Albumin binding ligands and albumin conjugate uptake by cancer cells

por Frei, Eva
Publicado 2011

Glacial History Affected Phenotypic Differentiation in the Alpine Plant, Campanula thyrsoides

por Scheepens, J. F., Frei, Eva S., Stöcklin, Jürg
Publicado 2013

Contribution of biotransformation enzymes to the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions, difficult answers

por Stiborová, Marie, Hudeček, Jiří, Frei, Eva, Schmeiser, Heinz H.
Publicado 2008

DNA and histone deacetylases as targets for neuroblastoma treatment

por Stiborová, Marie, Poljaková, Jitka, Eckschlager, Tomáš, Kizek, Rene, Frei, Eva
Publicado 2010

Optimalization of preparation of apo-cytochrome b(5) utilizing apo-myoglobin

por Mrázová, Barbora, Martínková, Markéta, Martínek, Václav, Frei, Eva, Stiborová, Marie
Publicado 2008

Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method

por Moserová, Michaela, Kotrbová, Věra, Aimová, Dagmar, Šulc, Miroslav, Frei, Eva, Stiborová, Marie
Publicado 2009

Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches

por Stiborová, Marie, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M., Martínek, Václav
Publicado 2014

Formation of DNA Adducts by Ellipticine and Its Micellar Form in Rats — A Comparative Study

por Stiborova, Marie, Manhartova, Zuzana, Hodek, Petr, Adam, Vojtech, Kizek, Rene, Frei, Eva
Publicado 2014

The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductas...

por Stiborová, Marie, Černá, Věra, Moserová, Michaela, Mrízová, Iveta, Arlt, Volker M., Frei, Eva
Publicado 2014

Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 – similarity between human and rat enzymes

por Svobodová, Martina, Dračínská, Helena, Martínková, Markéta, Hudeček, Jiří, Hodek, Petr, Frei, Eva, Stiborová, Marie
Publicado 2008

Genotoxic mechanisms for the carcinogenicity of the environmental pollutants and carcinogens o-anisidine and 2-nitroanisole follow from adducts generated by their metabolite N-(2-m...

por Stiborová, Marie, Naiman, Karel, Martínková, Markéta, Martínek, Václav, Svobodová, Martina, Schmeiser, Heinz H., Frei, Eva
Publicado 2009

Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2

por Aimová, Dagmar, Poljaková, Jitka, Kotrbová, Věra, Moserová, Michaela, Frei, Eva, Arlt, Volker M., Stiborová, Marie
Publicado 2008

Ellipticine cytotoxicity to cancer cell lines — a comparative study

por Stiborová, Marie, Poljaková, Jitka, Martínková, Eva, Bořek-Dohalská, Lucie, Eckschlager, Tomáš, Kizek, Rene, Frei, Eva
Publicado 2011

Active Site Mutations as a Suitable Tool Contributing to Explain a Mechanism of Aristolochic Acid I Nitroreduction by Cytochromes P450 1A1, 1A2 and 1B1

por Milichovský, Jan, Bárta, František, Schmeiser, Heinz H., Arlt, Volker M., Frei, Eva, Stiborová, Marie, Martínek, Václav
Publicado 2016

Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro: experimental and theoretical approaches

por Martínek, Václav, Bárta, František, Hodek, Petr, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M., Stiborová, Marie
Publicado 2017

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells

por Cerna, Tereza, Hrabeta, Jan, Eckschlager, Tomas, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M., Stiborová, Marie
Publicado 2018

Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study

por Stiborová, Marie, Martínek, Václav, Semanská, Marcela, Hodek, Petr, Dračínský, Martin, Cvačka, Josef, Schmeiser, Heinz H., Frei, Eva
Publicado 2009

Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone

por Mizerovská, Jana, Dračínská, Helena, Arlt, Volker M., Hudeček, Jiří, Hodek, Petr, Schmeiser, Heinz H, Frei, Eva, Stiborová, Marie
Publicado 2008

Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole

por Naiman, Karel, Dračínská, Helena, Dračínský, Martin, Martínková, Markéta, Martínek, Václav, Hodek, Petr, Štícha, Martin, Frei, Eva, Stiborová, Marie
Publicado 2008

NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1

por Stiborová, Marie, Indra, Radek, Moserová, Michaela, Šulc, Miroslav, Hodek, Petr, Frei, Eva, Schmeiser, Heinz H., Arlt, Volker M.
Publicado 2016