Mechanisms of cisplatin sensitivity and resistance in testicular germ cell tumors

por Singh, Ratnakar, Fazal, Zeeshan, Freemantle, Sarah J., Spinella, Michael J.
Publicado 2019

Between a Rock and a Hard Place: An Epigenetic-Centric View of Testicular Germ Cell Tumors

por Singh, Ratnakar, Fazal, Zeeshan, Freemantle, Sarah J., Spinella, Michael J.
Publicado 2021

Evidence for tankyrases as antineoplastic targets in lung cancer

por Busch, Alexander M, Johnson, Kevin C, Stan, Radu V, Sanglikar, Aarti, Ahmed, Yashi, Dmitrovsky, Ethan, Freemantle, Sarah J
Publicado 2013

Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells

por Heim, Kelly C, White, Kristina A, Deng, Dexin, Tomlinson, Craig R, Moore, Jason H, Freemantle, Sarah J, Spinella, Michael J
Publicado 2007

Retinoic Acid Mediates Long-Paced Oscillations in Retinoid Receptor Activity: Evidence for a Potential Role for RIP140

por Heim, Kelly C., Gamsby, Joshua J., Hever, Mary P., Freemantle, Sarah J., Loros, Jennifer J., Dunlap, Jay C., Spinella, Michael J.
Publicado 2009

Epigenetic Remodeling through Downregulation of Polycomb Repressive Complex 2 Mediates Chemotherapy Resistance in Testicular Germ Cell Tumors

por Singh, Ratnakar, Fazal, Zeeshan, Corbet, Andrea K., Bikorimana, Emmanuel, Rodriguez, Jennifer C., Khan, Ema M., Shahid, Khadeeja, Freemantle, Sarah J., Spinella, Michael J.
Publicado 2019

Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting

por Snow, Grace E, Kasper, Allison C, Busch, Alexander M, Schwarz, Elisabeth, Ewings, Katherine E, Bee, Thomas, Spinella, Michael J, Dmitrovsky, Ethan, Freemantle, Sarah J
Publicado 2009

Repression of exogenous gene expression by the retinoic acid target gene G0S2

por MA, TIAN, DONG, JESSICA P., SEKULA, DAVID J., FEI, DENNIS LIANG, LAMPH, WILLIAM W., HENDERSON, MICHAEL, LU, YUN, BLUMEN, STEVEN, FREEMANTLE, SARAH J., DMITROVSKY, ETHAN
Publicado 2013

Reciprocal epigenetic remodeling controls testicular cancer hypersensitivity to hypomethylating agents and chemotherapy

por Singh, Ratnakar, Fazal, Zeeshan, Bikorimana, Emmanuel, Boyd, Raya I., Yerby, Cliff, Tomlin, Megan, Baldwin, Hannah, Shokry, Doha, Corbet, Andrea K., Shahid, Khadeeja, Hattab, Aleyah, Freemantle, Sarah J., Spinella, Michael J.
Publicado 2021

G0S2 promotes antiestrogenic and pro-migratory responses in ER+ and ER- breast cancer cells

por Corbet, Andrea K., Bikorimana, Emmanuel, Boyd, Raya I., Shokry, Doha, Kries, Kelly, Gupta, Ayush, Paton, Anneliese, Sun, Zhengyang, Fazal, Zeeshan, Freemantle, Sarah J., Nelson, Erik R., Spinella, Michael J., Singh, Ratnakar
Publicado 2023

The ISG15-specific protease USP18 regulates stability of PTEN

por Mustachio, Lisa Maria, Kawakami, Masanori, Lu, Yun, Rodriguez-Canales, Jaime, Mino, Barbara, Behrens, Carmen, Wistuba, Ignacio, Bota-Rabassedas, Neus, Yu, Jun, Lee, J. Jack, Roszik, Jason, Zheng, Lin, Liu, Xi, Freemantle, Sarah J., Dmitrovsky, Ethan
Publicado 2016

Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations

por GALIMBERTI, FABRIZIO, BUSCH, ALEXANDER M., CHINYENGETERE, FADZAI, MA, TIAN, SEKULA, DAVID, MEMOLI, VINCENT A., DRAGNEV, KONSTANTIN H., LIU, FANG, JOHNSON, KEVIN C., GUO, YONGLI, FREEMANTLE, SARAH J., ANDREW, ANGELINE S., GRENINGER, PATRICIA, ROBBINS, DAVID J., SETTLEMAN, JEFF, BENES, CYRIL, DMITROVSKY, ETHAN
Publicado 2012

Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas

por Chinyengetere, Fadzai, Sekula, David J., Lu, Yun, Giustini, Andrew J., Sanglikar, Aarti, Kawakami, Masanori, Ma, Tian, Burkett, Sandra S., Eisenberg, Burton L., Wells, Wendy A., Hoopes, Paul J., Demicco, Elizabeth G., Lazar, Alexander J, Torres, Keila E., Memoli, Vincent, Freemantle, Sarah J., Dmitrovsky, Ethan
Publicado 2015

Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine

por Albany, Costantine, Hever-Jardine, Mary P., von Herrmann, Katherine M., Yim, Christina Y., Tam, Janice, Warzecha, Joshua M., Shin, Leah, Bock, Sarah E., Curran, Brian S., Chaudhry, Aneeq S., Kim, Fred, Sandusky, George E., Taverna, Pietro, Freemantle, Sarah J., Christensen, Brock C., Einhorn, Lawrence H., Spinella, Michael J.
Publicado 2016