Efficient Access to 2,3-Diarylimidazo[1,2-a]pyridines via a One-Pot, Ligand-Free, Palladium-Catalyzed Three-Component Reaction under Microwave Irradiation

por Wang, Yuanxiang, Frett, Brendan, Li, Hong-yu
Publicado 2014

443 Team Science

por Miah, Sayem, Acharya, Baku, Huda, Md Nazmul, Frett, Brendan
Publicado 2023

(Z)-N-tert-Butyl-2-(4-meth­oxy­anilino)-N′-(4-meth­oxy­phen­yl)-2-phenyl­acetimidamide

por Roberts, Sue A., Saha, Biswajit, Frett, Brendan, Li, Hong-Yu
Publicado 2013

Targeting a Novel G-Quadruplex in the CARD11 Oncogene Promoter with Naptho(2,1-b)furan-1-ethanol,2-nitro- Requires the Nitro Group

por Swafford, Kennith, Acharya, Baku, Xu, Ying-Zhi, Raney, Thomas, McCrury, Mason, Saha, Debasmita, Frett, Brendan, Kendrick, Samantha
Publicado 2022

Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity

por Fang, Yanfen, Kong, Yannan, Xi, Jianbei, Zhu, Mengli, Zhu, Tong, Jiang, Tongtong, Frett, Brendan, Hu, Wenhao, Li, Hong-yu, Ma, Mingliang, Zhang, Xiongwen
Publicado 2016

Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT

por Bharate, Jaideep B., McConnell, Nicholas, Naresh, Gunaganti, Zhang, Lingtian, Lakkaniga, Naga Rajiv, Ding, Lucky, Shah, Neil P., Frett, Brendan, Li, Hong-yu
Publicado 2018

Targeted activity of the small molecule kinase inhibitor Pz-1 towards RET and TRK kinases

por Moccia, Marialuisa, Yang, Donglin, Lakkaniga, Naga Rajiv, Frett, Brendan, McConnell, Nicholas, Zhang, Lingtian, Brescia, Annalisa, Federico, Giorgia, Zhang, Lingzhi, Salerno, Paolo, Santoro, Massimo, Li, Hong-yu, Carlomagno, Francesca
Publicado 2021

Bioisosteric Discovery of NPA101.3, a Second-Generation RET/VEGFR2 Inhibitor Optimized for Single-Agent Polypharmacology

por Moccia, Marialuisa, Frett, Brendan, Zhang, Lingtian, Lakkaniga, Naga Rajiv, Briggs, David C., Chauhan, Rakhee, Brescia, Annalisa, Federico, Giorgia, Yan, Wei, Santoro, Massimo, McDonald, Neil Q., Li, Hong-yu, Carlomagno, Francesca
Publicado 2020