Genetic Alterations in Glioma

por Bralten, Linda B. C., French, Pim J.
Publicado 2011

Finding the Right Way to Target EGFR in Glioblastomas; Lessons from Lung Adenocarcinomas

por Gao, Ya, Vallentgoed, Wies R., French, Pim J.
Publicado 2018

A New Landscape for Systemic Pharmacotherapy of Recurrent Glioblastoma?

por Lombardi, Giuseppe, Idbaih, Ahmed, Le Rhun, Emilie, Preusser, Matthias, Zagonel, Vittorina, French, Pim
Publicado 2020

Immunotherapy in Glioblastoma: Current Shortcomings and Future Perspectives

por Weenink, Bas, French, Pim J., Sillevis Smitt, Peter A.E., Debets, Reno, Geurts, Marjolein
Publicado 2020

Recurrent Glioblastoma: From Molecular Landscape to New Treatment Perspectives

por Birzu, Cristina, French, Pim, Caccese, Mario, Cerretti, Giulia, Idbaih, Ahmed, Zagonel, Vittorina, Lombardi, Giuseppe
Publicado 2020

Lack of B and T cell reactivity towards IDH1(R132H) in blood and tumor tissue from LGG patients

por Weenink, Bas, van Brakel, Mandy, Wijers, Rebecca, Sillevis Smitt, Peter A. E., French, Pim J., Debets, Reno
Publicado 2019

The effect of dexamethasone on the microenvironment and efficacy of checkpoint inhibitors in glioblastoma: a systematic review

por Swildens, Kyra X, Sillevis Smitt, Peter A E, van den Bent, Martin J, French, Pim J, Geurts, Marjolein
Publicado 2022

Modeling Prostate Cancer Treatment Responses in the Organoid Era: 3D Environment Impacts Drug Testing

por Van Hemelryk, Annelies, Mout, Lisanne, Erkens-Schulze, Sigrun, French, Pim J., van Weerden, Wytske M., van Royen, Martin E.
Publicado 2021

Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens

por Weenink, Bas, Draaisma, Kaspar, Ooi, Han Z., Kros, Johan M., Sillevis Smitt, Peter A. E., Debets, Reno, French, Pim J.
Publicado 2019

PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients

por Draaisma, Kaspar, Wijnenga, Maarten M. J., Weenink, Bas, Gao, Ya, Smid, Marcel, Robe, P., van den Bent, Martin J., French, Pim J.
Publicado 2015

Alternative normalization and analysis pipeline to address systematic bias in NanoString GeoMx Digital Spatial Profiling data

por van Hijfte, Levi, Geurts, Marjolein, Vallentgoed, Wies R., Eilers, Paul H.C., Sillevis Smitt, Peter A.E., Debets, Reno, French, Pim J.
Publicado 2022

Unique intrahepatic transcriptomics profiles discriminate the clinical phases of a chronic HBV infection

por Hou, Jun, Brouwer, Willem P., Kreefft, Kim, Gama, Lucio, Price, Sarah L., Janssen, Harry L. A., French, Pim J., Vanwolleghem, Thomas, Boonstra, Andre
Publicado 2017

Mutation and drug-specific intracellular accumulation of EGFR predict clinical responses to tyrosine kinase inhibitors

por de Wit, Maurice, Gao, Ya, Mercieca, Darlene, de Heer, Iris, Valkenburg, Bart, van Royen, Martin E., Aerts, Joachim, Sillevis Smitt, Peter, French, Pim
Publicado 2020

Tumor-specific mutations in low-frequency genes affect their functional properties

por Erdem-Eraslan, Lale, Heijsman, Daphne, de Wit, Maurice, Kremer, Andreas, Sacchetti, Andrea, van der Spek, Peter J., Smitt, Peter A. E. Sillevis, French, Pim J.
Publicado 2015

Beyond the Influence of IDH Mutations: Exploring Epigenetic Vulnerabilities in Chondrosarcoma

por Venneker, Sanne, Kruisselbrink, Alwine B., Baranski, Zuzanna, Palubeckaite, Ieva, Briaire-de Bruijn, Inge H., Oosting, Jan, French, Pim J., Danen, Erik H. J., Bovée, Judith V. M. G.
Publicado 2020

IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis

por Gao, Ya, de Wit, Maurice, Struys, Eduard A., van der Linde, Herma C. Z., Salomons, Gajja S., Lamfers, Martine L. M., Willemsen, Rob, Sillevis Smitt, Peter A. E., French, Pim J.
Publicado 2018

Clinical evaluation of a dedicated next generation sequencing panel for routine glioma diagnostics

por Synhaeve, Nathalie E., van den Bent, Martin J., French, Pim J., Dinjens, Winand N. M., Atmodimedjo, Peggy N., Kros, Johan M., Verdijk, R., Dirven, Clemens M. F., Dubbink, Hendrikus J.
Publicado 2018

A bypass mechanism of abiraterone‐resistant prostate cancer: Accumulating CYP17A1 substrates activate androgen receptor signaling

por Moll, Jan M., Kumagai, Jinpei, van Royen, Martin E., Teubel, Wilma J., van Soest, Robert J., French, Pim J., Homma, Yukio, Jenster, Guido, de Wit, Ronald, van Weerden, Wytske M.
Publicado 2019

Deregulated microRNAs in neurofibromatosis type 1 derived malignant peripheral nerve sheath tumors

por Amirnasr, Azadeh, Verdijk, Robert M., van Kuijk, Patricia F., Kartal, Pinar, Vriends, Anne L. M., French, Pim J., van Royen, Martin E., Taal, Walter, Sleijfer, Stefan, Wiemer, Erik A. C.
Publicado 2020

Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas

por van de Geer, Wesley S, Hoogstrate, Youri, Draaisma, Kaspar, Robe, Pierre A, Bins, Sander, Mathijssen, Ron H J, French, Pim, van de Werken, Harmen J G, de Vos, Filip Y F
Publicado 2021