and aqueous behavior of fatty acid nitroalkenes

por Grippo, Valentina, Mojovic, Milos, Pavicevic, Aleksandra, Kabelac, Martin, Hubatka, Frantisek, Turanek, Jaroslav, Zatloukalova, Martina, Freeman, Bruce A., Vacek, Jan
Publicado 2020

Fatty acid nitroalkene reversal of established lung fibrosis

por Koudelka, Adolf, Cechova, Veronika, Rojas, Mauricio, Mitash, Nilay, Bondonese, Anna, St. Croix, Claudette, Ross, Mark A., Freeman, Bruce A.
Publicado 2021

Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling

por Zhou, Chaoming, Ramaswamy, Swarna S., Johnson, Derrick E., Vitturi, Dario A., Schopfer, Franciso J., Freeman, Bruce A., Hudmon, Andy, Levitan, Edwin S.
Publicado 2016

Neuroprotective actions of a fatty acid nitroalkene in Parkinson’s disease

por Di Maio, Roberto, Keeney, Matthew T., Cechova, Veronika, Mortimer, Amanda, Sekandari, Ahssan, Rowart, Pascal, Greenamyre, J. Timothy, Freeman, Bruce A., Fazzari, Marco
Publicado 2023

Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease

por Chowdhury, Fabliha A., Colussi, Nicole, Sharma, Malini, Wood, Katherine C., Xu, Julia Z., Freeman, Bruce A., Schopfer, Francisco J., Straub, Adam C.
Publicado 2023

Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis

por Khoo, Nicholas K.H., Fazzari, Marco, Chartoumpekis, Dionysios V., Li, Lihua, Guimaraes, Danielle Aparecida, Arteel, Gavin E., Shiva, Sruti, Freeman, Bruce A.
Publicado 2019

TRP Channel Agonists Activate Different Afferent Neuromodulatory Mechanisms in Guinea Pig Urinary Bladder

por Daugherty, Stephanie L., Beckel, Jonathan M., Kim, Kyoungeun A., Freeman, Bruce A., Liu, Jiaxin, Wang, Shaoyong, de Groat, William C., Zhang, Xiulin
Publicado 2021

Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO(2)) and nitroalkene (RNO(2)) substituents

por Fazzari, Marco, Woodcock, Steven R., Rowart, Pascal, Ricart, Karina, Lancaster, Jack R., Patel, Rakesh, Vitturi, Dario A., Freeman, Bruce A., Schopfer, Francisco J.
Publicado 2021

Electrophilic nitro-fatty acids suppress psoriasiform dermatitis: STAT3 inhibition as a contributory mechanism

por Wang, Peng, Killeen, Meaghan E., Sumpter, Tina L., Ferris, Laura K., Falo, Louis D., Freeman, Bruce A., Schopfer, Francisco J., Mathers, Alicia R.
Publicado 2021

Convergence of Biological Nitration and Nitrosation via Symmetrical Nitrous Anhydride

por Vitturi, Dario A., Minarrieta, Lucia, Salvatore, Sonia R., Postlethwait, Edward M., Fazzari, Marco, Ferrer-Sueta, Gerardo, Lancaster, Jack R., Freeman, Bruce A., Schopfer, Francisco J.
Publicado 2015

Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages

por Vazquez, Matias M., Gutierrez, Maria V., Salvatore, Sonia R., Puiatti, Marcelo, Dato, Virginia Actis, Chiabrando, Gustavo A., Freeman, Bruce A., Schopfer, Francisco J., Bonacci, Gustavo
Publicado 2020

Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis

por Jobbagy, Soma, Vitturi, Dario A., Salvatore, Sonia R., Turell, Lucía, Pires, Maria F., Kansanen, Emilia, Batthyany, Carlos, Lancaster, Jack R., Freeman, Bruce A., Schopfer, Francisco J.
Publicado 2018

Olives and Olive Oil Are Sources of Electrophilic Fatty Acid Nitroalkenes

por Fazzari, Marco, Trostchansky, Andrés, Schopfer, Francisco J., Salvatore, Sonia R., Sánchez-Calvo, Beatriz, Vitturi, Dario, Valderrama, Raquel, Barroso, Juan B., Radi, Rafael, Freeman, Bruce A., Rubbo, Homero
Publicado 2014

Molecular recognition of nitrated fatty acids by PPARγ

por Li, Yong, Zhang, Jifeng, Schopfer, Francisco J, Martynowski, Dariusz, Garcia-Barrio, Minerva T, Kovach, Amanda, Suino-Powell, Kelly, Baker, Paul R S, Freeman, Bruce A, Chen, Y Eugene, Xu, H Eric
Publicado 2008

Electrophilic nitroalkene-tocopherol derivatives: synthesis, physicochemical characterization and evaluation of anti-inflammatory signaling responses

por Rodriguez-Duarte, Jorge, Dapueto, Rosina, Galliussi, Germán, Turell, Lucía, Kamaid, Andrés, Khoo, Nicholas K. H., Schopfer, Francisco J., Freeman, Bruce A., Escande, Carlos, Batthyány, Carlos, Ferrer-Sueta, Gerardo, López, Gloria V.
Publicado 2018

Meta-omics profiling of the gut-lung axis illuminates metabolic networks and host-microbial interactions associated with elevated lung elastance in a murine model of obese allergic...

por Heinrich, Victoria A., Uvalle, Crystal, Manni, Michelle L., Li, Kelvin, Mullett, Steven J., Donepudi, Sri Ramya, Clader, Jason, Fitch, Adam, Ellgass, Madeline, Cechova, Veronika, Qin, Shulin, Holguin, Fernando, Freeman, Bruce A., Methé, Barbara A., Morris, Alison, Gelhaus, Stacy L.
Publicado 2023