Small-Molecule Host-Defense Peptide Mimetic Antibacterial and Antifungal Agents Activate Human and Mouse Mast Cells via Mas-Related GPCRs

por Alkanfari, Ibrahim, Freeman, Katie B., Roy, Saptarshi, Jahan, Tahsin, Scott, Richard W., Ali, Hydar
Publicado 2019

Antifungal Potential of Host Defense Peptide Mimetics in a Mouse Model of Disseminated Candidiasis

por Chowdhury, Mobaswar Hossain, Ryan, Lisa Kathleen, Cherabuddi, Kartikeya, Freeman, Katie B., Weaver, Damian G., Pelletier, Jeffry C., Scott, Richard W., Diamond, Gill
Publicado 2018

Amide- and bis-amide-linked highly potent and broadly active antifungal agents for the treatment of invasive fungal infections- towards the discovery of pre-clinical development ca...

por Baugh, Simon D. P., Chaly, Anna, Weaver, Damian G., Whitman, David B., Pelletier, Jeffrey C., Bian, Haiyan, Freeman, Katie B., Reitz, Allen B., Scott, Richard W.
Publicado 2023

A Novel Immunocompetent Mouse Model for Testing Antifungal Drugs Against Invasive Candida albicans Infection

por Ryan, Lisa K., Hise, Amy G, Hossain, Chowdhury Mobaswar, Ruddick, William, Parveen, Rezwana, Freeman, Katie B., Weaver, Damian G., Narra, Hema P., Scott, Richard W., Diamond, Gill
Publicado 2020

De Novo Design of Self-Assembling Foldamers That Inhibit Heparin–Protein Interactions

por Montalvo, Geronda L., Zhang, Yao, Young, Trevor M., Costanzo, Michael J., Freeman, Katie B., Wang, Jun, Clements, Dylan J., Magavern, Emma, Kavash, Robert W., Scott, Richard W., Liu, Dahui, DeGrado, William F.
Publicado 2014

1272. Efficacy of a Non-Peptide, Small Molecule Mimic of Host Defense Proteins in Mouse Models of Disseminated Candidiasis and Aspergillosis

por Scott, Richard W, Baugh, Simon D P, Freeman, Katie B, Weaver, Damian G, Chaly, Anna L, Whitman, David B, Thanna, Sandeep, Diamond, Gill, Nguyen, Phung, Deviney, Ashley, Weiss, William J, Pulse, Mark E, Reitz, Allen B
Publicado 2020

Potent in vitro and in vivo antifungal activity of a small molecule host defense peptide mimic through a membrane-active mechanism

por Menzel, Lorenzo P., Chowdhury, Hossain Mobaswar, Masso-Silva, Jorge Adrian, Ruddick, William, Falkovsky, Klaudia, Vorona, Rafael, Malsbary, Andrew, Cherabuddi, Kartikeya, Ryan, Lisa K., DiFranco, Kristina M., Brice, David C., Costanzo, Michael J., Weaver, Damian, Freeman, Katie B., Scott, Richard W., Diamond, Gill
Publicado 2017