RiPPing apart the rules for peptide natural products

por Imani, Aman S., Freeman, Michael F.
Publicado 2018

Exploring the Role of Conformational Heterogeneity in cis-Autoproteolytic Activation of ThnT

por Buller, Andrew R., Freeman, Michael F., Schildbach, Joel F., Townsend, Craig A.
Publicado 2014

Genome mining- and synthetic biology-enabled production of hypermodified peptides

por Bhushan, Agneya, Egli, Peter J., Peters, Eike E., Freeman, Michael F., Piel, Jörn
Publicado 2019

Autoproteolytic Activation of ThnT Results in Structural Reorganization Necessary for Substrate Binding and Catalysis

por Buller, Andrew R., Labonte, Jason W., Freeman, Michael F., Wright, Nathan T., Schildbach, Joel F., Townsend, Craig A.
Publicado 2012

Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis

por Miller, Fredarla S., Crone, Kathryn K., Jensen, Matthew R., Shaw, Sudipta, Harcombe, William R., Elias, Mikael H., Freeman, Michael F.
Publicado 2021

TaxiBGC: a Taxonomy-Guided Approach for Profiling Experimentally Characterized Microbial Biosynthetic Gene Clusters and Secondary Metabolite Production Potential in Metagenomes

por Gupta, Vinod K., Bakshi, Utpal, Chang, Daniel, Lee, Aileen R., Davis, John M., Chandrasekaran, Sriram, Jin, Yong-Su, Freeman, Michael F., Sung, Jaeyun
Publicado 2022

A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli

por Rust, Michael, Helfrich, Eric J. N., Freeman, Michael F., Nanudorn, Pakjira, Field, Christopher M., Rückert, Christian, Kündig, Tomas, Page, Michael J., Webb, Victoria L., Kalinowski, Jörn, Sunagawa, Shinichi, Piel, Jörn
Publicado 2020

A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds

por Song, Haigang, van der Velden, Niels S., Shiran, Sally L., Bleiziffer, Patrick, Zach, Christina, Sieber, Ramon, Imani, Aman S., Krausbeck, Florian, Aebi, Markus, Freeman, Michael F., Riniker, Sereina, Künzler, Markus, Naismith, James H.
Publicado 2018