Understanding epithelial homeostasis in the intestine: An old battlefield of ideas, recent breakthroughs and remaining controversies

por De Mey, Jan R., Freund, Jean-Noël
Publicado 2013

A Core Response to the CDX2 Homeoprotein During Development and in Pathologies

por Gourain, Victor, Duluc, Isabelle, Domon-Dell, Claire, Freund, Jean-Noël
Publicado 2021

Key Role of the Cdx2 Homeobox Gene in Extracellular Matrix–mediated Intestinal Cell Differentiation

por Lorentz, Olivier, Duluc, Isabelle, Arcangelis, Adèle De, Simon-Assmann, Patricia, Kedinger, Michèle, Freund, Jean-Noël
Publicado 1997

TAF4 Inactivation Reveals the 3 Dimensional Growth Promoting Activities of Collagen 6A3

por Martianov, Igor, Cler, Emilie, Duluc, Isabelle, Vicaire, Serge, Philipps, Muriel, Freund, Jean-Noel, Davidson, Irwin
Publicado 2014

Functional interaction between the homeoprotein CDX1 and the transcriptional machinery containing the TATA-binding protein

por Calon, Alexandre, Gross, Isabelle, Davidson, Irwin, Kedinger, Michèle, Duluc, Isabelle, Domon-Dell, Claire, Freund, Jean-Noël
Publicado 2007

Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs

por Grall, Emmanuelle, Gourain, Victor, Naïr, Asmaa, Martin, Elisabeth, Birling, Marie-Christine, Freund, Jean-Noël, Duluc, Isabelle
Publicado 2019

SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

por Blache, Philippe, van de Wetering, Marc, Duluc, Isabelle, Domon, Claire, Berta, Philippe, Freund, Jean-Noël, Clevers, Hans, Jay, Philippe
Publicado 2004

CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype

por Barros, Rita, da Costa, Luis Teixeira, Pinto-de-Sousa, João, Duluc, Isabelle, Freund, Jean-Noel, David, Leonor, Almeida, Raquel
Publicado 2010

Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells

por Renouf, Benjamin, Soret, Christine, Saandi, Thoueiba, Delalande, François, Martin, Elisabeth, Vanier, Marie, Duluc, Isabelle, Gross, Isabelle, Freund, Jean-Noël, Domon-Dell, Claire
Publicado 2012

Contribution of Soft Substrates to Malignancy and Tumor Suppression during Colon Cancer Cell Division

por Rabineau, Morgane, Kocgozlu, Leyla, Dujardin, Denis, Senger, Bernard, Haikel, Youssef, Voegel, Jean-Claude, Freund, Jean-Noel, Schaaf, Pierre, Lavalle, Philippe, Vautier, Dominique
Publicado 2013

Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies

por Buchet-Poyau, Karine, Courchet, Julien, Hir, Hervé Le, Séraphin, Bertrand, Scoazec, Jean-Yves, Duret, Laurent, Domon-Dell, Claire, Freund, Jean-Noël, Billaud, Marc
Publicado 2007

The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non–cell-autonomous mechanisms

por Balbinot, Camille, Armant, Olivier, Elarouci, Nabila, Marisa, Laetitia, Martin, Elisabeth, De Clara, Etienne, Onea, Alina, Deschamps, Jacqueline, Beck, Felix, Freund, Jean-Noël, Duluc, Isabelle
Publicado 2018

CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness

por Pereira, Bruno, Sousa, Sofia, Barros, Rita, Carreto, Laura, Oliveira, Patrícia, Oliveira, Carla, Chartier, Nicolas T., Plateroti, Michelina, Rouault, Jean-Pierre, Freund, Jean-Noël, Billaud, Marc, Almeida, Raquel
Publicado 2013

Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration

por Romain, Benoît, Benbrika-Nehmar, Radhia, Marisa, Laetitia, Legrain, Michèle, Lobstein, Viviane, Oravecz, Attila, Poidevin, Laetitia, Bour, Cyril, Freund, Jean-Noël, Duluc, Isabelle, Guenot, Dominique, Pencreach, Erwan
Publicado 2017

Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions

por Giolito, Maria Virginia, La Rosa, Théo, Farhat, Diana, Bodoirat, Serguei, Guardia, Gabriela D. A., Domon‐Dell, Claire, Galante, Pedro A. F., Freund, Jean‐Noel, Plateroti, Michelina
Publicado 2022

The tumor suppressor Apc controls planar cell polarities central to gut homeostasis

por Bellis, Julien, Duluc, Isabelle, Romagnolo, Béatrice, Perret, Christine, Faux, Maree C., Dujardin, Denis, Formstone, Caroline, Lightowler, Sally, Ramsay, Robert G., Freund, Jean-Noël, De Mey, Jan R.
Publicado 2012

Chromatin de-condensation by switching substrate elasticity

por Rabineau, Morgane, Flick, Florence, Ehlinger, Claire, Mathieu, Eric, Duluc, Isabelle, Jung, Matthieu, Senger, Bernard, Kocgozlu, Leyla, Schaaf, Pierre, Lavalle, Philippe, Freund, Jean-Noël, Haikel, Youssef, Vautier, Dominique
Publicado 2018

General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions

por Säisä-Borreill, Susanna, Davidson, Guillaume, Kleiber, Thomas, Thevenot, Andréa, Martin, Elisabeth, Mondot, Stanislas, Blottière, Hervé, Helleux, Alexandra, Mengus, Gabrielle, Plateroti, Michelina, Duluc, Isabelle, Davidson, Irwin, Freund, Jean-Noel
Publicado 2023

CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition

por Galland, Ava, Gourain, Victor, Habbas, Karima, Güler, Yonca, Martin, Elisabeth, Ebel, Claudine, Tavian, Manuela, Vallat, Laurent, Chenard, Marie‐Pierre, Mauvieux, Laurent, Freund, Jean‐Noël, Duluc, Isabelle, Domon‐Dell, Claire
Publicado 2021

The Appendix Orchestrates T-Cell Mediated Immunosurveillance in Colitis-Associated Cancer

por Collard, Maxime K., Tourneur-Marsille, Julien, Uzzan, Mathieu, Albuquerque, Miguel, Roy, Maryline, Dumay, Anne, Freund, Jean-Noël, Hugot, Jean-Pierre, Guedj, Nathalie, Treton, Xavier, Panis, Yves, Ogier-Denis, Eric
Publicado 2022