Development of an Oral Form of Azacytidine: 2′3′5′Triacetyl-5-Azacytidine

por Ziemba, Amy, Hayes, Eugene, Freeman, Burgess B., Ye, Tao, Pizzorno, Giuseppe
Publicado 2011

Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice

por Annu, Kavya, Yasuda, Kazuto, Caufield, William V., Freeman, Burgess B., Schuetz, Erin G.
Publicado 2021

Efficacy of oseltamivir treatment in influenza virus-infected obese mice

por Honce, Rebekah, Jones, Jeremy, Meliopoulos, Victoria A., Livingston, Brandi, Sharp, Bridgett, Estrada, Leonardo D., Wang, Lindsey, Caulfield, William, Freeman, Burgess, Govorkova, Elena, Schultz-Cherry, Stacey
Publicado 2023

Pharmacokinetics and Efficacy of the Spleen Tyrosine Kinase Inhibitor R406 after Ocular Delivery for Retinoblastoma

por Pritchard, Eleanor M., Stewart, Elizabeth, Zhu, Fangyi, Bradley, Cori, Griffiths, Lyra, Yang, Lei, Suryadevara, Praveen Kumar, Zhang, Jiakun, Freeman, Burgess B., Guy, R. Kiplin, Dyer, Michael A.
Publicado 2014

Preclinical studies of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in pediatric brain tumors

por Morfouace, Marie, Nimmervoll, Birgit, Boulos, Nidal, Patel, Yogesh T., Shelat, Anang, Freeman, Burgess B., Robinson, Giles W., Wright, Karen, Gajjar, Amar, Stewart, Clinton F., Gilbertson, Richard J., Roussel, Martine F.
Publicado 2015

Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones

por Chen, Yizhe, Zhu, Fangyi, Hammill, Jared, Holbrook, Gloria, Yang, Lei, Freeman, Burgess, White, Karen L., Shackleford, David M., O’Loughlin, Kathleen G., Charman, Susan A., Mirsalis, Jon C., Guy, R. Kiplin
Publicado 2021

Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo

por Jonchere, Barbara, Williams, Justin, Zindy, Frederique, Liu, Jingjing, Robinson, Sarah, Farmer, Dana M., Min, Jaeki, Yang, Lei, Stripay, Jennifer L., Wang, Yingzhe, Freeman, Burgess B., Yu, Jiyang, Shelat, Anang A., Rankovic, Zoran, Roussel, Martine F.
Publicado 2023

CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss

por Teitz, Tal, Fang, Jie, Goktug, Asli N., Bonga, Justine D., Diao, Shiyong, Hazlitt, Robert A., Iconaru, Luigi, Morfouace, Marie, Currier, Duane, Zhou, Yinmei, Umans, Robyn A., Taylor, Michael R., Cheng, Cheng, Min, Jaeki, Freeman, Burgess, Peng, Junmin, Roussel, Martine F., Kriwacki, Richard, Guy, R. Kiplin, Chen, Taosheng, Zuo, Jian
Publicado 2018

Orthotopic Patient-Derived Xenografts of Pediatric Solid Tumors

por Stewart, Elizabeth, Federico, Sara M., Chen, Xiang, Shelat, Anang A., Bradley, Cori, Gordon, Brittney, Karlstrom, Asa, Twarog, Nathaniel R., Clay, Michael R., Bahrami, Armita, Freeman, Burgess B., Xu, Beisi, Zhou, Xin, Wu, Jianrong, Honnell, Victoria, Ocarz, Monica, Blankenship, Kaley, Dapper, Jason, Mardis, Elaine R., Wilson, Richard K., Downing, James, Zhang, Jinghui, Easton, John, Pappo, Alberto, Dyer, Michael A.
Publicado 2017

Combining SJ733, an oral ATP4 inhibitor of Plasmodium falciparum, with the pharmacokinetic enhancer cobicistat: An innovative approach in antimalarial drug development

por Gaur, Aditya H., Panetta, John C., Smith, Amber M., Dallas, Ronald H., Freeman, Burgess B., Stewart, Tracy B., Tang, Li, John, Elizabeth, Branum, Kristen C., Patel, Nehali D., Ost, Shelley, Heine, Ryan N., Richardson, Julie L., Hammill, Jared T., Bebrevska, Lidiya, Gusovsky, Fabian, Maki, Noritsugu, Yanagi, Toshiharu, Flynn, Patricia M., McCarthy, James S., Chalon, Stephan, Guy, R. Kiplin
Publicado 2022

Selective Modulation of the Androgen Receptor Activation Function-2 Domain Rescues Degeneration in Spinal Bulbar Muscular Atrophy

por Badders, Nisha M, Korff, Ane, Miranda, Helen C, Vuppala, Pradeep K, Smith, Rebecca B, Winborn, Brett J, Quemin, Emmanuelle R, Sopher, Bryce L, Dearman, Jennifer, Messing, James, Kim, Nam Chul, Moore, Jennifer, Freibaum, Brian D, Kanagaraj, Anderson P, Fan, Baochang, Tillman, Heather, Chen, Ping-Chung, Wang, Yingzhe, Freeman, Burgess B, Li, Yimei, Kim, Hong Joo, La Spada, Albert R, Taylor, J Paul
Publicado 2018

MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma

por Zuckermann, Marc, He, Chen, Andrews, Jared, Sloan-Henry, Roketa, Bianski, Brandon, Xie, Jia, Wang, Yingzhe, Twarog, Nathaniel, Onar-Thomas, Arzu, Ernst, Kati, Yang, Lei, Li, Yong, Dalton, James, Li, Xiaoyu, Chepyala, Divyabharathi, Zhu, Xiaoyan, Zhang, Junyuan, Xu, Ke, Hover, Laura, McKinnon, Peter J, Pfister, Stefan M, Rankovic, Zoran, Freeman, Burgess B, Shelat, Anang A, Chiang, Jason, Jones, David T W, Tinkle, Christopher L, Baker, Suzanne J
Publicado 2022

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

por Diouf, Barthelemy, Wing, Claudia, Panetta, John C., Eddins, Donnie, Lin, Wenwei, Yang, Wenjian, Fan, Yiping, Pei, Deqing, Cheng, Cheng, Delaney, Shannon M., Zhang, Wei, Bonten, Erik J., Crews, Kristine R., Paugh, Steven W., Li, Lie, Freeman, Burgess B., Autry, Robert J., Beard, Jordan A., Ferguson, Daniel C., Janke, Laura J., Ness, Kirsten K., Chen, Taosheng, Zakharenko, Stanislav S., Jeha, Sima, Pui, Ching‐Hon, Relling, Mary V., Eileen Dolan, M., Evans, William E.
Publicado 2021

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma

por Pan, Min, Wright, William C., Chapple, Richard H., Zubair, Asif, Sandhu, Manbir, Batchelder, Jake E., Huddle, Brandt C., Low, Jonathan, Blankenship, Kaley B., Wang, Yingzhe, Gordon, Brittney, Archer, Payton, Brady, Samuel W., Natarajan, Sivaraman, Posgai, Matthew J., Schuetz, John, Miller, Darcie, Kalathur, Ravi, Chen, Siquan, Connelly, Jon Patrick, Babu, M. Madan, Dyer, Michael A., Pruett-Miller, Shondra M., Freeman, Burgess B., Chen, Taosheng, Godley, Lucy A., Blanchard, Scott C., Stewart, Elizabeth, Easton, John, Geeleher, Paul
Publicado 2021