CD4(+)CD25(+) T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion

por Herman, Ann E., Freeman, Gordon J., Mathis, Diane, Benoist, Christophe
Publicado 2004

VISTA: A Mediator of Quiescence and a Promising Target in Cancer Immunotherapy

por Yuan, Long, Tatineni, Jahnavi, Mahoney, Kathleen M., Freeman, Gordon J.
Publicado 2021

A Comparison of Murine PD-1 and PD-L1 Monoclonal Antibodies

por Bu, Melissa T., Yuan, Long, Klee, Alyssa N., Freeman, Gordon J.
Publicado 2022

Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade

por Freeman, Gordon J., Wherry, E. John, Ahmed, Rafi, Sharpe, Arlene H.
Publicado 2006

Expression of lectin-like transcript-1 in human tissues

por Llibre, Alba, Garner, Lucy, Partridge, Amy, Freeman, Gordon J., Klenerman, Paul, Willberg, Chris B.
Publicado 2016

Interferon-γ-induced activation of JAK1 and JAK2 suppresses tumor cell susceptibility to NK cells through upregulation of PD-L1 expression

por Bellucci, Roberto, Martin, Allison, Bommarito, Davide, Wang, Kathy, Hansen, Steen H, Freeman, Gordon J, Ritz, Jerome
Publicado 2015

PD-1 Blockade in Chronically HIV-1-Infected Humanized Mice Suppresses Viral Loads

por Seung, Edward, Dudek, Timothy E., Allen, Todd M., Freeman, Gordon J., Luster, Andrew D., Tager, Andrew M.
Publicado 2013

PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity

por Liu, Jing, Bu, Xia, Chu, Chen, Dai, Xiaoming, Asara, John M., Sicinski, Piotr, Freeman, Gordon J., Wei, Wenyi
Publicado 2023

BTLA expression declines on B cells of the aged and is associated with low responsiveness to the trivalent influenza vaccine

por Kannan, Senthil, Kurupati, Raj K., Doyle, Susan A., Freeman, Gordon J., Schmader, Kenneth E., Ertl, Hildegund C.J.
Publicado 2015

Correlation of Apobec Mrna Expression with overall Survival and pd-l1 Expression in Urothelial Carcinoma

por Mullane, Stephanie A., Werner, Lillian, Rosenberg, Jonathan, Signoretti, Sabina, Callea, Marcella, Choueiri, Toni K., Freeman, Gordon J., Bellmunt, Joaquim
Publicado 2016

PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques

por Velu, Vijayakumar, Titanji, Kehmia, Ahmed, Hasan, Shetty, Ravi Dyavar, Chennareddi, Lakshmi S., Freeman, Gordon J., Ahmed, Rafi, Amara, Rama Rao
Publicado 2022

Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model

por Suarez, Eloah Rabello, Chang, De-Kuan, Sun, Jiusong, Sui, Jianhua, Freeman, Gordon J., Signoretti, Sabina, Zhu, Quan, Marasco, Wayne A.
Publicado 2016

mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

por Liu, Heng-Jia, Du, Heng, Khabibullin, Damir, Zarei, Mahsa, Wei, Kevin, Freeman, Gordon J., Kwiatkowski, David J., Henske, Elizabeth P.
Publicado 2023

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

por Francisco, Loise M., Salinas, Victor H., Brown, Keturah E., Vanguri, Vijay K., Freeman, Gordon J., Kuchroo, Vijay K., Sharpe, Arlene H.
Publicado 2009

Combinations of BRAF inhibitor and anti-PD-1/PD-L1 antibody improve survival and tumour immunity in an immunocompetent model of orthotopic murine anaplastic thyroid cancer

por Gunda, Viswanath, Gigliotti, Benjamin, Ndishabandi, Dorothy, Ashry, Tameem, McCarthy, Michael, Zhou, Zhiheng, Amin, Salma, Freeman, Gordon J., Alessandrini, Alessandro, Parangi, Sareh
Publicado 2018

Interaction of SHP-2 SH2 domains with PD-1 ITSM induces PD-1 dimerization and SHP-2 activation

por Patsoukis, Nikolaos, Duke-Cohan, Jonathan S., Chaudhri, Apoorvi, Aksoylar, Halil-Ibrahim, Wang, Qi, Council, Asia, Berg, Anders, Freeman, Gordon J., Boussiotis, Vassiliki A.
Publicado 2020

An affinity threshold for maximum efficacy in anti-PD-1 immunotherapy

por Cowles, Sarah C., Sheen, Allison, Santollani, Luciano, Lutz, Emi A., Lax, Brianna M., Palmeri, Joseph R., Freeman, Gordon J., Wittrup, K. Dane
Publicado 2022

Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection

por Ha, Sang-Jun, Mueller, Scott N., Wherry, E. John, Barber, Daniel L., Aubert, Rachael D., Sharpe, Arlene H., Freeman, Gordon J., Ahmed, Rafi
Publicado 2008

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

por Juneja, Vikram R., McGuire, Kathleen A., Manguso, Robert T., LaFleur, Martin W., Collins, Natalie, Haining, W. Nicholas, Freeman, Gordon J., Sharpe, Arlene H.
Publicado 2017

Extracellular Vesicles Transfer the Receptor Programmed Death-1 in Rheumatoid Arthritis

por Greisen, Stinne R., Yan, Yan, Hansen, Aida S., Venø, Morten T., Nyengaard, Jens R., Moestrup, Søren K., Hvid, Malene, Freeman, Gordon J., Kjems, Jørgen, Deleuran, Bent
Publicado 2017