Immunization with Ty21a live oral typhoid vaccine elicits cross-reactive multifunctional CD8+ T cell responses against Salmonella enterica serovar Typhi, S. Paratyphi A and S. Para...

por Wahid, Rezwanul, Fresnay, Stephanie, Levine, Myron M., Sztein, Marcelo B.
Publicado 2015

A quantitative systems pharmacology approach to support mRNA vaccine development and optimization

por Selvaggio, Gianluca, Leonardelli, Lorena, Lofano, Giuseppe, Fresnay, Stephanie, Parolo, Silivia, Medini, Duccio, Siena, Emilio, Marchetti, Luca
Publicado 2021

Human Salmonella Typhi exposure generates differential multifunctional cross‐reactive T‐cell memory responses against Salmonella Paratyphi and invasive nontyphoidal Salmonella

por Rapaka, Rekha R, Wahid, Rezwanul, Fresnay, Stephanie, Booth, Jayaum S, Darton, Thomas C, Jones, Claire, Waddington, Claire S, Levine, Myron M, Pollard, Andrew J, Sztein, Marcelo B
Publicado 2020

Mucosal-Associated Invariant T cells exhibit distinct functional signatures associated with protection against typhoid fever

por Salerno-Gonçalves, Rosângela, Fresnay, Stephanie, Magder, Laurence, Darton, Thomas C., Waddington, Claire S., Blohmke, Christoph J., Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Publicado 2022

Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans

por Fresnay, Stephanie, McArthur, Monica A., Magder, Laurence, Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Publicado 2016

Importance of Salmonella Typhi-Responsive CD8+ T Cell Immunity in a Human Typhoid Fever Challenge Model

por Fresnay, Stephanie, McArthur, Monica A., Magder, Laurence S., Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Publicado 2017

Challenge of Humans with Wild-type Salmonella enterica Serovar Typhi Elicits Changes in the Activation and Homing Characteristics of Mucosal-Associated Invariant T Cells

por Salerno-Goncalves, Rosângela, Luo, David, Fresnay, Stephanie, Magder, Laurence, Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Publicado 2017

Activation of Salmonella Typhi-Specific Regulatory T Cells in Typhoid Disease in a Wild-Type S. Typhi Challenge Model

por McArthur, Monica A., Fresnay, Stephanie, Magder, Laurence S., Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Dougan, Gordon, Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Publicado 2015

Oral Wild-Type Salmonella Typhi Challenge Induces Activation of Circulating Monocytes and Dendritic Cells in Individuals Who Develop Typhoid Disease

por Toapanta, Franklin R., Bernal, Paula J., Fresnay, Stephanie, Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Dougan, Gordon, Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Publicado 2015

Oral Challenge with Wild-Type Salmonella Typhi Induces Distinct Changes in B Cell Subsets in Individuals Who Develop Typhoid Disease

por Toapanta, Franklin R., Bernal, Paula J., Fresnay, Stephanie, Magder, Laurence S., Darton, Thomas C., Jones, Claire, Waddington, Claire S., Blohmke, Christoph J., Angus, Brian, Levine, Myron M., Pollard, Andrew J., Sztein, Marcelo B.
Publicado 2016