Transcriptional Profiling of Human Brain Endothelial Cells Reveals Key Properties Crucial for Predictive In Vitro Blood-Brain Barrier Models

por Urich, Eduard, Lazic, Stanley E., Molnos, Juliette, Wells, Isabelle, Freskgård, Per-Ola
Publicado 2012

Multicellular Self-Assembled Spheroidal Model of the Blood Brain Barrier

por Urich, Eduard, Patsch, Christoph, Aigner, Stefan, Graf, Martin, Iacone, Roberto, Freskgård, Per-Ola
Publicado 2013

A Human Blood-Brain Barrier Transcytosis Assay Reveals Antibody Transcytosis Influenced by pH-Dependent Receptor Binding

por Sade, Hadassah, Baumgartner, Claudia, Hugenmatter, Adrian, Moessner, Ekkehard, Freskgård, Per-Ola, Niewoehner, Jens
Publicado 2014

Brain Shuttle Neprilysin reduces central Amyloid-β levels

por Campos, Christopher R., Kemble, Alicia M., Niewoehner, Jens, Freskgård, Per-Ola, Urich, Eduard
Publicado 2020

Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier

por Villaseñor, Roberto, Ozmen, Laurence, Messaddeq, Nadia, Grüninger, Fiona, Loetscher, Hansruedi, Keller, Annika, Betsholtz, Christer, Freskgård, Per-Ola, Collin, Ludovic
Publicado 2016

Cargo Delivery into the Brain by in vivo identified Transport Peptides

por Urich, Eduard, Schmucki, Roland, Ruderisch, Nadine, Kitas, Eric, Certa, Ulrich, Jacobsen, Helmut, Schweitzer, Christophe, Bergadano, Alessandra, Ebeling, Martin, Loetscher, Hansruedi, Freskgård, Per-Ola
Publicado 2015

First Infusion Reactions are Mediated by FcγRIIIb and Neutrophils

por Weber, Felix, Breustedt, Daniel, Schlicht, Sonja, Meyer, Claas A., Niewoehner, Jens, Ebeling, Martin, Freskgard, Per-Ola, Bruenker, Peter, Singer, Thomas, Reth, Michael, Iglesias, Antonio
Publicado 2018

Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β

por Henderson, Simon J., Andersson, Christin, Narwal, Rajesh, Janson, Juliette, Goldschmidt, Tom J., Appelkvist, Paulina, Bogstedt, Anna, Steffen, Ann-Charlott, Haupts, Ulrich, Tebbe, Jan, Freskgård, Per Ola, Jermutus, Lutz, Burrell, Matthew, Fowler, Susan B., Webster, Carl I.
Publicado 2014

Delivery of the Brainshuttle™ amyloid-beta antibody fusion trontinemab to non-human primate brain and projected efficacious dose regimens in humans

por Grimm, Hans Peter, Schumacher, Vanessa, Schäfer, Martin, Imhof-Jung, Sabine, Freskgård, Per-Ola, Brady, Kevin, Hofmann, Carsten, Rüger, Petra, Schlothauer, Tilman, Göpfert, Ulrich, Hartl, Maximilian, Rottach, Sylvia, Zwick, Adrian, Seger, Shanon, Neff, Rachel, Niewoehner, Jens, Janssen, Niels
Publicado 2023

Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport

por Ruderisch, Nadine, Schlatter, Daniel, Kuglstatter, Andreas, Guba, Wolfgang, Huber, Sylwia, Cusulin, Carlo, Benz, Jörg, Rufer, Arne Christian, Hoernschemeyer, Joerg, Schweitzer, Christophe, Bülau, Tina, Gärtner, Achim, Hoffmann, Eike, Niewoehner, Jens, Patsch, Christoph, Baumann, Karlheinz, Loetscher, Hansruedi, Kitas, Eric, Freskgård, Per-Ola
Publicado 2017

Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct

por Gehrlein, Alexandra, Udayar, Vinod, Anastasi, Nadia, Morella, Martino L., Ruf, Iris, Brugger, Doris, von der Mark, Sophia, Thoma, Ralf, Rufer, Arne, Heer, Dominik, Pfahler, Nina, Jochner, Anton, Niewoehner, Jens, Wolf, Luise, Fueth, Matthias, Ebeling, Martin, Villaseñor, Roberto, Zhu, Yanping, Deen, Matthew C., Shan, Xiaoyang, Ehsaei, Zahra, Taylor, Verdon, Sidransky, Ellen, Vocadlo, David J., Freskgård, Per-Ola, Jagasia, Ravi
Publicado 2023

Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells

por Patsch, Christoph, Challet-Meylan, Ludivine, Thoma, Eva C., Urich, Eduard, Heckel, Tobias, O’Sullivan, John F, Grainger, Stephanie J, Kapp, Friedrich G., Sun, Lin, Christensen, Klaus, Xia, Yulei, Florido, Mary H. C., He, Wei, Pan, Wei, Prummer, Michael, Warren, Curtis R., Jakob-Roetne, Roland, Certa, Ulrich, Jagasia, Ravi, Freskgård, Per-Ola, Adatto, Isaac, Kling, Dorothee, Huang, Paul, Zon, Leonard I, Chaikof, Elliot L., Gerszten, Robert E., Graf, Martin, Iacone, Roberto, Cowan, Chad A.
Publicado 2015